Articles tagged "Kidney transplantation"

2021 American Transplant Congress
Coexistence of BKPyV Lytic Infection and Viral Integration in the Development of BKPyV Diseases After Renal Transplantation
S. Yan¹, Y. Wang¹, Y. Liu¹, W. Deng¹, Z. Yan¹, J. Xu¹, C. Wu², Y. Miao¹
¹Department of Organ Transplantation, Nanfang Hospital, Southern Medical University, Guangzhou, China, ²Departments of Urology & Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA
*Purpose: To understand the role of BK Polyomavirus (BKPyV) infection and integration in the pathogenesis of BKPyV-associated diseases.*Methods: Sixteen patients with BKPyV-associated diseases were included,…
2021 American Transplant Congress
Associations of Mammalian Target of Rapamycin Inhibitors with Post-Transplant Malignancies and All-Cause Mortality: Cause-Specific Competing Risks and Composite Outcomes Analyses
A. H. Santos¹, E. Bueno¹, M. A. Leghrouz¹, W. Xuerong²
¹University of Florida, Gainesville, FL, ²University of Rhode Island, Kingston, RI
*Purpose: We investigated the outcomes of malignancies and mortality associated with mammalian target of rapamycin inhibitor (MTORI) regimens in adult kidney transplant (KT) recipients (KTRs).*Methods:…
2021 American Transplant Congress
Interruption of Notch Signaling via Blockade of Delta-Like Ligand 4 Prevents Co-Stimulation Blockade Resistant Allograft Rejection
A. J. Matar, B. P. Lovasik, Y. Dong, D. A. Faber, J. Habib, C. Breeden, J. Regenold, A. Ghosh, A. Stephenson, W. H. Kitchens, A. B. Adams
Emory University Department of Surgery, Atlanta, GA
*Purpose: Co-stimulation blockade (CoB) has emerged as a promising immunosuppression strategy with the advent of Belatacept, a novel CTLA4-Ig fusion protein that blocks CD28-mediated T…
2021 American Transplant Congress
Noninferiority Outcomes Among Undocumented Immigrant Kidney Transplant Recipients in California
H. Ichii¹, N. Eguchi¹, E. Tantisattamo², U. Reddy², A. Ferrey², D. Dafoe¹
¹Surgery, University of California Irvine, Orange, CA, ²Medicine, University of California Irvine, Orange, CA
*Purpose: There are over 2 million undocumented immigrants (UI) in California, where currently, all individuals regardless of immigration status have equal access to kidney transplant(KT).…
2021 American Transplant Congress
A New Triage-based Approach to Managing Transplant Referrals
H. L. Walther
Division of Kidney & Pancreas Transplantation, UCI Health, Orange, CA
*Purpose: To develop and implement a novel triage-based approach to the management of referrals for kidney transplant evaluation*Methods: The transplant nurse coordinator dedicated to referral…
2021 American Transplant Congress
HLA Mismatching and Subclinical Inflammation: An Association to be Considered in Kidney Transplant Patients with Low Immunological Risk
T. Vazquez-Sanchez¹, J. Alonso-Titos¹, P. Ruiz-Esteban¹, A. Caballero², M. Leon³, V. Lopez¹, E. Sola¹, D. Hernández¹
¹Nephrology, Instituto de Investigación Biomédica de Málaga (IBIMA). Hospital Universitario Regional de Málaga and University of Málaga. REDinREN (RD16/0009/0006). Málaga. (Spain), Málaga, Spain, ²Immunology, Instituto de Investigación Biomédica de Málaga (IBIMA). Hospital Universitario Regional de Málaga and University of Málaga. REDinREN (RD16/0009/0006). Málaga. (Spain), Málaga, Spain, ³Pathology, Instituto de Investigación Biomédica de Málaga (IBIMA). Hospital Universitario Regional de Málaga and University of Málaga. REDinREN (RD16/0009/0006). Málaga. (Spain), Málaga, Spain
*Purpose: Subclinical inflammation (SCI) (
2021 American Transplant Congress
