Articles tagged "Kidney transplantation"

2021 American Transplant Congress
Longitudinal Studies of Blood Donor-derived Cell Free DNA (dd-cfDNA) Show Predictable Rise at Time of BK Viremia or Viruria in Pediatric Kidney Transplant Recipients (PKTx)
R. Dandamudi¹, H. Gu¹, C. Goss¹, S. Federman², R. Woodward², S. Dholakia², L. Walther¹, V. Dharnidharka¹
¹Washington University in St Louis, St. Louis, MO, ²CareDx, Brisbane, CA
*Purpose: Blood levels of dd-cfDNA elevate in various forms of kidney transplant injury, most notably used for detecting potential acute rejection. A few adult studies,…
2021 American Transplant Congress
Combined Impact of Pre-sensitization and Delayed Graft Function on Allograft Rejection in Deceased Donor Kidney Transplantation: A Nationwide Cohort Study
H. Lee¹, Y. Park¹, T. Ban², S. Song³, S. Song⁴, J. Yang⁵, C. Ahn⁵, C. Yang¹, B. Chung¹
¹Division of Nephrology, Department of Internal Medicine, Seoul St. Mary’s hospital, Seoul, Korea, Republic of, ²Division of Nephrology, Department of Internal Medicine, Eunpyeong St. Mary’s hospital, Seoul, Korea, Republic of, ³Organ Transplantation Center and Department of Internal Medicine, Pusan National University Hospital, Pusan, Korea, Republic of, ⁴Department of Surgery, Ewha Womans University Medical Center, Seoul, Korea, Republic of, ⁵Department of Nephrology, Seoul National University Hospital, Seoul, Korea, Republic of
*Purpose: The aim of this study is to investigate whether or not delayed graft function (DGF) and pre-transplant sensitization has a synergistic adverse effect on…
2021 American Transplant Congress
Donor-Derived Cell-Free DNA as a Surrogate Marker for “Allograft Quiescence” After Kidney Transplantation
J. S. Bromberg¹, L. Bu², G. Gupta³, I. Moinuddin³, S. Anand⁴, A. Pai⁵, T. Alhamad⁶, V. Bowers⁷, S. Ghosh⁸, W. Tian⁸, E. Stites⁹
¹University of Maryland School of Medicine, Baltimore, MD, ²University of Minnesota, Minneapolis, MN, ³Virginia Commonwealth University, Richmond, VA, ⁴Intermountain Medical Center, Murray, UT, ⁵University of Texas McGovern Medical School, Houston, TX, ⁶Washington University in St. Louis, St. Louis, MO, ⁷Tampa General Hospital, Tampa, FL, ⁸CareDx, Brisbane, CA, ⁹University of Colorado, Aurora, CO
*Purpose: Donor-derived cell-free DNA (dd-cfDNA; AlloSure®) and the association with active rejection (AR) was described by Bloom et al, however subsequent insights have suggested this…
2021 American Transplant Congress
Donor CPR and Solid Organ Transplantation
E. Larsen¹, K. Cardoza², K. Robichaux³, A. Kumar¹, V. Bowers⁴, J. Buggs⁴
¹Morsani College of Medicine, University of South Florida, Tampa, FL, ²Honors College, University of Tampa, Tampa, FL, ³Honors College, University of South Florida, Tampa, FL, ⁴Transplant Surgery, Tampa General Hospital, Tampa, FL
*Purpose: In 2010, the American Heart Association and Emergency Cardiac Care (AHA ECC) set a 10-year impact goal of doubling cardiac arrest survival by 2020.…
2021 American Transplant Congress
Machine Learning Approaches for Post-transplant Kidney Outcome Prediction
H. Ghali¹, D. Won¹, S. Yoon¹, A. Friedman²
¹Systems Science and Industrial Engineering, SUNY Binghamton, Binghamton, NY, ²LiveOnNY, New York, NY
*Purpose: Determine a robust prediction model for kidney graft survival based on analyzing a combination of decisive factors such as donor and recipient characteristics, biopsy,…
