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Articles tagged "Kidney"

  • 2022 American Transplant Congress

    Characterizing the Landscape of Cancer Risk Following HLA-Incompatible Living Donor Kidney Transplantation

    J. D. Motter1, K. Jackson1, K. Yu2, R. M. Pfeiffer2, A. Massie1, J. Garonzik-Wang3, D. Segev1, E. A. Engels2

    1Johns Hopkins University, Baltimore, MD, 2National Cancer Institute, Bethesda, MD, 3University of Wisconsin-Madison, Madison, WI

    *Purpose: Incompatible living donor kidney transplant recipients (ILDKTr) require desensitization to facilitate transplantation across donor-specific antibody (DSA); however, this substantial upfront immunosuppression may result in…
  • 2022 American Transplant Congress

    Incidence of De Novo Donor Specific Antibodies After Early Steroid Withdrawal in Kidney Transplant Recipients

    D. Majmundar, S. Karhadkar, A. Diamond, J. Au, C. Ruggia-Check

    Temple University Hospital, Philadelphia, PA

    *Purpose: Early steroid withdrawal (ESW) regimens may lead to the formation of de novo donor-specific antibodies (dnDSA) post-kidney transplant, which increases the risk of antibody-mediated…
  • 2022 American Transplant Congress

    Valganciclovir for the Prevention of CMV After Treatment of Rejection with Anti-Lymphocyte Depleting Antibodies in Kidney Transplant Recipients

    M. Mahoney, J. Nelson, E. Kincaide, R. Hall, H. Sweiss

    University Health, San Antonio, TX

    *Purpose: To evaluate efficacy and safety of valganciclovir for prevention of cytomegalovirus (CMV) after treatment of rejection with anti-lymphocyte depleting antibodies (ALA).*Methods: This single-center retrospective…
  • 2022 American Transplant Congress

    Surveillance of Donor-Derived Cell-Free DNA Throughout Treatment of Acute Rejection in Pediatric Renal Transplant Recipients

    K. A. Klein1, E. L. Kincaide1, M. Fei2, A. M. Bell2, M. Y. Arar3, D. Ranch3

    1Pharmacotherapy Education and Research Center, UT Health San Antonio, San Antonio, TX, 2CareDx, Inc., Brisbane, CA, 3Long School of Medicine, UT Health San Antonio, San Antonio, TX

    *Purpose: Donor-derived cell-free DNA (dd-cfDNA) is a dynamic plasma biomarker for allograft rejection with limited data in pediatric renal transplant recipients and few reports describing…
  • 2022 American Transplant Congress

    Mycotic Aneurysm of Transplant Renal Artery Successfully Treated with Arterial Conduit

    Y. Al-Salmay, B. Juengel, J. Kumar, P. Bachul, A. Perez-Guttierez, R. Barth, J. Fung, P. Witkowski

    University of Chicago, Chicago, IL

    *Purpose: Infection in the renal graft hilum may lead to mycotic aneurysm and life threatening bleeding, therefore it often warrants complete excision of the graft.…
  • 2022 American Transplant Congress

    RNA Sequencing Profiling of Pretransplant Blood Identified Variant Allele Specific Expression of Leukocyte Immunoglobulin-Like Receptors (LILRs) Genes Associated with Graft Loss in Kidney Transplant Recipients

    Z. Sun1, Z. Yi1, Z. Zhang1, P. Cravedi1, M. Menon2, B. Murphy1, S. Chen3, W. Zhang1

    1Icahn School of Medicine at Mount Sinai, New York City, NY, 2Yale University School of Medicine, New Heaven, CT, 3Methodist Hospital, Houston, TX

    *Purpose: The RNA sequencing has the possibility of detecting overall gene expression as well as allele-specific expression. Here, we reported a study of genome-wide allele…
  • 2022 American Transplant Congress

    Reduction in Opioid Discharge Prescribing for Kidney Transplant Recipients Through Implementation of a Standardized Opioid Prescribing Policy

    S. Fredrick1, K. Dokus2, J. Cooley1, A. Dulen3, J. Melaragno1

    1Pharmacy, University of Rochester Medical Center, Rochester, NY, 2Transplant Surgery, University of Rochester Medical Center, Rochester, NY, 3Wegmans School of Pharmacy, St. John Fisher College, Rochester, NY

    *Purpose: Diversion of unused opioid medications has contributed to the opioid epidemic, and opioid use after kidney transplantation has been shown to be a risk…
  • 2022 American Transplant Congress

    Revolutionizing Clinical Diagnostic Models for Acute Rejection Using Generative Adversarial Networks

    W. Yazar1, R. Nijor1, R. Sarwal1, N. Titzler1, M. Sarwal2, S. Ghosh1

    1Nephrosant, Brisbane, CA, 2NephroSant, Brisbane, CA

    *Purpose: Data heterogeneity, incompleteness and class-imbalance, hallmarks of real world healthcare data (RWHD), pose long-standing challenges to the accuracy of AI-based models. This research evaluates…
  • 2022 American Transplant Congress

    Kidney Allocation System Promotes Racial Equality Not Equity in Access to Deceased Donor Kidney Transplantation

    C. Killian1, B. Shelton1, P. MacLennan1, M. McLeod1, A. Carter1, R. Reed1, H. Qu1, B. Orandi1, V. Kumar1, D. Sawinski2, J. Locke1

    1University of Alabama at Birmingham, Birmingham, AL, 2Weill Cornell Medical College, New York City, NY

    *Purpose: While the 2014 Kidney Allocation System (KAS) reduced deceased donor kidney transplant (DDKT) racial disparities, candidates’ community-level vulnerability has not been considered. The purpose…
  • 2022 American Transplant Congress

    Dietary Sodium Intake And Blood Pressure In Living Kidney Donors (SPLID): Rationale And Design Of A Pilot Single-center Crossover Single-blind Randomized Controlled Trial

    E. Tantisattamo1, U. G. Reddy1, A. J. Ferrey1, H. Ichii2, D. C. Dafoe2, H. Moradi1, C. M. Rhee1, K. Kalantar-Zadeh1

    1Division of Nephrology, Hypertension and Kidney Transplantation, Department of Medicine, University of California Irvine School of Medicine, Orange, CA, 2Division of Kidney and Pancreas Transplantation, Department of Surgery, University of California Irvine School of Medicine, Orange, CA

    *Purpose: Since living kidney donors(LKD) are generally healthy and non-hypertensive individuals, non-pharmacologic interventions are likely to be an acceptable and practical approach to preventing hypertension(HTN).…
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