Articles tagged "Kidney"

2021 American Transplant Congress
De Novo Atypical Hemolytic Uremic Syndrome (aHUS) in Kidney Transplant Recipients from the Same Donor: Possible Role of Two Genetic Hits
C. Crane¹, J. Sherbotie², S. Anand³
¹University of California at San Diego, San Diego, CA, ²University of Utah School of Medicine, Salt Lake City, UT, ³Nephrology Associates of Utah, Salt Lake City, UT
*Purpose: Thrombotic microangiopathy (TMA) is an uncommon and potentially serious complication of kidney transplantation. Atypical hemolytic uremic syndrome (aHUS) is a type of TMA most…
2021 American Transplant Congress
Dynamic Forecasting of Patient-Specific Kidney Transplant Function with a Sequence-to-Sequence Deep-Learning Model
E. Van Loon¹, W. Zhang², A. Van Craenenbroeck¹, B. De Moor², M. Naesens¹
¹Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium, ²ESAT Stadius Center for Dynamical Systems, Signal Processing and Data Analytics, KU Leuven, Leuven, Belgium
*Purpose: Alike other clinical biomarkers, eGFR trajectories are characterized by intra-individual variability, related to biological fluctuations and analytical error. These fluctuations hamper the distinction between…
2021 American Transplant Congress
Kidney Transplant Recipients Who Had Covid-19 Prior to Transplant: A Single-center Experience
S. Sultan, M. Aull, R. Craig-Schapiro, E. C. Liu, J. H. Lee, S. Kapur
New York Presbyterian / Weill Cornell, New York, NY
*Purpose: In the early recovery phase after the initial surge of the COVID-19 pandemic, a question emerged in the context of resuming transplant activity: should…
2021 American Transplant Congress
One-year Outcomes of a Multicenter Trial of Transplantation of Hcv Viremic Kidney Donors into Hcv Uninfected Recipients
M. Sise¹, D. Goldberg², D. Schaubel³, J. Kort⁴, R. Alloway⁵, J. Friedewald⁶, R. Fontana⁷, S. Sultan⁸, N. Desai⁹, R. Chung¹, P. Reese¹⁰
¹Mass General Hospital, Boston, MA, ²U-Miami, Miami, FL, ³U. Pennsylvania, Philadelphia, PA, ⁴Abbvie, Chicago, IL, ⁵U Cincinnati, Cincinnati, OH, ⁶Northwestern U., Evanston, IL, ⁷U. Michigan, Ann Arbor, MI, ⁸Cornell, New York City, NY, ⁹Johns Hopkins, Baltimore, MD, ¹⁰U. Pennslyvania, Philadelpha, PA
*Purpose: As interest in transplantation of Hepatitis C virus (HCV)-viremic kidneys into HCV-uninfected (HCV+ to HCV- KT) recipients increases, understanding clinical outcomes beyond HCV clearance…
2021 American Transplant Congress
Patterns and Inhibition of Cell Death During Static Cold Storage of Human Kidneys
J. R. DiRito¹, G. Chickering², J. T. Langford¹, D. Stern¹, S. Hosgood³, M. L. Nicholson³, E. Gavathiotis⁴, R. N. Kitsis⁵, M. Saltzman², J. S. Pober⁶, G. T. Tietjen⁷
¹Surgery, Yale School of Medicine, New Haven, CT, ²Biomedical Engineering, Yale University, New Haven, CT, ³Surgery, University of Cambridge, Cambridge, United Kingdom, ⁴Biochemistry and Medicine, Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, Bronx, NY, ⁵Surgery, Albert Einstein College of Medicine, Bronx, NY, ⁶Immunobiology, Yale University, New Haven, CT, ⁷Surgery and Biomedical Engineering, Yale School of Medicine, New Haven, CT
*Purpose: As the donor population continues to age and accumulate co-morbidities, more marginal kidneys are being retrieved for transplantation. However, estimates suggest that more than…
2021 American Transplant Congress
Covid-19 Reinfection in a Kidney Transplant Patient
Z. Saeed Zafar, D. Malhotra
Nephrology, Yale School of Medicine, New Haven, CT
*Purpose: Several cases have demonstrated positive SARS-CoV-2 PCR testing in patients who were initially shown to have cleared the infection. These reinfections may represent new…
2021 American Transplant Congress
Health-related Quality of Life (HRQoL) in Patients on Dialysis and Kidney Transplant Recipients – Experience with the PROMIS Global-10 Survey
G. Chawla, W. Hajjar, M. Dastgheib, N. Yanga, G. Ahmadzadeh, N. El-Dassouki, A. Shahreza, N. Al Kaabi, N. Edwards, I. Mucsi
University Health Network, Division of Nephrology and Multi-Organ Transplant Program, Toronto, ON, Canada
*Purpose: The PROMIS (Patient-Reported Outcomes Measurement Information System) Global-10 survey has been used to assess HRQoL in population surveys and studies including patients with chronic…
2021 American Transplant Congress
Living Donor Total Robotic Renal Transplantation: Early Single Center Experience
M. E. Tobon Lascano, S. Koganti, M. E. Akoad, M. Anastopoulos, C. J. Simon, B. A. Bouthot, E. D. Walshe, Y. L. Cheah
Transplant, Lahey Clinic, Burlington, MA
*Purpose: To establish the feasibility and evaluate the results and outcomes of a newly established totally robotic kidney transplant program.*Methods: Retrospective review of a single…
2021 American Transplant Congress
Characterization of Chronic Renal Allograft Dysfunction at Single Cell Resolution
C. Kuscu¹, C. Kuscu², A. Shetty³, M. Talwar⁴, J. Eason², D. G. Maluf⁵, V. Mas⁶
¹Surgery, James D Eason Transplant Institute, UTHSC, Memphis, TN, ²Surgery, James D Eason Transplant Institute, Memphis, TN, ³Institute for Genome Sciences, School of Medicine, University of Maryland, Baltimore, MD, ⁴Nephrology, James D Eason Transplant Institute, Memphis, TN, ⁵Surgery, Program in Transplantation - University of Maryland, Baltimore, MD, ⁶Surgery, Division of Surgical Science - University of Maryland, Baltimore, MD
*Purpose: Chronic allograft dysfunction (CAD) is one of the major complications after kidney transplantation. Hereby, we aim to assess the molecular and cellular mechanism of…
2021 American Transplant Congress
One-Year Monitoring of Changes to Kidney-Pancreas Waiting Time Criteria: An OPTN Analysis
R. C. Forbes¹, B. Plucinski², J. White², N. T. Kyaw², R. Kandaswamy³, S. V. Niederhaus⁴
¹Surgery, Vanderbilt University, Nashville, TN, ²UNOS, Richmond, VA, ³Surgery, University of Minnesota, Minneapolis, MN, ⁴Surgery, University of Maryland, Baltimore, MD
*Purpose: In 2018, the OPTN board approved changes to kidney-pancreas (KP) waiting time criteria. KP candidates accrued waiting time if they were (1) on insulin…