ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2021 American Transplant Congress

    Belatacept Exposure Not Associated With Rejection. Can Doses be Lowered without Compromising Efficacy?

    M. McGowan1, A. Bickenbach1, B. Miyagawa2, A. Christianson1, T. Mizuno2, P. West-Thielke3, J. Leone4, E. Woodle1, D. Kaufman5, A. Wiseman6, A. Matas7, A. Vinks2, R. Alloway1

    1U Cincinnati, Cincinnati, OH, 2Cincinnati Children's Med Center, Cincinnati, OH, 3U Illinois, Chicago, IL, 4Tampa Gen, Tampa, FL, 5U Wisconsin, Madison, OH, 6Centura Transplant, Denver, CO, 7U Minnesota, Minneapolis, MN

    *Purpose: Phase 1 and 2 belatacept(BELA) pharmacokinetic(PK) studies informed dosing in phase 3 studies. PK data from these studies revealed higher BELA troughs on Day…
  • 2021 American Transplant Congress

    Impact of a Latinx Kidney Transplant Clinic

    P. Serrano Rodriguez

    Abdominal Transplant Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC

    *Purpose: To evaluate the impact of a Latinx clinic in our institution. With a growing increase of end stage renal disease (ESRD)in the Latino population…
  • 2021 American Transplant Congress

    Novel Mixed Lymphocyte Reaction Monitoring System That Predicts Chronic Antibody- Mediated Rejection in Kidney Transplant Recipients

    N. Iwahara1, K. Hotta1, T. Tanabe1, D. Iwami2, Y. Takada3, H. Higuchi1, H. Sasaki3, H. Harada3, N. Shinohara1

    1Hokkaido Univercity, Sapporo, Japan, 2Jichi Medical University, Shimotsuke, Japan, 3Sapporo City General Hospital, Sapporo, Japan

    *Purpose: Chronic active antibody-mediated rejection (CAAMR) induced by de novo donor-specific antibodies (DSA) is the main cause of graft loss in the long-term. Currently, there…
  • 2021 American Transplant Congress

    Outcomes of Kidney Transplantation from Hepatitis C Virus (HCV) Infected Donors Stratified by Recipient HCV Serostatus: A Mate Kidney Analysis

    K. K. Sureshkumar1, B. Chopra1, R. L. McGill2

    1Nephrology and Hypertension, Allegheny General Hospital, Pittsburgh, PA, 2Nephrology, University of Chicago, Chicago, IL

    *Purpose: Kidneys from donors infected with hepatitis C virus (HCV) are increasingly used for transplantation into HCV positive (+) recipients historically and into HCV negative…
  • 2021 American Transplant Congress

    Prevalence of Hepatitis E Virus Infection in Solid Organ Transplant Recipients: A Systematic Review and Meta-analysis

    P. Hansrivijit1, A. Trongtorsak2, B. Boonpheng3, C. Thongprayoon4, W. Cheungpasitporn4

    1Department of Internal Medicine, UPMC Pinnacle, Harrisburg, PA, 2Department of Internal Medicine, Amita Health Saint Francis Hospital, Evanston, IL, 3Division of Nephrology, David Geffen School of Medicine, University of California, Los Angeles, CA, 4Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN

    *Purpose: Hepatitis E virus (HEV) infection is an underdiagnosed disease due to the use of serological assays with low sensitivity. Although most patients with HEV…
  • 2021 American Transplant Congress

    Iguratimod Prevents Antibody-mediated Rejection by Regulating Germinal Center Formation and Antibody Production

    H. Zhang, A. Chandraker, P. Sage, N. Murakami

    Transplantation Research Center, Brigham and Women's Hospital, Boston, MA

    *Purpose: Antibody-mediated rejection (ABMR) is a major cause of chronic renal allograft failure without effective treatment, and developing a novel therapy is an urgent need.…
  • 2021 American Transplant Congress

    Biomarkers of Kidney Injury and Repair in Expanded-Criteria Deceased Donor Kidney Transplant Recipients: A Prospective Study

    A. Al Jurdi1, O. Efe1, B. Aoyama2, M. Lima2, H. Silva2, I. Schmidt3, S. Waikar3, V. Sabbisetti4, L. V. Riella1

    1Center for Transplantation Sciences, Massachusetts General Hospital, Charlestown, MA, 2Escola Paulista de Medicina, UNIFESP, São Paulo, Brazil, 3Boston Medical Center, Boston, MA, 4Brigham and Women’s Hospital, Boston, MA

    *Purpose: Expanded-criteria donor (ECD) kidney transplants are at higher risk of kidney injury. Biomarkers that better predict short and long-term outcomes in ECD kidney transplant…
  • 2021 American Transplant Congress

    Does the Timing of Subclinical Acute Rejection After Kidney Transplant Matter?

    P. Portocarrero1, S. Park2, K. Guo3, L. Zhao3, J. Friedewald2

    1Nephrology, Northwestern University, Chicago, IL, 2Transplant Nephrology, Northwestern University, Chicago, IL, 3Feinberg School of Medicine, Northwestern University, Chicago, IL

    *Purpose: We hypothesized that the timing of subclinical acute rejection (subAR) diagnosed with biopsy, gene expression profile or donor-derived cell-free DNA is associated with poor…
  • 2021 American Transplant Congress

    Impact of Rejection in Pediatric and Young Adult Kidney Transplant Recipients on the Use of Mental Health Resources

    E. Ruzicka1, E. Lyons2, C. Naclerio2, A. Sikora2, K. McKinnon2, E. Blanchette2, M. Chandran2, M. Bock2, E. Christofferson2

    1Children's Hospital Colorado, Aurora, CO, 2University of Colorado, Aurora, CO

    *Purpose: Allograft rejection often results in increased hospital and medical resource utilization. Pediatric kidney transplant recipients (KTR) are at risk for psychosocial stressors, nonadherence to…
  • 2021 American Transplant Congress

    Seroprevalence of SARS-CoV-2 Antibodies in Transplant Recipients in a Croatian Transplant Center

    A. Mrzljak1, Z. Jurekovic1, J. Pavicic Saric2, L. Antolasic3, L. Milasincic3, I. Tabain3, T. Vilibic Cavlek3

    1Department of Internal Medicine, Merkur University Hospital, Zagreb, Croatia, 2Department of Anesthesiology, Merkur University Hospital, Zagreb, Croatia, 3Department of Microbiology, Croatian Institute of Public Health, Zagreb, Croatia

    *Purpose: In Croatia, the first case of coronavirus disease (COVID-19) has been reported on 25 February 2020; however, the COVID-19 seroprevalence in the liver (LTR)…
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