2022 American Transplant Congress
Post-Xenotransplant Antibody Specificities Against Swine, Monkey and Human Leukocyte Antigens in Highly Sensitized Nonhuman Primate Model
Surgery, Duke Transplant Center, Durham, NC
*Purpose: Xenotransplantation has been proposed as a bridge to transplant for allosensitized patients. However, the potential of xenotransplantation to broaden HLA allosensitization due to MHC…2022 American Transplant Congress
Preliminary Data of the Safety and Immunogenicity Protocol of Vaccination for SARS-CoV 2 in Solid Organ Transplant Patients in Argentina
*Purpose: To evaluate the safety and generation rate of Ab anti spike rate in SOT patients at 28 and 90 days after completing the Covid…2022 American Transplant Congress
Kidney Transplant Recipients Not Reaching the Expected Post-Transplant Creatinine Range Most Likely Show Calcineurin-Inhibitor Nephrotoxicity Upon Histology
1University Hospital Zürich, Zürich, Switzerland, 2University Hospital Zurich, Zürich, Switzerland
*Purpose: Very recently, our own data suggested that approximately 25% of deceased-donor kidney transplant recipients (KTRs) and 10% of living-donor KTRs don’t reach the expected…2022 American Transplant Congress
Use of De Novo mTOR Inhibitors in Highly Sensitized Kidney Transplant Recipients
*Purpose: mTOR inhibitors (mTORi) allow calcineurin-inhibitor reduction without loss of efficacy and may improve allograft-transplant outcomes. However, the safety of this protocol in high-immunological risk…2022 American Transplant Congress
No Difference in Graft Survival Among Low Socioeconomic Kidney Allograft Recipients
*Purpose: Low socioeconomic status remains a barrier in access and equity in kidney transplantation with limited data assessing post-transplant outcomes. Alternative options to transplantation include…2022 American Transplant Congress
A Novel Mismatch That Modulates the Innate Alloresponse Risk Stratifies Renal Transplant Patients
Thomas E. Starzl Transplantation Institute, UPMC, Pittsburgh, PA
*Purpose: Donor polymorphism in the gene encoding signal regulatory protein alpha (SIRPα) is a key modulator of the recipient’s innate alloresponse. Here, we investigated the…2021 American Transplant Congress
SARS-CoV-2 Antibody Response After Induction Therapy in Kidney Transplant Recipients
*Purpose: SARS-CoV-2 antibody prevalence in kidney transplant recipients is beginning to be reported, although little is known about the humoral immune response in the immediate…2021 American Transplant Congress
Characterizing the Early Impact of the Kidney Accelerated Placement Project on Hard-to-place Kidneys
Johns Hopkins University, Baltimore, MD
*Purpose: In 2019, the OPTN implemented the Kidney Accelerated Placement Project (KAPP) in an effort to increase the utilization of kidneys with a high Kidney…2021 American Transplant Congress
How Long is the Wait Worthwhile: Cost-Effectiveness of Accepting a Kidney from a Donor with Apolipoprotein L1 High-Risk Genotype
*Purpose: The Apolipoprotein L1 (APOL1) Long-Term Outcomes (APOLLO) study is underway to define the impact of kidney donor renal risk variants (RRVs) on the survival…2021 American Transplant Congress
The Effect of Delayed Graft Function on Early versus Late Mortality Following Kidney Transplantation
*Purpose: Delayed graft function (DGF) is associated with increased risk of long-term graft survival but it’s impact on patient survival has not been studied. Using…
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