ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2022 American Transplant Congress

    Prolonged Xeno-Kidney Graft Survival in Highly Allo-Sensitized Nonhuman Primate Using Triple-Knockout Donor Pigs with 7 Human Transgenes

    M. Manook1, D. Olaso1, I. Anwar1, J. Yoon1, M. Song1, A. B. Farris2, K. Stiede3, K. Hall3, M. Youd3, S. Knechtle1, J. Kwun1

    1Surgery, Duke Transplant Center, Durham, NC, 2Pathology, Emory University, Atlanta, GA, 3eGenesis Inc, Cambridge, MA

    *Purpose: We have previously shown using porcine kidneys from genetically modified knockout alpha 1,3-galactosyltransferase (GGTA1KO) and human decay accelerating factor transgenic (CD55Tg) pigs that compared…
  • 2022 American Transplant Congress

    Recipient MCPggaac Haplotype is Associated with Poor Graft Survival in Recipients with De Novo Thrombotic Microangiopathy

    V. Petr1, D. Csuka2, P. Hruba3, Á. Szilágyi2, Z. Prohászka2, O. Viklicky1

    1Dept. of Nephrology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, 2Dept. of Medicine and Hematology, Semmelweis University, Budapest, Hungary, 3Transplant Laboratory, Institute for Clinical and Experimental Medicine, Prague, Czech Republic

    *Purpose: De novo thrombotic microangiopathy (TMA) is associated with poor kidney graft survival. We aimed to assess the role of common complement haplotypes in kidney…
  • 2022 American Transplant Congress

    Successful Transplantation of CPRA 95-100% HLA Incompatible (HLA I) KPD Candidates: A New Combined KPD Matching Strategy at a Single Centre

    H. Helwani1, D. Broering2, I. Alahmadi3, T. Ali1, F. Alzayer4, M. Mankowski5, A. Algharabli1

    1Kidney & Pancreas Health Centre, OTCoE, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia, 2Organ Transplant Centre of Excellence, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia, 3Kidney & Pancreas Transplant Surgery, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia, 4King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia, 5King Abdullah University for Science & Technology, Saudi Arabia, Saudi Arabia

    *Purpose: The six components of the new strategy are Universal flexible assignments of unacceptable antigens (UA); individualized deletion of carefully selected UA; inclusion of compatible…
  • 2022 American Transplant Congress

    Antibody Response to Sars- Cov -2 Mrna Vaccine in Kidney Transplant Recipients

    R. Mohamed Abdul Rahman, M. Alkadi, E. Abuhelaiqa, M. Jarman, A. Nauman, O. Fituri, M. Asim, A. Hamad, H. Tohid, P. Coyle, L. Abu Raddad, H. Al-Malki

    Nephrology, Hamad Medical Corporation, Doha, Qatar

    *Purpose: Kidney transplant recipients are vulnerable to develop severe form of COVID19 Infection. Although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA vaccine has significantly…
  • 2022 American Transplant Congress

    Clinical Characteristics Of Serologic Non-responders To Covid-19 Booster Vaccination In A Cohort Of Solid Organ Transplant Recipients.

    F. N. Zervou1, K. Khalil1, T. Lao1, D. Wood2, S. Jonche1, A. Mattoo1

    1Transplant Institute, NYU Langone Health, New York, NY, 2New York University Langone Health, Brooklyn, NY

    *Purpose: The purpose of this study was to assess the clinical characteristics of serologic non-responders to COVID-19 booster vaccination in a cohort of solid organ…
  • 2022 American Transplant Congress

    Factors Contributing To SARS-CoV-2 Vaccine Hesitancy In Kidney Transplant Candidates

    P. LaBella1, E. Silverman2, S. Mehta3, N. M. Ali4

    1Transplant Infectious Disease, New York University Langone Health, New York, NY, 2Transplant Infectious Disease, New York University Grossman School of Medicine, New York, NY, 3New York University Langone Transplant Institute, New York, NY, 4Transplant Institute, NYU Langone Health, New York, NY

    *Purpose: SARS-CoV-2 infection in kidney transplant recipients is associated with an increased risk of severe disease and mortality relative to other patient populations, with mortality…
  • 2021 American Transplant Congress

    A Single Nucleotide Polymorphism within the FCGR3A 158 F/V Gene is Associated with Decreased Survival of Renal Allografts with Chronic Active Antibody-Mediated Rejection

    N. H. Litjens, A. M. Peeters, J. A. Kal-van Gestel, M. Klepper, M. G. Betjes

    Internal Medicine, Nephrology and Transplantation, Erasmus MC, University Medical Center, Rotterdam, Netherlands

    *Purpose: Long-term allograft survival has shown little improvement over the last decades. An important factor compromising long-term allograft survival in kidney transplantation is chronic active…
  • 2021 American Transplant Congress

    Insulin Secretion and Insulin Resistance Trajectories Over 1 Year After Kidney Transplantation: A Multicenter Prospective Cohort Study

    B. Jun Bae, C. Oh

    Department of Surgery, Ajou University Medical School, Suwon, Korea, Republic of

    *Purpose: We investigated the changing patterns of insulin secretion and resistance and risk factors contributing to the development of post-transplant diabetes mellitus (PTDM) in kidney…
  • 2021 American Transplant Congress

    Profound Opportunities Lost: Patients with High Priority for Ideal Donor Kidneys That are Not Placed on the Kidney Transplant Waiting List

    J. Schold1, A. Huml1, E. Poggio1, J. Sedor1, S. Husain2, K. L. King2, S. Mohan2

    1Cleveland Clinic Foundation, Cleveland, OH, 2Columbia University, New York, NY

    *Purpose: The national Kidney Allocation System(KAS) prioritizes patients with high (top 20%) Estimated Post-Transplant Survival (EPTS) with expedited access to high quality deceased donor kidneys.…
  • 2021 American Transplant Congress

    Pharmacokinetic Analysis of Direct Acting Antiviral Use on Weight-Adjusted FK506 Trough/dose Ratios in Obese Kidney Transplant Recipients

    A. Demirag1, P. L. Lobo2, J. Oberholzer1, A. Kumar2, B. Rawashdeh1, S. L. Lennon1, H. N. Guvener Demirag1, A. Doyle2, J. Geystone3, K. L. Brayman1

    1Transplantation, University of Virginia Medical Center, Charlottesville, VA, 2Transplantation Nephrology, University of Virginia Medical Center, Charlottesville, VA, 3Clinical Pharmacy, University of Virginia Medical Center, Charlottesville, VA

    *Purpose: Using hepatitis C viremic (HCV) organs in kidney transplant recipients(KTRs) is very important to decrease the number of patients on the waiting list. Direct…
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