Articles tagged "Kidney transplantation"

2022 American Transplant Congress
Viral-Specific Cytotoxic T-Cell Responses in Hla-Sensitized Kidney Transplant Patients Maintained on Everolimus and Low Dose Tacrolimus
R. Zhang¹, S. Ge¹, M. Chu¹, J. Kahwaji², A. Karasyov¹, D. Lovato¹, A. Vo², J. Choi², M. Toyoda¹, S. Jordan²
¹Transplant Immunology Laboratory, Cedars Sinai Medical Center, Los Angeles, CA, ²Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, CA
*Purpose: Post-transplant immunosuppression with “everolimus + reduced dose tacrolimus” (Ev + Taclow) is reported to reduce the risk of viral infections compared to standard doses…
2022 American Transplant Congress
Center Volume and Transplant Outcomes in Adult Kidney Transplant Recipients; A Competing Risk Analysis
A. Azhar¹, E. Defor¹, L. Kamal¹, D. Bandyopadhyay¹, B. Tanriover², G. Gupta¹
¹Virginia Commonwealth University, Richmond, VA, ²University of Arizona, Tuscon, AZ
*Purpose: The precise effect of center volume is a much-debated topic in the field of transplantation. Several studies have shown better post-transplant outcomes in higher…
2022 American Transplant Congress
Predictors of Short and Long Term Outcomes of Donor After Cardiac Death (DCD) versus Donor After Brain Death (DBD) Kidney Transplantation from Supra Marginal Donors ( D4). A Machine Learning Analysis (MLA) of NHSBT Registry Data Since Year 2000
H. Sharma¹, A. Sharma², T. Gunawardhane¹, B. Devkaran¹, K. Kapoor¹, S. Mehra¹
¹Royal Liverpool University Hospital, Liverpool, United Kingdom, ²Loyola University Chicago, Chicago, IL
*Purpose: Marginal Donor 4- D4 ( Donor Risk Index ≥1.50 ) Matching was introduced as a part of new Kidney allocation scheme in the UK…
2022 American Transplant Congress
Direct Health Care Costs Before and After Kidney Transplantation in Germany – A Longitudinal Analysis Based on Claims Data
S. Ronicke¹, K. Budde¹, D. Schmidt², W. Düttmann¹, M. G. Naik¹, C. J. Wagner³, J. Freitag³, B. Osmanodja¹
¹Department of Nephrology and Medical Intensive Care, Charité - Universitätsmedizin Berlin, Berlin, Germany, ²Buisiness Unit IT, Charité - Universitätsmedizin Berlin, Berlin, Germany, ³AOK Nordost Statutory Health Insurance Fund, Berlin, Germany
*Purpose: Kidney transplantation can improve long-term survival and quality of life in transplant candidates with end-stage renal disease and has shown to have long-term economic…
2022 American Transplant Congress
Reduced Dose Mycophenolate Does Not Increase the Risk of Rejection Following Renal Transplantation
L. Bowman¹, A. Webb¹, S. Desai², D. Patino³, V. Subramanian⁴, S. Mohammed⁵, M. Gosselin⁶, K. Robichaux⁵, J. Buggs⁴, A. Kumar⁷
¹Transplant Pharmacy, Tampa General Hospital, Tampa, FL, ²Western University of Osteopathic Medicine, Pomoma, CA, ³Michigan State University College of Human Medicine, Lansing, MI, ⁴Transplant Surgery, Tampa General Hospital, Tampa, FL, ⁵University of South Florida, Tampa, FL, ⁶University of Tampa, Tampa, FL, ⁷Morsani College of Medicine, University of South Florida, Tampa, FL
*Purpose: Mycophenolic acid (MPA) exposure correlates inversely with the risk of acute rejection; however, evidence also suggests that systemic MPA exposure also determines the extent…
2022 American Transplant Congress
Antibody Response and Molecular Graft Surveillance in Kidney Transplant Recipients Following Sars-CoV-2 Vaccination
N. M. Ali¹, J. Miles², S. Mehta¹, V. Tatapudi¹, Z. Stewart¹, B. Lonze¹, M. Mangiola¹, C. DiMaggio¹, E. Weldon¹, I. Saeed¹, J. Leonard¹, R. Herati¹, J. Thomas¹, J. Michael¹, C. Hickson¹, K. Cartiera¹, R. Montgomery¹
¹Transplant Institute, NYU Langone Health, New York, NY, ²CareDx, Brisbane, NY
*Purpose: Preliminary studies suggest that kidney transplant recipients (KTRs) show diminished humoral responses to SARS-CoV-2 vaccination. Although reports of allograft rejection after SARS-CoV-2 vaccination have…
2021 American Transplant Congress
Impact of CHA2DS2-VASc Score on Postoperative Mortality Following Kidney Transplant
J. Klein¹, M. Rangel¹, Z. Spigel², E. Hollinger¹, D. Olaitan¹, M. Hertl¹, E. Chan¹
¹Surgery, Rush University Medical Center, Chicago, IL, ²Surgery, Allegheny Health Network, Pittsburgh, PA
*Purpose: This study aimed to assess the correlation between CHA2DS2-VASc score and postoperative kidney transplant survival. The conditions captured in the CHA2DS2-VASc score are commonly…
2021 American Transplant Congress
Utility of Screening-Bead Assay in Post-Transplant Testing of Donor-Specific Antibodies (DSA) and Antibody-mediated Rejection (ABMR) in Renal Allografts
A. Agrawal¹, E. Dijke², A. Murray³, P. Campbell³
¹Transplant Nephrology, Mayo Clinic, Rochester, MN, ²Lab. Medicine and Pathology, University of Alberta Hospital, Edmonton, AB, Canada, ³Division of Nephrology, Dept. of Medicine, University of Alberta Hospital, Edmonton, AB, Canada
*Purpose: ABMR is a major cause of poor long-term graft survival. Though post-transplant monitoring of HLA DSAs can aid in risk stratification and optimizing immunosuppression,…
2021 American Transplant Congress
Outcomes from High KDPI Kidneys Utilized for Dual Kidney Transplantation
J. Wagler¹, K. Mitchell², S. Ohara³, R. Heilman², S. K. Reddy², H. Khamash², C. Jadlowiec²
¹Mayo Clinic Arizona, Phoenix, AZ, ²Mayo Clinic, Phoenix, AZ, ³Valleywise Health General Surgery Residency Program, Phoenix, AZ
*Purpose: In light of the ongoing organ shortage, dual kidney transplantation (DKT), utilizing two adult kidneys from the same donor for one recipient, has been…
2021 American Transplant Congress
Kidney Paired Exchange in Children in the United-states
J. Hogan¹, A. G. Thomas², J. Verbesey³, D. L. Segev⁴
¹Transplant Research Center, Department of Surgery, Emory University, Atlanta, GA, ²Department of Epidemiology, University of North Carolina, Chapel Hill, NC, ³Department of Surgery, Medstar Georgetown Transplant Institute, Washington, DC, ⁴Department of Surgery, Johns Hopkins University, Baltimore, MD
*Purpose: Kidney paired exchange (KPE) plays an increasing role in the landscape of adult living donor transplant (LDTx) in the US. LDTx is the treatment…