Articles tagged "Kidney"

2021 American Transplant Congress
Renal Transplant Outcomes of Kidney-only vs. Multi-organ Deceased Donors
J. Espinales¹, Z. C. Giffen¹, D. Schneider², R. James³, N. Koizumi³, O. Ekwenna¹, J. Ortiz⁴
¹University of Toledo Medical Center, Toledo, OH, ²UC Irvine School of Medicine, Irvine, CA, ³George Mason University, Arlington, VA, ⁴Albany Medical Center, Albany, NY
*Purpose: We sought to determine the relative outcomes of kidneys from kidney-only or multi-organ deceased donors.*Methods: Scientific Registry of Transplant Recipients data from 2010-2019 were…
2021 American Transplant Congress
Late Subclinical Rejection and Borderline Rejection in Kidney Transplant Patients is Associated with Increased Incidence of Subsequent Clinical Rejections
V. Viswanathan¹, I. Melgarejo², C. Puttarajappa², P. Sood², M. Molinari², S. Hariharan², C. Wu², A. Sharma², N. Shah², R. Mehta²
¹Department of Medicine, Renal-Electrolyte Division, University of Pittsburgh Medical Center, Pittsburgh, PA, ²Department of Surgery, Thomas E. Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: The outcomes of inflammatory changes noted in late surveillance biopsies (1 year) is unclear.*Methods: Patients transplanted (live donor and deceased donor) at our center…
2021 American Transplant Congress
Frequency and Types of Pharmacist Interventions and Risk Assessments Occurring During the 12-Month Transafe Rx Randomized Controlled Trial
H. M. Gonzales, J. N. Fleming, D. J. Taber
MUSC, Charleston, SC
*Purpose: Clinical pharmacists have unique education and training to identify and mitigate medication (med) safety issues in high-risk populations, such as kidney transplant (KTX). The…
2021 American Transplant Congress
Long-term Outcomes of Early Steroid Withdrawal (SW) After Kidney Transplant
D. Vock¹, A. Matas²
¹University of Minnesota School of Public Health, Minneapolis, MN, ²University of Minnesota Medical School, Minneapolis, MN
*Purpose: Early SW (10 years) graft failure associated with early SW.*Conclusions: We conclude that early SW has similar or better long-term outcomes than maintenance prednisone.
2021 American Transplant Congress
Long-Term Outcomes in Older Kidney Transplant Recipients from Older Donors
E. Cuadrado-Payán, E. Montagud-Marrahi, J. Casals-Urquiza, J. del Risco-Zevallos, D. Cucchiari, P. Ventura-Aguiar, I. Revuelta, G. Piñeiro, N. Esforzado, F. Cofan, J. Ugalde, J. Campistol, F. Oppenheimer, J. Torregrosa, F. Diekmann
Nephrology and Kidney Transplantation, Hospital Clínic de Barcelona, Barcelona, Spain
*Purpose: The age of patients referred for kidney transplantation has increased progressively. However, the precise influence of age on hard outcomes after transplantation is controversial*Methods:…
2021 American Transplant Congress
Pill Burden in Belatacept versus Tacrolimus-Based Immunosuppression
S. Gattis, L. Lakhani, A. Basu
Emory Healthcare, Atlanta, GA
*Purpose: Medication non-adherence is a major barrier amongst renal transplant recipients, and improvement can be seen after reduction in pill burden. Belatacept versus tacrolimus-based immunosuppression…
2021 American Transplant Congress
Bortezomib for Antibody-Mediated Rejection of Renal Transplant in Youth
L. Galea, J. Hewlett, J. Savant, S. Lopez, S. Amaral, B. Viteri
The Children’s Hospital of Philadelphia, Philadelphia, PA
*Purpose: The purpose of the study was to examine preliminary efficacy and tolerability of bortezomib, a protease inhibitor, in treatment-refractory antibody mediated rejection (AMR) in…
2021 American Transplant Congress
Prostate Cancer Mortality is Not Worse Among Kidney Transplant Recipients Compared to Dialysis Patients
N. Sarabu¹, W. Dong², S. M. Koroukian²
¹University Hospital Cleveland Medical Center, Cleveland, OH, ²Case Western Reserve University, Cleveland, OH
*Purpose: Recent recommendations from expert panel of American Society of Transplantation (AST) state that most patients with prostate cancer (PCa) do not need to wait…
2021 American Transplant Congress
COVID-19 in the Kidney Transplant Waitlist Population
A. C. Johnson¹, C. P. Larsen¹, H. Gebel², R. Bray²
¹Surgery, Emory University, Atlanta, GA, ²Pathology, Emory University, Atlanta, GA
*Purpose: Through banked serum samples from transplant candidates across Georgia, we characterize the prevalence, timing, and duration of SARS-CoV-2 seropositivity and investigate the impact on…
2021 American Transplant Congress
Contribution of T-bet Expressing CD27+ CD21- Activated Memory B Cells Poised for Plasma Cell Differentiation to Antibody-mediated Rejection of Kidney Transplants
K. Louis¹, E. Bailly¹, C. Macedo¹, B. Ramaswami¹, X. Gu¹, G. Chalasani¹, A. Zeevi¹, P. Randhawa¹, H. Singh², C. Lefaucheur³, D. Metes¹
¹Surgery, University of Pittsburgh, Pittsburgh, PA, ²Center for Systems immunology, Department of Immunology, University of Pittsburgh, Pittsburgh, PA, ³Human Immunology and Immunopathology, INSERM U976, Paris, France
*Purpose: Alloimmunity triggered by donor-specific antibodies (DSAs) and ensuing development of antibody-mediated rejection (ABMR) are detrimental to organ transplants. Yet, the cellular states underlying B…