Articles tagged "Kidney transplantation"

2021 American Transplant Congress
Development of Diagnosis Method of Acute Graft Rejection After Kidney Transplantation Using Metabolome Analysis by Liquid Biopsy Approach
H. Iwamoto¹, M. Sugimoto², O. Konno¹, I. Akashi³, M. Okihara¹, Y. Kihara¹, T. Ueno¹
¹Kidney Transplantation Surgery, Tokyo Medical University, Hachioji Medical Center, Tokyo, Japan, ²Research and Development Center for Minimally Invasive and Preemptive Medicine, Institute of Medi, Tokyo Medical University, Tokyo, Japan, ³Kidney transplantation Surgery, Tokyo Medical University, Hachioji Medical Center, Tokyo, Japan
*Purpose: Presently, a definitive diagnosis of organ dysfunction after transplantation (such as acute rejection) is dependent on conventional histopathological evaluation using an invasive biopsy procedure…
2021 American Transplant Congress
Atg16l-Dependent Autophagy Attenuates Procession of Renal Interstitial Fibrosis in Chronic Renal Graft Dysfunction via Regulating Tumor Necrosis Factor Alpha (tnf-α) Induced Endmt
Z. Gui, Z. Wang, Z. Han, J. Tao, X. Ju, R. Tan, M. Gu
The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
*Purpose: Chronic renal graft dysfunction is characterized by inflammation, tubular injury, and interstitial fibrosis. We have confirmed that endothelial-mesenchymal transition (EndMT) was one of important…
2021 American Transplant Congress
The Relationship Between Health Literacy and Adverse Outcomes After Kidney Transplantation
E. Lorenz, T. Petterson, C. Schinstock, W. Sanchez, K. Yost
Mayo Clinic, Rochester, MN
*Purpose: Limited health literacy has been associated with a decreased likelihood of listing for transplant and an increased risk of waitlist mortality among kidney transplant…
2021 American Transplant Congress
Pilot Study for the Use of Shortened Preemptive Therapy with Glecaprevir/pibrentasvir (g/p) and Ezetimibe in Hepatitis C Seronegative Solid Organ Transplant Recipients (Kidney and Heart) of Hepatitis C Viremic Donors
B. Aqel¹, H. Khamash², A. Moss³, D. E. Steidley⁴, R. C. Dickson¹
¹Gastroenterology and Hepatology, Mayo Clinic, Phoenix, AZ, ²Nephrology and Hypertension, Mayo Clinic, Phoenix, AZ, ³Transplant Surgery, Mayo Clinic, Phoenix, AZ, ⁴Cardiology, Mayo Clinic, Phoenix, AZ
*Purpose: This prospective study aims to assess the efficacy of preemptive therapy with eight days of a combination of direct-acting antivirals (DAAs) (Mavyret) (Pibrentasvir /Glecaprevir)…
2021 American Transplant Congress
Video Virtual Transplant Evaluation and Listing
V. Casingal¹, B. Thrasher², J. Brown², C. Fotiadis²
¹Department of Surgery, Atrium Health, Charlotte, NC, ²Department of Transplant, Atrium Health, Charlotte, NC
*Purpose: Due to the COVID-19 pandemic, many hospitals suspended in person evaluations of kidney transplants during the March-April time period of 2020. State and local…
2021 American Transplant Congress
Donor Kidney-Resident Macrophages Promote Allograft Inflammation and CD8 T Cell Response Post-Transplantation
A. Dangi¹, S. Yu², I. Husain¹, R. Geesala¹, X. Luo¹
¹Nephrology, Medicine, Duke University, Durham, NC, ²Division of Organ Transplantation, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
*Purpose: Kidney-resident macrophages play important roles in maintaining normal kidney function and promoting prompt repair following kidney injuries. Nevertheless, their fate and role in kidney…
2021 American Transplant Congress
Impact of Deceased Donor Mode of Death and Kidney Donor Profile Index on Baseline Donor Derived Cell Free DNA in Kidney Transplant Recipients
B. Chopra, A. Grazier, K. K. Sureshkumar
Allegheny Health Network, Pittsburgh, PA
*Purpose: Donor derived-cell free DNA (dd-cfDNA) is a novel serum biomarker available for earlier prediction of acute rejection in renal allograft. Baseline dd-cfDNA values are
2021 American Transplant Congress
Tru and Sure -A Tale of Two Cities! Can Allosure Predict and Enhance Trugraf Results?
Y. A. Qazi¹, W. Mon¹, S. Qazi², C. Choi¹, M. Smogorzewski¹
¹Keck Medical Center at USC, Los Angeles, CA, ²Keck Medical Center at USC, La Canada Flt, CA
*Purpose: With the introduction of Cell free DNA(cfDNA) technology in transplantation a few years ago, and a more recent addition of genomic testing with TruGraf…
2021 American Transplant Congress
Risk Factors Associated with Severe COVID19 Illness in Kidney Transplant Recipients
E. Abuhelaiqa, M. Alkadi, H. Tohid, R. Elidrisi, R. Abdul Rahiman, M. F. Elshirbeny, T. A. Ghonaimi, A. I. Hamad, A. Nauman, A. A Aziz, O. Fituri, M. Asim, M. A. Othman, H. Al-Malki
Hamad Medical Corporation, Doha, Qatar
*Purpose: COVID19 is an acute respiratory infection that is caused by the SARS-COV-2 that has been shown to be highly contagious and poses a significant…
2021 American Transplant Congress
COVID-19 Infection in Kidney versus Non-kidney Solid Organ Transplant Recipients: A Single Center Study
J. Schaenman¹, H. Byford², T. R. Grogan³, S. Fraschilla², K. Meneses⁴, J. C. Alejos⁵, M. Rivera⁶, S. Saab⁷
¹Infectious Diseases, UCLA, Los Angeles, CA, ²Transplant Administration, UCLA, Los Angeles, CA, ³Division of General Internal Medicine and Health Services Research, UCLA, Los Angeles, CA, ⁴Liver Transplantation, UCLA, Los Angeles, CA, ⁵Pediatric Heart Transplantation, UCLA, Los Angeles, CA, ⁶Pediatric Kidney Transplantation, UCLA, Los Angeles, CA, ⁷Liver Transplantation, David Geffen School of Medicine at UCLA, Los Angeles, CA
*Purpose: The COVID-19 pandemic has caused significant morbidity and mortality in patients around the world. A significant impact has been observed in immunocompromised patients such…