The Assesment of Pre-transplant Donor-reactive IL-21 Producing T Cells as a Tool to Identify Patients at Risk for Acute Rejection
A. Mendoza Rojas¹, T. van Gelder², R. de Kuiper¹, D. Reijerkerk¹, M. C. Clahsen-van Groningen³, D. A. Hesselink¹, C. C. Baan¹, N. M. van Besouw¹
¹Internal Medicine, Neprology & Transplantation, Erasmus Medical Center, Rotterdam, Netherlands, ²Department of Clinical Pharmacy & Toxicology, Leiden University Medical Center, Leiden, Netherlands, ³Internal Medicine, Pathology, Erasmus Medical Center, Rotterdam, Netherlands
*Purpose: The measurement of panel-reactive antibodies (PRA) has proven valuable in the transplant setting but it does not account for the presence of donor-reactive memory…
2021 American Transplant Congress
Evaluation of Serum Klotho Levels at Early Kidney Post-Transplant
T. Vazquez-Sanchez¹, J. Alonso-Titos¹, M. Sánchez-Niño², E. Sola¹, M. Leon³, V. Lopez¹, P. Ruiz-Esteban¹, E. Porrini⁴, A. Ortiz⁵, D. Hernández¹
¹Nephrology, Instituto de Investigación Biomédica de Málaga (IBIMA). Hospital Universitario Regional de Málaga and University of Málaga. REDinREN (RD16/0009/0006). Málaga. (Spain), Malaga, Spain, ²Nephrology, Instituto de InvestigaciónSanitaria de la FundaciónJiménez Díaz,UniversidadAutónoma de Madrid. REDINREN, Madrid, Spain, ³Pathology, Instituto de Investigación Biomédica de Málaga (IBIMA). Hospital Universitario Regional de Málaga and University of Málaga. REDinREN (RD16/0009/0006). Málaga. (Spain), Malaga, Spain, ⁴Nephrology, Hospital Universitario de Canarias, CIBICAN, Universidadde laLaguna, REDinREN (RD16/0009/0031) Tenerife e Instituto Reina Sofía de Investigación Renal (IRSIN), Malaga, Spain, ⁵Nephrology, Instituto de InvestigaciónSanitaria de la FundaciónJiménez Díaz,UniversidadAutónoma de Madrid. REDINREN, Malaga, Spain
*Purpose: Klotho expression is lowered in patients with chronic kidney disease (CKD). After kidney transplant (KT), serum Klotho levels could be significantly increased compared to…
2021 American Transplant Congress
Observational Study of the Clinical Characteristics and Short-term Outcomes of Kidney Transplant Recipients Diagnosed with Coronavirus-19 Infection (sars-cov2) Requiring Hospitalization in New Orleans
S. Giusti¹, S. Chazin², P. Vaitla³, K. Atiemo⁴, M. Atari¹, A. Paramesh⁴, H. Jeon⁴, A. Vijay⁴, A. Torres⁵, M. Killackey⁴, R. Thimmisetty⁶, J. Garces⁶
¹Tulane University Section of Nephrology & Hypertension, New Orleans, LA, ²Tulane University School of Medicine, New Orleans, LA, ³University of Mississippi Medical Center, Jackson, MS, ⁴Tulane Transplant Institute, New Orleans, LA, ⁵Ochsner Medical Center, New Orleans, LA, ⁶Ochsner Multi-Organ Transplant Institute, New Orleans, LA
*Purpose: Kidney transplant recipients are at increased risk of severe disease and death caused by Coronavirus-19 infection. The role of immunosuppressive medications in the clinical…
2021 American Transplant Congress
Methenamine for the Prevention of Recurrent UTIs Post-Renal Transplant
A. Bigness¹, S. Mohamed², S. Mandala¹, N. Khodieva², K. Robichaux³, H. Mohammed¹, J. Buggs⁴, A. Kumar¹, A. Brueckner⁵, L. Bowman⁵
¹Morsani College of Medicine, University of South Florida, Tampa, FL, ²College of Public Health, University of South Florida, Tampa, FL, ³Honors College, University of South Florida, Tampa, FL, ⁴Transplant Surgery, Tampa General Hospital, Tampa, FL, ⁵Department of Pharmacology, Tampa General Hospital, Tampa, FL
*Purpose: Urinary tract infections (UTIs) are a highly prevalent postoperative complication in kidney transplant recipients (KTRs), occurring in approximately 34% of patients. The common method…