Articles tagged "Kidney"

2021 American Transplant Congress
Tissue-Specific Features of Immunity Revealed by Single-cell RNA Sequencing of Healthy Human Kidney
S. Q. Crome¹, J. M. Szusz², C. McEvoy¹, J. An¹, S. Clotet-Freixas¹, S. A. MacParland¹, G. D. Bader³, A. Konvalinka¹
¹Toronto General Hospital Research Institute, Ajmera Transplant Centre, University Health Network and the University of Toronto, Toronto, ON, Canada, ²Immunology, University of Toronto, Toronto, ON, Canada, ³Molecular Genetics, University of Toronto, Toronto, ON, Canada
*Purpose: Tissue-resident immune cells reside within distinct niches across organs, where they sustain tissue homeostasis and rapidly respond to perturbations in the local microenvironment. Across…
2021 American Transplant Congress
Outcomes Among CMV Mismatched and Highly Sensitized Kidney Transplant Recipients Who Develop Leukopenia or Neutropenia
S. Brar¹, R. Berry², A. Raval³, Y. Tang³, F. Vincenti², N. Skartsis²
¹University of British Columbia, Vancouver, BC, Canada, ²University of California, San Francisco, San Francisco, CA, ³Merck and Co., Inc., Kenilworth, NJ
*Purpose: Kidney transplant recipients (KTRs) who receive antiproliferative agents for immunosuppression and valganciclovir for CMV prophylaxis are at high risk of developing leukopenia and neutropenia.…
2021 American Transplant Congress
Health-related Quality of Life (HRQoL) in Patients on Dialysis and Kidney Transplant Recipients – Experience with the PROMIS Global-10 Survey
G. Chawla, W. Hajjar, M. Dastgheib, N. Yanga, G. Ahmadzadeh, N. El-Dassouki, A. Shahreza, N. Al Kaabi, N. Edwards, I. Mucsi
University Health Network, Division of Nephrology and Multi-Organ Transplant Program, Toronto, ON, Canada
*Purpose: The PROMIS (Patient-Reported Outcomes Measurement Information System) Global-10 survey has been used to assess HRQoL in population surveys and studies including patients with chronic…
2021 American Transplant Congress
Living Donor Total Robotic Renal Transplantation: Early Single Center Experience
M. E. Tobon Lascano, S. Koganti, M. E. Akoad, M. Anastopoulos, C. J. Simon, B. A. Bouthot, E. D. Walshe, Y. L. Cheah
Transplant, Lahey Clinic, Burlington, MA
*Purpose: To establish the feasibility and evaluate the results and outcomes of a newly established totally robotic kidney transplant program.*Methods: Retrospective review of a single…
2021 American Transplant Congress
Characterization of Chronic Renal Allograft Dysfunction at Single Cell Resolution
C. Kuscu¹, C. Kuscu², A. Shetty³, M. Talwar⁴, J. Eason², D. G. Maluf⁵, V. Mas⁶
¹Surgery, James D Eason Transplant Institute, UTHSC, Memphis, TN, ²Surgery, James D Eason Transplant Institute, Memphis, TN, ³Institute for Genome Sciences, School of Medicine, University of Maryland, Baltimore, MD, ⁴Nephrology, James D Eason Transplant Institute, Memphis, TN, ⁵Surgery, Program in Transplantation - University of Maryland, Baltimore, MD, ⁶Surgery, Division of Surgical Science - University of Maryland, Baltimore, MD
*Purpose: Chronic allograft dysfunction (CAD) is one of the major complications after kidney transplantation. Hereby, we aim to assess the molecular and cellular mechanism of…
2021 American Transplant Congress
One-Year Monitoring of Changes to Kidney-Pancreas Waiting Time Criteria: An OPTN Analysis
R. C. Forbes¹, B. Plucinski², J. White², N. T. Kyaw², R. Kandaswamy³, S. V. Niederhaus⁴
¹Surgery, Vanderbilt University, Nashville, TN, ²UNOS, Richmond, VA, ³Surgery, University of Minnesota, Minneapolis, MN, ⁴Surgery, University of Maryland, Baltimore, MD
*Purpose: In 2018, the OPTN board approved changes to kidney-pancreas (KP) waiting time criteria. KP candidates accrued waiting time if they were (1) on insulin…
2021 American Transplant Congress
Risk Factors Predicting Outcomes in Long-Term Pediatric Kidney Transplant Graft Survival
A. Anand, T. H. Malik, J. Dunson, M. F. McDonald, C. R. Christmann, N. Nguyen Galvan, C. O'Mahony, J. A. Goss, P. R. Srivaths, E. D. Brewer, A. Rana
Baylor College of Medicine, Houston, TX
*Purpose: Pediatric kidney transplant recipients generally have good outcomes post-transplantation; however, the younger age and longer lifespan after transplantation in the pediatric population make understanding…
2021 American Transplant Congress
Centre Variation in Emergency Hospital Readmissions Following Renal Transplantation in England
J. Peracha¹, D. Pitcher¹, R. Steenkamp¹, J. Medcalf², G. Lipkin³, D. Nitsch⁴, W. McKane⁵
¹UK Renal Registry, Bristol, United Kingdom, ²John Walls Renal Unit, Leicester General Hospital, Leicester, United Kingdom, ³University Hospitals Birmingham, Birmingham, United Kingdom, ⁴London School of Hygiene and Trpoical Medicine, London, United Kingdom, ⁵Sheffield Kidney Institute, Northern General Hospital, Sheffield, United Kingdom
*Purpose: Emergency hospital readmissions (EHR) following surgery are associated with significant patient distress, morbidity and costs to healthcare providers. In this study we aim to…
2021 American Transplant Congress
Sigma-1 Receptor Agonists are Renoprotective in Experimental Kidney Transplantation
A. Hosszu¹, T. Lakat¹, A. Toth¹, D. Balogh¹, J. Hodrea¹, L. J. Wagner², A. J. Szabo¹, A. Fekete¹
¹1st Department of Pediatrics, Semmelweis University, Budapest, Hungary, ²Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary
*Purpose: Kidney transplantation (Tx) is associated with better quality of life and reduced costs compared to dialysis, but the shortage in donor organs is a…
2021 American Transplant Congress
Delay in Pediatric Kidney Transplantation Due to Infection: A Single Center Study
T. A. Heald-Sargent¹, S. Manz², P. Verghese³
¹Pediatric Infectious Diseases, Lurie Children's Hospital/Northwestern University, Chicago, IL, ²Central Michigan University, Mt Pleasant, MI, ³Pediatric Kidney Diseases, Lurie Children's Hospital/Northwestern University, Chicago, IL
*Purpose: The infectious risks of immunosuppression following pediatric kidney transplant are well described but little is known about the impact of infections on patients with…