2022 American Transplant Congress
Reduction of Rabbit Anti-Thymocyte Globulin Dosing for Induction of Kidney Transplant During the COVID-19 Pandemic
*Purpose: Rabbit anti-thymocyte globulin (rATG) is a polyclonal antibody utilized for induction immunosuppression in high immunologic risk kidney transplant recipients. However, the optimal total dose…2022 American Transplant Congress
Impact of Immunosuppressive Medications on SARS-CoV-2 Vaccination Response in Kidney Transplant Patients
*Purpose: The COVID-19 pandemic portends significant morbidity and mortality in immunocompromised individuals. Vaccination against COVID-19 among immunocompromised population is an essential step to minimize deadly…2022 American Transplant Congress
Deep-Learning Based Pathological Assessment of Frozen Procurement Kidney Biopsies
*Purpose: Organ shortage in kidney transplantation is a major issue for ESKD individuals on the waiting list. Sclerotic glomeruli or interstitial fibrosis on procurement donor…2022 American Transplant Congress
Critical Care of the Brain-Dead Recipient of a Pig-to-Human Renal Transplant
1NYU Langone Transplant Institute, New York, NY, 2NYU Langone Health, New York, NY
*Purpose: The care of a brain dead (BD) patient undergoing xenotransplantation in a non-clinical environment poses unique challenges. Selection of an appropriate decedent, stabilization of…2022 American Transplant Congress
Donor Factors Do Not Discriminate Living Donor Kidney Transplant Outcomes and Should Not Be Used to Promote the Use of Compatible Pairs in Kidney Paired Donation Programs
*Purpose: Enrolment of ABO blood group and HLA incompatible pairs in kidney paired donation programs improves matching potential. The benefit for compatible pairs, however, is…2022 American Transplant Congress
Predicting Long Term Kidney-Allograft Failure: Machine Learning vs Traditional Statistical Models
1Paris Transplant Group, Paris, France, 2Hôpital Saint-Louis, Paris, France
*Purpose: Prognostic models have been developed in organ transplant over the past years using traditional statistical models. However, whether these are outperformed by machine learning…2022 American Transplant Congress
Iguratimod Alleviates Endothelial to Mesenchymal Transition by Inducing AMBRA1/PARKIN-Dependent Mitophagy and Inhibiting NLRP3 Activation During Renal Allograft Interstitial Fibrosis
*Purpose: Chronic renal graft dysfunction (CAD) is caused by multiple factors, including glomerular sclerosis, inflammation, interstitial fibrosis and tubular atrophy (IF/TA). However, the most prominent…2022 American Transplant Congress
Delayed Graft Function in Kidney Transplant Recipients is Associated with an Increased Risk f Post-Transplant Infections
*Purpose: Delayed graft function (DGF) is a known complication among kidney transplant recipients (KTRs) and is associated with decreased graft survival, increased rejection, and increased…2022 American Transplant Congress
RBBP7 as a Novel Biomarker for the Molecular Diagnosis of BK Virus-Associated Nephropathy
Department of Urology, Beijing Chaoyang Hospital, Beijing, China
*Purpose: BK virus-associated nephropathy (BKVN) remains a major infectious complication of kidney transplantation, and its histologic appearance can mimic rejection, leading to a diagnostic dilemma…2022 American Transplant Congress
Glomerular Filtration Rates (GFR) Reference Values for Living Kidney Donors Using the 2021 CKD-EPI Equation without the Race Factor
Cleveland Clinic, Cleveland, OH
*Purpose: Kidney function is central to donor evaluation and KDIGO guidelines recommend using estimated GFR (eGFR) for initial screening. A new creatinine-based CKD-EPI equation ('21…
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