Articles tagged "Kidney transplantation"

2021 American Transplant Congress
Blood Type A2/a2b to B Renal Transplantation: A Single Center Retrospective Cohort Study
V. S. Tatapudi, N. Alnazari, R. Chand, N. M. Ali, B. E. Lonze, R. A. Montgomery
NYU Langone Transplant Institute, NYU Langone Health, New York, NY
*Purpose: Blood type B candidates on the deceased donor kidney waitlist have a lower transplantation rate and longer wait time than candidates of other blood…
2021 American Transplant Congress
Increased T Cell Cross-dressing in Accepted Kidney Allografts
Q. Yuan¹, S. Hong², E. Szuter², I. Rosales², Y. Zhao², B. Gonzalez-Nolasco², G. Benichou², P. Russell², J. Madsen², R. Colvin², A. Alessandrini²
¹Massachusetts General Hospital/Chinese PLA General Hospital, Boston, MA, ²Massachusetts General Hospital, Boston, MA
*Purpose: Kidney allografts transplanted across certain mouse strain combinations (e.g. DBA/2 to B6) develop tolerance while other combinations do not (e.g. B6 to DBA/2). We…
2021 American Transplant Congress
Risk Classification Models for Kidney Graft Failure
M. G. Naik¹, K. Budde¹, D. Telmo Neves²
¹Medical Department, Division of Nephrology and Internal Intensive Care Medicine, Charité, Berlin, Germany, ²Intelligent Analytics for Massive Data, German Research Center for Artificial Intelligence, Berlin, Germany
*Purpose: Longterm graft survival after kidney transplantation is stagnant over the last decades. An individual risk assessment for graft failure is needed. In our project…
2021 American Transplant Congress
Early Transplant Education Increases CKD 3-5 Patients’ Knowledge and Informed Decision-Making About Chronic Kidney Disease and Living Donor Kidney Transplant
A. D. Waterman¹, S. H. Kawakita², B. Dub³, Y. A. Iraheta¹, A. L. Murillo², T. Menser⁴, B. Mittman³
¹UCLA David Geffen School of Medicine, Los Angeles, CA, ²Terasaki Institute, Los Angeles, CA, ³Research and Evaluation, Kaiser Permanente, Pasadena, CA, ⁴The Houston Methodist Research Institute, Houston, CA
*Purpose: Early education about chronic kidney disease (CKD) and living donor kidney transplant (LDKT) outside of transplant centers is inconsistent, with patients in CKD 3…
2021 American Transplant Congress
Frequency and Types of Pharmacist Interventions and Risk Assessments Occurring During the 12-Month Transafe Rx Randomized Controlled Trial
H. M. Gonzales, J. N. Fleming, D. J. Taber
MUSC, Charleston, SC
*Purpose: Clinical pharmacists have unique education and training to identify and mitigate medication (med) safety issues in high-risk populations, such as kidney transplant (KTX). The…
2021 American Transplant Congress
Value of a Personal Systems Approach in Improving Medication Adherence in Adult Kidney Transplant Patients: A Cost-effectiveness Analysis of the MAGIC Randomized Clinical Trial
M. R. Wakefield¹, M. Whittington², C. Ashbaugh³, L. M. Remy⁴, D. Aholt⁴, C. Miller⁴, D. Hathaway⁵, D. Clark⁵, K. Goggin⁵, R. J. Ellis⁶, C. L. Russell⁴
¹Surgery/Urology, University of Missouri School of Medicine, Columbia, MO, ²University of Kansas Medical Center, Kansas City, KS, ³University of Missouri Health Care, Columbia, MO, ⁴University of Missouri-Kansas City, Kansas City, MO, ⁵Children's Mercy Kansas City, Kansas City, MO, ⁶Indiana University School of Nursing, Indianapolis, IN
*Purpose: The objective of this evaluation was to estimate the cost of implementation and the cost-effectiveness of a person-level intervention called SystemCHANGETM .*Methods: To estimate…
2021 American Transplant Congress
Selective Bcl-2 Inhibition to Deplete Hematopoietic Stem Cells in Bone Marrow Niche: A Novel Approach to Promote Mixed Chimerism
T. Hirose¹, H. Sasaki¹, G. Lassiter¹, D. Ma¹, T. Oura¹, A. Dehnadi¹, A. Cosimi¹, P. Cippa², T. Fehr², T. Kawai¹
¹Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, ²Institute of Physiology, University of Zurich, Zurich, Switzerland
*Purpose: A recent murine study has shown that successful mixed chimerism is achievable without myelosuppressive treatments by Bcl-2 inhibition. However, the mechanism by which selective…
2021 American Transplant Congress
Brain Natriuretic Peptide and Pedometer Activity are Most Predictive of Poor Kidney Transplant Waitlist Outcomes
P. Manay¹, P. TenEyck², R. Kalil³, M. Sanders⁴, M. Swee⁴, G. Binns⁵, J. Hornikel⁵, D. Katz¹
¹Department of Surgery, University of Iowa, Iowa City, IA, ²Institute for Clinical and Translational Science, University of Iowa, Iowa City, IA, ³Department of Medicine, University of Maryland Medical Center, Baltimore, MD, ⁴Department of Medicine, University of Iowa, Iowa City, IA, ⁵Iowa City VAMC, Iowa City, IA
*Purpose: Tools for indicating which patients are most at risk for complications and death after transplant listing would allow for a rational approach to targeted…
2021 American Transplant Congress
Donor Derived Cell-free-dna (dd-cfdna) as a Surrogate Marker for Kidney Biopsy- Indiana University Transplant Nephrology Experience
S. Valavoor¹, A. Sharfuddin², G. William³, M. Yaqub¹, D. Mishler¹, O. Adebiyi²
¹Nephrology, Indiana University, Indianapolis, IN, ²Transplant Nephrology, Indiana University, Indianapolis, IN, ³Transplant Surgery, Indiana University, Indianapolis, IN
*Purpose: Patient monitoring after kidney transplantation (KT) for early detection of allograft rejection remains key in preventing allograft loss. Donor-derived cell-free DNA (dd-cfDNA), a noninvasive…
2021 American Transplant Congress
Impact of Valganciclovir Prophylaxis Dosing in High Risk Cytomegalovirus Kidney and Pancreas Transplant Recipients with Delayed Graft Function
A. Gharabagi¹, J. Geyston¹, A. Agarwal², S. Rao³, A. Doyle³, J. Dann¹
¹Pharmacy, University of Virginia Health System, Charlottesville, VA, ²Transplant Surgery, University of Virginia Health System, Charlottesville, VA, ³Transplant Nephrology, University of Virginia Health System, Charlottesville, VA
*Purpose: We sought to compare outcomes of cytomegalovirus (CMV) prophylaxis in high risk CMV (donor +/recipient -) kidney and pancreas transplant recipients who received different…