Articles tagged "Kidney transplantation"

2021 American Transplant Congress
Genetic versus Self-reported African Ancestry and Kidney Allograft Outcome: Analysis of Two Large Multiethnic Urban Transplant Cohorts
F. Zanoni¹, D. Neugut¹, S. Mohan¹, A. Gharavi¹, B. Keating², K. Kiryluk¹
¹Department of Medicine, Division of Nephrology, Columbia University, New York, NY, ²Department of Surgery, Division of Transplantation, University of Pennsylvania, Philadelphia, PA
*Purpose: African-American (AA) kidney transplant recipients (KTx) have higher risk of rejection and failure. However, it is unknown to what extent the inferior outcomes in…
2021 American Transplant Congress
Panic in the Pandemic: A Medical Decision Analysis Examining When Kidney Transplant Programs Should Close
A. J. Vinson¹, B. Kiberd², K. Tennankore¹
¹Nova Scotia Health Authority Division of Nephrology, Departm, Halifax, NS, Canada, ²Dalhousie University, Halifax, NS, Canada
*Purpose: Pandemics greatly interfere with overall health care delivery as resources are diverted to combat the crisis. Kidney transplantation programs were closed temporarily during the…
2021 American Transplant Congress
Systematic Screening of Kidney Transplant Patients Points Towards Deficits in Neutralizing Antibody Capacity Against Sars-cov-2
V. Wijtvliet¹, K. K. Ariën², J. Mariën², B. Peeters³, R. Hellemans⁴, A. Massart⁴, S. Van Hees¹, P. Moons⁵, H. Theeten⁶, P. Van Damme⁶, H. Goossens⁷, B. Y. De Winter¹, K. J. Ledeganck¹, D. Abramowicz⁴
¹Laboratory of Experimental Medicine and Pediatrics, University of Antwerp, Antwerp, Belgium, ²Department of Biomedical Sciences, Institute of Tropical Medicine and University of Antwerp, Antwerp, Belgium, ³Department of Laboratory Medicine, Antwerp University Hospital, Antwerp, Belgium, ⁴Department of Nephrology and Hypertension, Antwerp University Hospital, Antwerp, Belgium, ⁵Biobank, Antwerp University Hospital, Antwerp, Belgium, ⁶Centre for the Evaluation of Vaccination, Vaccine and Infectious Disease Institute, University of Antwerp, Antwerp, Belgium, ⁷Department of Medical Microbiology, Vaccine & Infectious Disease Institute, University of Antwerp, Antwerp, Belgium
*Purpose: The majority of kidney transplant recipients (KTR) is able to develop SARS-CoV-2 antibodies (Abs). Little is known about the virus neutralizing capacity of these…
2021 American Transplant Congress
Outcomes of Kidney Transplantation in Patients with Prosthetic Heart Valves
H. Ouahmi
Nephrology, Dialysis, Transplantation, Nice University Hospital, Nice, France
*Purpose: Due to the aging of the population, a growing number of patients with end-stage kidney disease (ESKD) require cardiac valve replacement. As a consequence,…
2021 American Transplant Congress
Mortality, Risk Factors, and Treatment of Covid-19 Infection in Solid Organ Transplants: A Systematic Review and Meta-analysis
S. Yin, T. Song, Q. Zhong, T. Lin
Urology Institute and Organ Transplantation Center, West China Hospital, Chengdu, China
*Purpose: Outcomes for solid organ transplants (SOT) with COVID-19 have not been summarized, and prognostic factors for COVID-19 in SOT patients are not well established…
2021 American Transplant Congress
Impact of High-Risk EBV Discordance Status on Survival Outcomes in Kidney Transplant Recipients: A Multivariable Analysis
A. Dinesh¹, S. Jackson², T. L. Pruett¹, S. Riad³
¹Division of Transplantation, Department of Surgery, University of Minnesota, Minneapolis, MN, ²Biostatistics, Analytics Consulting Services- Solid Organ Transplant, M Health Fairview, Minneapolis, MN, ³Department of Medicine, University of Minnesota, Minneapolis, MN
*Purpose: High-risk EBV discordance has been linked to Post-Transplant Lymphoproliferative Disorder (PTLD) after kidney transplantation; however, the impact on recipient and graft survival is under-reported.…
2021 American Transplant Congress
Effect of Multi-Organ Transplant Allocation on Pediatric Kidney Waitlist Candidates
D. Shepherd, R. M. Engen
Pediatric Nephrology, Ann & Robert H. Lurie Children's Hospital, Chicago, IL
*Purpose: Multi-Organ Transplants (MOTs) have variable allocation policies and often take precedence over other waitlist candidates. Lack of defined MOT guidelines divert kidneys to MOT…
2021 American Transplant Congress
Development of Diagnosis Method of Acute Graft Rejection After Kidney Transplantation Using Metabolome Analysis by Liquid Biopsy Approach
H. Iwamoto¹, M. Sugimoto², O. Konno¹, I. Akashi³, M. Okihara¹, Y. Kihara¹, T. Ueno¹
¹Kidney Transplantation Surgery, Tokyo Medical University, Hachioji Medical Center, Tokyo, Japan, ²Research and Development Center for Minimally Invasive and Preemptive Medicine, Institute of Medi, Tokyo Medical University, Tokyo, Japan, ³Kidney transplantation Surgery, Tokyo Medical University, Hachioji Medical Center, Tokyo, Japan
*Purpose: Presently, a definitive diagnosis of organ dysfunction after transplantation (such as acute rejection) is dependent on conventional histopathological evaluation using an invasive biopsy procedure…
2021 American Transplant Congress
Atg16l-Dependent Autophagy Attenuates Procession of Renal Interstitial Fibrosis in Chronic Renal Graft Dysfunction via Regulating Tumor Necrosis Factor Alpha (tnf-α) Induced Endmt
Z. Gui, Z. Wang, Z. Han, J. Tao, X. Ju, R. Tan, M. Gu
The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
*Purpose: Chronic renal graft dysfunction is characterized by inflammation, tubular injury, and interstitial fibrosis. We have confirmed that endothelial-mesenchymal transition (EndMT) was one of important…
2021 American Transplant Congress
The Relationship Between Health Literacy and Adverse Outcomes After Kidney Transplantation
E. Lorenz, T. Petterson, C. Schinstock, W. Sanchez, K. Yost
Mayo Clinic, Rochester, MN
*Purpose: Limited health literacy has been associated with a decreased likelihood of listing for transplant and an increased risk of waitlist mortality among kidney transplant…