Articles tagged "Kidney transplantation"

2021 American Transplant Congress
Immunosuppression Impacts Panel Reactive Antibody Status in Second Solid Organ Transplant Recipients – A Single Center Experience
J. Patel¹, S. Ali², M. L. Sanders¹, C. P. Thomas¹, D. Axelrod¹, M. Bilal³, E. H. Field³, S. Kuppachi¹
¹University of Iowa Hospitals & Clinics, Iowa city, IA, ²Louis A. Johnson VA Medical Center, Clarksburg, WV, ³Iowa City VA Health Care System, Iowa city, IA
*Purpose: Patients who require a second solid organ transplantation are significantly disadvantaged due to the event of sensitization due to the first transplant. We hypothesized…
2021 American Transplant Congress
Estimated GFR by Serum Myo-inositol, Valine, Creatinine, and Cystatin-c Outperforms Current CKD-epi Equations in Renal Transplant Recipients
J. W. Meeusen¹, F. Stammler², J. Lieske³, M. Grassi², M. Shah⁴, E. Schiffer²
¹Cardiovascular Laboratory Medicine, Mayo Clinic, Rochester, MA, ²Research and Development, Numares, Boston, MA, ³Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, ⁴Clinical Research, Numares, Boston, MA
*Purpose: Current estimated GFR (eGFR) equations using creatinine and/or cystatin C do no perform well in kidney transplant (KTx) recipients. Therefore, some large transplant programs…
2021 American Transplant Congress
Immune Response to Covid-19 in Kidney Transplant Waitlist Patients
P. T. Jindra¹, C. M. Foye¹, I. Sharf², A. Rana¹, T. N. Galvan¹, A. Awan¹, C. A. O'Mahony¹, B. V. Murthy¹
¹Baylor College of Medicine, Houston, TX, ²Baylor St. Luke's Medical Center, Houston, TX
*Purpose: The purpose of this study was to determine the effect of SARS-CoV-2 infection on the immune response in Kidney Transplant Waitlist Candidates (KTWC) and…
2021 American Transplant Congress
Survival Outcomes in Kidney Transplant Recipients Aged 18-60 Years by CMV Discordance Status: A Multivariable Analysis
A. Dinesh¹, T. Shaker¹, S. Jackson², S. Riad³, T. L. Pruett¹
¹Division of Transplantation, Department of Surgery, University of Minnesota, Minneapolis, MN, ²Biostatistics, Analytics Consulting Services- Solid Organ Transplant, M Health Fairview, Minneapolis, MN, ³Department of Medicine, University of Minnesota, Minneapolis, MN
*Purpose: Despite advances in CMV therapeutics, CMV infection can pose significant comorbidity after transplantation. We sought to examine the impact of high-risk CMV discordance in…
2021 American Transplant Congress
Belatacept Pharmacokinetics in Patients with and without Infection
A. Bickenbach¹, M. McGowan¹, B. Miyagawa², T. Mizuno², A. Shields³, A. Christianson¹, P. West-Thielke⁴, J. Leone⁵, E. Woodle¹, D. Kaufman⁶, A. Wiseman⁷, A. Vinks², R. Alloway¹
¹U Cincinnati, Cincinnati, OH, ²Cincinnati Children's Med Center, Cincinnati, OH, ³Christ Hospital, Cincinnati, OH, ⁴UIC, Chicago, IL, ⁵Tampa Gen, Tampa, FL, ⁶U Wisconsin, Madison, WI, ⁷Centura Transplant, Denver, CO
*Purpose: Two belatacept(BELA) fixed mg/kg dosing regimens, less intense(LI) and more intense(MI) were compared. The LI regimen was approved due to the higher risk profile…
2021 American Transplant Congress
Changes to Allocation of En Bloc Deceased Donor Kidneys to Low Epts Patients
A. Robinson¹, M. Pavlakis², V. Casingal³
¹United Network for Organ Sharing, Richmond, VA, ²Beth Israel Deaconess Medical Center, Boston, MA, ³Carolinas Medical Center, Charlotte, NC
*Purpose: The OPTN implemented a policy on September 5, 2019 standardizing en bloc deceased donor kidney allocation in order to efficiently place and utilize kidneys…
2021 American Transplant Congress
Excellent Outcomes of Kidney Transplantation from Hepatitis C Infected Donors
B. Rawashdeh, J. Dann, K. M. Marsh, A. Doddi, S. Rao, A. Agarwal
UVA Health System, University of Virginia, Charlottesville, VA
*Purpose: Utilization of Hepatitis C viremic (HCV D+) kidney donors in HCV naïve recipients has increased in the United States. While there are shorter waiting…
2021 American Transplant Congress
Identifying the Needs of Kidney Transplant Recipients That Can be Addressed by a Web-based Self-management Program
D. Massierer¹, R. Sapir-Pichhadze², V. Bouchard³, K. Dasgupta², N. Fernandez⁴, D. da Costa², S. Ahmed¹, M. Fortin⁵, R. Langevin⁶, N. Mayo¹, T. Janaudis-Ferreira¹
¹Faculty of Medicine- School of Physical and Occupational Therapy, McGill University, Montreal, QC, Canada, ²Centre for Outcomes Research and Evaluation (CORE), Research Institute of the McGill University Health Centre (RI-MUHC), Montreal, QC, Canada, ³CIUSSS du Saguenay-Lac-Saint-Jean, Chicoutimi, QC, Canada, ⁴Department of Family Medicine/Emergency Medicine, Université de Montreal, Montreal, QC, Canada, ⁵Department of Medicine, Université de Montreal, Montreal, QC, Canada, ⁶Canadian Donation and Transplantation Research Program (CDTRP), Edmonton, AB, Canada
*Purpose: Kidney transplantation improves the quality of life (QoL) of patients with end-stage renal disease, however, post-transplant recovery of physical health and other aspects of…
2021 American Transplant Congress
Sodium Zirconium Cyclosilicate Use in Kidney Transplant Recipients
K. J. Swanson, F. Aziz, S. Parajuli, M. Mohamed, D. A. Mandelbrot, A. Djamali, N. Garg
University of Wisconsin-Madison, Madison, WI
*Purpose: Hyperkalemia is a common problem experienced by kidney transplant recipients (KTR)s. New strategies to treat hyperkalemia are now available. KTRs often require medications that…
2021 American Transplant Congress
Tolerability of De Novo and Conversion Belatacept Regimens in Kidney Transplantation
T. Le¹, J. Shoji², J. Phillips¹, D. Quan¹
¹Pharmaceutical Services, UCSF Medical Center, San Francisco, CA, ²Transplant Nephrology, UCSF Medical Center, San Francisco, CA
*Purpose: Belatacept, a selective T lymphocyte co-stimulation blocker, has been shown to be a safe and effective maintenance therapy for immunosuppression. We investigated the long-term…