ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2021 American Transplant Congress

    Needs of People with Kidney Transplantation During the Covid 19 Pandemic and Its Confinement, and the Role of Communication Technologies Through the “Patient Experience”

    I. Revuelta1, E. Palou2, R. Scandurra3, F. Oppenheimer1, F. Diekmann1, J. Escarrabill2, B. Bayés1

    1Department of Nephrology and Kidney Transplant, Hospital Clinic, Barcelona, Spain, 2Chronic care program and patient experience, Hospital Clinic, Barcelona, Spain, 3Department of Statistics, Universidad Autónoma de Barcelona, Barcelona, Spain

    *Purpose: During the COVID-19 pandemic, healthcare services have focused on the care of acute processes and there is a risk of not meeting the needs…
  • 2021 American Transplant Congress

    Bamlanivimab for Covid-19 in Kidney Transplant Patients

    M. Y. Jan, S. El-Sayegh, M. S. Yaqub, D. P. Mishler, O. Adebiyi, M. D. Anderson, T. E. Taber, A. Sharfuddin

    Nephrology, Indiana University School of Medicine, Indianapolis, IN

    *Purpose: Treatment options for patients with COVID 19 have limited efficacy in reducing severity and duration of viral symptoms as well as progression to severe…
  • 2021 American Transplant Congress

    Construction of a Waiting Time Predictive Model for Kidney Transplant with Deceased Donor in the State of São Paulo

    J. Silva1, M. Contti1, M. Valiatti1, H. Nga1, G. Santos1, M. Perosa2, G. Ferreira3, L. Modelli de Andrade1

    1UNESP, Botucatu, Brazil, 2Hospital Leforte, São Paulo, Brazil, 3Santa Casa de Juiz de Fora, Juiz de Fora, Brazil

    *Purpose: Chronic kidney disease is an important public health problem and kidney transplant is the therapy of choice when possible. The transplant system in the…
  • 2021 American Transplant Congress

    Peripheral Blood Inflammatory Chemokines Uncover Rejection in the Absence of Histological Lesions

    E. Van Loon1, T. Barba2, B. Lamarthée1, A. Senev1, O. Thaunat2, D. Schols3, M. Naesens1

    1Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium, 2Department of Transplantation, Nephrology and Clinical Immunology, Edouard Herriot Hospital Lyon, Lyon, France, 3Laboratory of Virology and Chemotherapy, KU Leuven, Leuven, Belgium

    *Purpose: Cytokines and chemokines play a critical role in the pathophysiology of allograft rejection, but the relation of peripheral blood cytokine expression profiles to clinical…
  • 2021 American Transplant Congress

    Outcomes of Kidney Transplant Recipients (KTRs) Comparing Brain Dead Donors’ vs Donation After Cardiac Death Stratified by KDPI, Focus on Marginal Kidneys: A UNOS Database Analysis

    B. Chopra1, K. K. Sureshkumar1, D. Rajasundaram2, E. C. Rodrigo3

    1Allegheny Health Network, Pittsburgh, PA, 2UPMC, Pittsburgh, PA, 3University Hospital Marqués de Valdecilla, Santander, Spain

    *Purpose: In deceased donor kidney transplantation (DDKT), donation after cardiac death (DCD) is associated with increased cytokine release and renal tubular injury with consequent increase…
  • 2021 American Transplant Congress

    The Benefits of Sharing Non-Directed Donors Nationally Through Paired Exchange

    J. Verbesey1, A. G. Thomas2, A. D. Waterman3, J. Vucci1, G. Vranic1, A. Gilbert1, S. Ghasemian1, M. Cooper1

    1Georgetown University Hospital, Washington, DC, 2Johns Hopkins University School of Medicine, Baltimore, MD, 3UCLA, Los Angeles, CA

    *Purpose: Non-directed donors (NDDs) are a valuable resource that can “unlock” incompatible transplants. Recent advances in paired kidney exchange (PKE) suggest that NDDs may facilitate…
  • 2021 American Transplant Congress

    Risk Stratification of Kidney Transplant Patients According to the Different Level of HLA-DQ Disparities

    A. Senev1, A. R. Tambur2, M. Naesens1

    1Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium, 2Northwestern University, Chicago, IL

    *Purpose: It is becoming clear that de novo donor-specific antibodies (dnDSA) against HLA-DQ are the most prevalent and the leading cause of chronic antibody-mediated rejection…
  • 2021 American Transplant Congress

    Donor-Derived Cell-Free DNA Levels Risk-Stratify Polyoma BK Viremia and Associated Clinical Events After Kidney Transplantation – Preliminary Results from ADMIRAL Study

    A. Pai1, L. Bu2, J. S. Bromberg3, G. Gupta4, I. Moinuddin4, T. Alhamad5, V. Bowers6, S. Ghosh7, W. Tian7, E. Stites8, S. Anand9

    1University of Texas McGovern Medical School, Houston, TX, 2University of Minnesota, Minneapolis, MN, 3University of Maryland School of Medicine, Baltimore, MD, 4Virginia Commonwealth University, Richmond, VA, 5Washington University in St. Louis, St. Louis, MO, 6Tampa General Hospital, Tampa, FL, 7CareDx, Brisbane, CA, 8University of Colorado, Aurora, CO, 9Intermountain Medical Center, Murray, UT

    *Purpose: The threshold of 10,000 copies for blood Quant BK PCR has been used as a surrogate for BK nephropathy (BKN) in kidney transplant recipients…
  • 2021 American Transplant Congress

    Extreme Phenotype Sampling and Next Generation Sequencing to Identify Genetic Variants Associated with Tacrolimus Metabolism in African American Kidney Transplant Recipients

    C. R. Dorr1, B. Guo2, B. Wu2, J. Abrahante2, D. Schladt3, R. Remmel2, W. Guan2, A. Muthusamy3, G. Onyeaghala3, N. Pankratz2, A. Matas2, R. Mannon4, W. Oetting2, P. Jacobson2, A. K. Israni3

    1Hennepin Healthcare Research Institute, Minneapolis, MN, 2University of Minnesota, Minneapolis, MN, 3Nephrology, Hennepin Healthcare Research Institute, Minneapolis, MN, 4University of Nebraska Medical Center, Omaha, NE

    *Purpose: Tacrolimus (TAC) pharmacogenomics studies identified common genetic variants that alter TAC troughs suggesting strategic dosing for specific populations. Common variants and clinical factors explain…
  • 2021 American Transplant Congress

    Belatacept and Carfilzomib-based Treatment of Active Antibody-mediated Rejection in a Sensitized Nonhuman Primate Model

    J. Kwun1, R. Schmitz1, M. Manook1, Z. Fitch1, D. Olaso1, A. Choi1, J. Yoon1, Y. Bae1, J. Lambris2, S. Knechtle1

    1Surgery, Duke University, Durham, NC, 2Pathology & Laboratory Medicine, University of Pennsylvania, Philadelphia, PA

    *Purpose: One third of sensitized, HLA-incompatible transplant recipients experience antibody-mediated rejection (AMR) with limited effective treatment options. We tested a novel treatment strategy for AMR…
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