Articles tagged "Kidney transplantation"

2021 American Transplant Congress
Mortality from Fulminant Myocarditis in Multi-organ Transplant Recipient with Covid-19
K. Mahendraraj, I. Kim, T. Todo, T. Brennan, N. Nissen, K. Kosari, G. Voidonikolas, D. Ramzy
Transplant Surgery, Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: Novel coronavirus infection has been rarely described in multi-organ transplantation. This case highlights the poor prognosis associated with cardiac involvement by SARS-Cov-2 in transplantation,…
2021 American Transplant Congress
Kidney Transplantation Management and Decision Support System
A. Demirag¹, Y. Wu², J. Lamp², S. Holland¹, A. Routt², L. Feng²
¹Transplantation, University of Virginia Medical Cener, Charlottesville, VA, ²Computer Science Engineering Systems & Environment, University of Virginia, Charlottesville, VA
*Purpose: Coordinating the management of patients’ health statuses, tracking and scheduling testing, is a complicated process and involves a team of clinicians including transplant coordinators,…
2021 American Transplant Congress
Feasibility of a Virtual Renal Transplant Simulation Model for Surgical Trainees in the Covid Era
O. Eletta¹, S. Iacono¹, D. Walls¹, S. Puri², B. Perry¹, C. Anderson¹, M. J. Nguyen³, A. Bongu²
¹General Surgery, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, ²Transplant, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, ³Transplant Institute, Loma Linda University Medical Center, Loma Linda, CA
*Purpose: The COVID-19 pandemic and social distancing requirements has affected our resident education curriculum. We developed a virtual renal transplant simulation session to simulate renal…
2021 American Transplant Congress
Status of Kidney Allocation in Liver-kidney Transplants Before and After the UNOS/OPTN Policy
J. Oveyssi, M. Hussain, P. Homkrailas, S. Bunnapradist
Department of Internal Medicine: Division of Transplant Nephrology, UCLA, Los Angeles, CA
*Purpose: On August 10, 2017 the United Network for Organ Sharing (UNOS) enacted policies 9.7 and 8.5G to establish medical criteria for simultaneous liver-kidney (SLK)…
2021 American Transplant Congress
Drivers of Graft Failure in Pediatric Kidney Transplant Change Over Time
E. Benz¹, D. Schaubel², S. Amaral¹
¹Children's Hospital of Philadelphia, Philadelphia, PA, ²Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, Philadelphia, PA
*Purpose: Short-term pediatric kidney transplant outcomes have improved over time with advanced surgical techniques and better immunosuppression, but long-term graft outcomes remain suboptimal - concerning…
2021 American Transplant Congress
Impact of COVID-19 on Solid Organ Transplantation
E. Sampson¹, S. Hall², K. Robichaux³, A. Kumar², N. Kemmer⁴, J. Buggs⁵
¹Lake Erie College of Osteopathic Medicine, Tampa, FL, ²Morsani College of Medicine, University of South Florida, Tampa, FL, ³Honors College, University of South Florida, Tampa, FL, ⁴Transplant Hepatology, Tampa General Hospital, Tampa, FL, ⁵Transplant Surgery, Tampa General Hospital, Tampa, FL
*Purpose: Patterns of racial disparities have been identified throughout the history of American medicine. In December 2019, COVID-19 was first detected and has had a…
2021 American Transplant Congress
The Effect of Daratumumab (Dara, Humanized Anti-CD38 Monoclonal Antibody) on Immune Cells In Vitro and in a HLA-Sensitized Kidney Transplant Patient (HS KTx Pt) Desensitized (DES) with Dara
S. Ge¹, M. Chu¹, A. De Guzman¹, E. Ortiz¹, A. Vo², N. Ammerman², S. C. Jordan², M. Toyoda¹
¹Transplant Immunology Laboratory, Cedars Sinai Medical Center, Los Angeles, CA, ²Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, CA
*Purpose: Antibody-Mediated Rejection (ABMR), primarily mediated by B cells, plasma cells (PC) and antibodies (Ab), is an obstacle for successful transplantation in HS KTx Pts.…
2021 American Transplant Congress
Covid-19 Impact of the Pandemic Surge on Patients Waiting for Renal Transplantation at a Single New York City Transplant Center
G. Boyd, D. Tsapepas, R. Bonifacio, L. Brinkers, C. Brennan, A. Chang, M. Dalangin, L. Lowe, J. K. Mendoza, J. V. Mendoza, C. McNulty, M. Morris, M. Muttiah, K. Nickason, L. Ratner
Transplant, NYP - Columbia University Medical Center, New York, NY
*Purpose: There was a critical need to understand the impact that the COVID-19 pandemic had on our patients awaiting transplantation, including infection rates, morbidity, mortality,…
2021 American Transplant Congress
Sequential Analysis of Renal Allograft Rejection at Single Cell Resolution
T. Shi¹, C. Castro-Rojas¹, A. Burg¹, K. Roskin¹, J. Rush², B. Haraldsson², A. Shields³, R. Alloway³, E. Woodle³, D. Hildeman¹
¹Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Novartis Pharmaceuticals AG, Basel, Switzerland, ³University of Cincinnati Medical Center, Cincinnati, OH
*Purpose: Renal allograft anti-rejection therapies (corticosteroids (CCS) and anti-lymphocyte globulin) have been the primary treatment modalities for over six decades, yet little is known about…
2021 American Transplant Congress
Digital Spatial Mrna Profiling Reveals Distinct Endothelial Transcripts in Dsa+ and Dsa- Endarteritis in Kidney Allografts
K. Tomaszewski¹, M. Araujo Medina¹, A. Bruce¹, P. Divakar², R. Smith¹, T. Kawai³, R. Colvin¹, I. Rosales¹
¹Department of Pathology, Massachusetts General Hospital, Boston, MA, ²NanoString Technologies, Inc., Seattle, WA, ³Department of Surgery, Massachusetts General Hospital, Boston, MA
*Purpose: Renal allograft biopsy transcript analysis is typically performed by microarray, which lacks spatial resolution. We initiated a systematic program using the NanoString GeoMx® Digital…