2021 American Transplant Congress
Influence of Vitamin D Status on the Prognosis of Covid 19 in Patients with Kidney Transplant
J. Ugalde-Altamirano, I. Revuelta, A. Carrillo, M. Xipell, F. Cofan, N. Esforzado, E. Montagud, G. Piñeiro, A. Molina, P. Ventura, D. Cucchiari, F. Oppenheimer, F. Diekmann, J. Campistol, B. Bayes, J. Torregrosa
Nephrology, Hospital Clinic de Barcelona, Barcelona, Spain
*Purpose: The protective role of Vitamin D as an immunomodulator has been demonstrated in different pathologies included the viral etiology. This effect has been described…
2021 American Transplant Congress
Kidney Transplantation in Very Highly-Sensitized Patients with Maastricht Type III Non-heart-Beating Donors
F. Villanego¹, A. Mazuecos¹, L. Vigara¹, V. Lopez², G. Bernal³, A. Rodriguez-Benot⁴, M. de Gracia⁵, P. Castro⁶, A. Alvarez⁶
¹Department of Nephrology, Hospital Puerta del Mar, Cadiz, Spain, ²Department of Nephrology, Hospital Carlos Haya, Malaga, Spain, ³Department of Nephrology, Hospital Virgen del Rocio, Sevilla, Spain, ⁴Department of Nephrology, Hospital Reina Sofia, Cordoba, Spain, ⁵Department of Nephrology, Hospital Virgen de las Nieves, Granada, Spain, ⁶Andalusian Transplant Coordination, Sevilla, Spain
*Purpose: In 2012, a kidney transplant (KT) program for very highly-sensitized (VHS) patients (PRA ≥ 95%) based on virtual crossmatch began in Andalusia (Spanish region).…
2021 American Transplant Congress
Long Term Safety and Efficacy of Tocilizumab (anti-il6r, Tcz) Therapy in the Treatment of Refractory Chronic Antibody Mediated Rejection (cabmr) in 25 Pediatric Renal Transplant Recipients
M. Pearl¹, P. Weng¹, A. Dokras², H. Pizzo³, J. Garrison³, C. Butler¹, J. Q. Zhang¹, K. Lim³, E. Reed¹, I. Kim³, M. Haas³, X. Zhang³, R. Ettenger¹, S. Jordan³, D. Puliyanda³
¹Pediatric Nephrology, UCLA Medical Center, Los Angeles, CA, ²Pediatric Nephrology, UT South Western, Dallas, CA, ³Pediatric Nephrology, Cedars Sinai Medical Center, West Hollywood, CA
*Purpose: Development of de novo donor specific antibodies (DSA) post renal transplantation puts pediatric patients at risk for chronic Antibody Mediated Rejection (cABMR) and allograft…
2021 American Transplant Congress
Outcomes from High KDPI Kidneys Utilized for Dual Kidney Transplantation
J. Wagler¹, K. Mitchell², S. Ohara³, R. Heilman², S. K. Reddy², H. Khamash², C. Jadlowiec²
¹Mayo Clinic Arizona, Phoenix, AZ, ²Mayo Clinic, Phoenix, AZ, ³Valleywise Health General Surgery Residency Program, Phoenix, AZ
*Purpose: In light of the ongoing organ shortage, dual kidney transplantation (DKT), utilizing two adult kidneys from the same donor for one recipient, has been…
2021 American Transplant Congress
Kidney Paired Exchange in Children in the United-states
J. Hogan¹, A. G. Thomas², J. Verbesey³, D. L. Segev⁴
¹Transplant Research Center, Department of Surgery, Emory University, Atlanta, GA, ²Department of Epidemiology, University of North Carolina, Chapel Hill, NC, ³Department of Surgery, Medstar Georgetown Transplant Institute, Washington, DC, ⁴Department of Surgery, Johns Hopkins University, Baltimore, MD
*Purpose: Kidney paired exchange (KPE) plays an increasing role in the landscape of adult living donor transplant (LDTx) in the US. LDTx is the treatment…