Articles tagged "Kidney"

2021 American Transplant Congress
Kidney Transplant Recipients Who Had Covid-19 Prior to Transplant: A Single-center Experience
S. Sultan, M. Aull, R. Craig-Schapiro, E. C. Liu, J. H. Lee, S. Kapur
New York Presbyterian / Weill Cornell, New York, NY
*Purpose: In the early recovery phase after the initial surge of the COVID-19 pandemic, a question emerged in the context of resuming transplant activity: should…
2021 American Transplant Congress
One-year Outcomes of a Multicenter Trial of Transplantation of Hcv Viremic Kidney Donors into Hcv Uninfected Recipients
M. Sise¹, D. Goldberg², D. Schaubel³, J. Kort⁴, R. Alloway⁵, J. Friedewald⁶, R. Fontana⁷, S. Sultan⁸, N. Desai⁹, R. Chung¹, P. Reese¹⁰
¹Mass General Hospital, Boston, MA, ²U-Miami, Miami, FL, ³U. Pennsylvania, Philadelphia, PA, ⁴Abbvie, Chicago, IL, ⁵U Cincinnati, Cincinnati, OH, ⁶Northwestern U., Evanston, IL, ⁷U. Michigan, Ann Arbor, MI, ⁸Cornell, New York City, NY, ⁹Johns Hopkins, Baltimore, MD, ¹⁰U. Pennslyvania, Philadelpha, PA
*Purpose: As interest in transplantation of Hepatitis C virus (HCV)-viremic kidneys into HCV-uninfected (HCV+ to HCV- KT) recipients increases, understanding clinical outcomes beyond HCV clearance…
2021 American Transplant Congress
Patterns and Inhibition of Cell Death During Static Cold Storage of Human Kidneys
J. R. DiRito¹, G. Chickering², J. T. Langford¹, D. Stern¹, S. Hosgood³, M. L. Nicholson³, E. Gavathiotis⁴, R. N. Kitsis⁵, M. Saltzman², J. S. Pober⁶, G. T. Tietjen⁷
¹Surgery, Yale School of Medicine, New Haven, CT, ²Biomedical Engineering, Yale University, New Haven, CT, ³Surgery, University of Cambridge, Cambridge, United Kingdom, ⁴Biochemistry and Medicine, Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, Bronx, NY, ⁵Surgery, Albert Einstein College of Medicine, Bronx, NY, ⁶Immunobiology, Yale University, New Haven, CT, ⁷Surgery and Biomedical Engineering, Yale School of Medicine, New Haven, CT
*Purpose: As the donor population continues to age and accumulate co-morbidities, more marginal kidneys are being retrieved for transplantation. However, estimates suggest that more than…
2021 American Transplant Congress
Covid-19 Reinfection in a Kidney Transplant Patient
Z. Saeed Zafar, D. Malhotra
Nephrology, Yale School of Medicine, New Haven, CT
*Purpose: Several cases have demonstrated positive SARS-CoV-2 PCR testing in patients who were initially shown to have cleared the infection. These reinfections may represent new…
2021 American Transplant Congress
Long Term Outcomes of Kidney Transplantation from Deceased Donors with Terminal Acute Kidney Injury
J. Rogers¹, R. Stratta², A. Farney², G. Orlando², C. Jay², A. Reeves-Daniel³, A. Mena-Gutierrez³, N. Sakhovskaya³, K. Gurung², B. Sharda², J. Rogers²
¹Surgery, Wake Forest School of Medicine, Winston Salem, NC, ²Surgery, Wake Forest Baptist Medical Center, Winston Salem, NC, ³Internal Medicine, Wake Forest Baptist Medical Center, Winston Salem, NC
*Purpose: Long term outcomes of kidney transplantation from deceased donors with terminal acute kidney injury (AKI) are not well defined.*Methods: Single center retrospective review of…
2021 American Transplant Congress
Preempting Misconceptions: An Educational Initiative for Preemptive Kidney Transplant Candidates
T. Menser¹, M. Hobeika², H. Ibrahim², A. Khan¹, B. Cruz², J. Sharp², A. Gaber²
¹Houston Methodist Research Institute, Houston, TX, ²Houston Methodist Hospital, Houston, TX
*Purpose: reemptive living donor kidney transplantation (pLDKT) offers many advantages for patients with advanced chronic kidney disease. However, pLDKT represents less than 1 out of…
2021 American Transplant Congress
De Novo Atypical Hemolytic Uremic Syndrome (aHUS) in Kidney Transplant Recipients from the Same Donor: Possible Role of Two Genetic Hits
C. Crane¹, J. Sherbotie², S. Anand³
¹University of California at San Diego, San Diego, CA, ²University of Utah School of Medicine, Salt Lake City, UT, ³Nephrology Associates of Utah, Salt Lake City, UT
*Purpose: Thrombotic microangiopathy (TMA) is an uncommon and potentially serious complication of kidney transplantation. Atypical hemolytic uremic syndrome (aHUS) is a type of TMA most…
2021 American Transplant Congress
Dynamic Forecasting of Patient-Specific Kidney Transplant Function with a Sequence-to-Sequence Deep-Learning Model
E. Van Loon¹, W. Zhang², A. Van Craenenbroeck¹, B. De Moor², M. Naesens¹
¹Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium, ²ESAT Stadius Center for Dynamical Systems, Signal Processing and Data Analytics, KU Leuven, Leuven, Belgium
*Purpose: Alike other clinical biomarkers, eGFR trajectories are characterized by intra-individual variability, related to biological fluctuations and analytical error. These fluctuations hamper the distinction between…
2021 American Transplant Congress
Racial and Ethnic Disparities in Pediatric Kidney Transplantation – Has KAS Made a Difference?
O. Charnaya¹, S. Yu², A. Goldberg³, J. Garonzik-Wang², D. Segev², P. Verghese⁴
¹Pediatrics, Johns Hopkins University, Baltimore, MD, ²Transplant Surgery, Johns Hopkins University, Baltimore, MD, ³University of Manitoba, Winninpeg, MB, Canada, ⁴Northwestern University Feinberg School of Medicine, Chicago, IL
*Purpose: Racial and ethnic minority pediatric transplant candidates have known disparities in access to kidney transplantation. The Kidney Allocation System (KAS), implemented in 2014, was…
2021 American Transplant Congress
Covid-19 Incidence Was Initially Associated with Posttransplant Kidney Graft Failure
A. Wey¹, J. Miller¹, D. Musgrove¹, N. Salkowski¹, M. Tabaka¹, R. Hirose², A. Massie³, D. Segev³, A. Israni¹, J. Snyder¹, B. Kasiske¹
¹SRTR, Minneapolis, MN, ²Univ of San Francisco, San Francisco, CA, ³Johns Hopkins, Baltimore, MD
*Purpose: To better understand the effect of COVID-19 on kidney posttransplant outcomes, we estimated the association of county-level COVID-19 incidence with kidney posttransplant graft failure.*Methods:…