2022 American Transplant Congress
Process Evaluation of the Ascent Study: A Hybrid Type 1 Effectiveness-Implementation Trial of a Multi-Level Intervention to Improve Dialysis Provider Knowledge of Kidney Allocation Policy Changes and Increase Kidney Transplant Waitlisting
*Purpose: Kidney transplant is the optimal treatment for end-stage kidney disease, yet only a fifth of patients are on the waitlist and inequities in access…2022 American Transplant Congress
Donor-Derived Cell-Free DNA Trends Before and After Rejection Vary Based on Timing of Rejection
1Northwestern University, Chicago, IL, 2Transplant Nephrology, Northwestern University, Chicago, IL
*Purpose: Donor-derived cell-free DNA (dd-cfDNA) has been used for acute rejection detection and trending levels may help predict future rejection and assess the adequacy of…2022 American Transplant Congress
Impact of Sars-CoV-2 Vaccination on Donor-Derived Cell Free DNA Levels in Renal Transplant Recipients
Columbia University Irving Medical Center, New York, NY
*Purpose: COVID-19 poses a disproportionate threat to renal transplant recipients (RTR), who are chronically immunosuppressed. Studies have indicated a 16% mortality rate compared to2022 American Transplant Congress
Inflammation After Kidney Transplantation Is Associated With Overall- And Death-censored Graft Loss
Department of Transplantational Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway
*Purpose: Early graft loss after kidney transplantation (KT) is mainly a result of acute rejection, while long-term graft loss episodes are often dependent on multifactorial…2022 American Transplant Congress
Pegloticase Use in Renal Transplant Recipients with Gout: Findings from an Insurance Claims Database Study
1Iowa Kidney Physicians, Des Moines, IA, 2Horizon Therapeutics plc, Deerfield, IL
*Purpose: Kidney transplant (KT) recipients have high gout incidence due to reduced eGFR and medication use associated with hyperuricemia.1 Oral urate-lowering therapies in KT patients…2022 American Transplant Congress
The Impact of Maintenance Immunosuppressive Regimen on COVID-19 Outcomes Among Kidney Transplant Patients
*Purpose: Compared to azathioprine (AZA), mycophenolate (MPA) is implicated in an increased risk of several viral infections. Contrariwise, mTOR inhibitors (mTORi) are protective. Therefore, the…2022 American Transplant Congress
Time-Dependent Blood Eosinophilia Count Increases the Risk of Kidney Allograft Rejection
*Purpose: There is growing evidence that type 2 immune effectors (immunoglobulin E, eosinophils, mast cells/basophils) play a role in autoimmune disorders and solid organ transplantation.…2022 American Transplant Congress
Donor Disposition AI Model to Predict Transplant for Recovered Deceased Donor Kidneys
1MST, Rolla, MO, 2SLU, Saint Louis, MO
*Purpose: Current practice for accelerated kidney placements rely heavily on the Kidney Donor Profile Index (KDPI) to determine if recovered deceased-donor (DD) kidneys are hard-to-place.…2022 American Transplant Congress
Outcomes of Kidney Transplant Recipients with Covid-19 in Singapore Treated with Sotrovimab in the Era of the Delta Variant
*Purpose: Kidney transplant recipients (KTRs) are at higher risk for severe COVID-19 caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Sotrovimab decreases the risk…2022 American Transplant Congress
Pump Resistance Thresholds and Graft Outcomes in Machine Perfused Kidneys-A Single Center Retrospective Study
Univ of Miami Miller School of Medicine, Miami, FL
*Purpose: Perfusion parameters are increasingly used to assess the quality of organs and to make decisions about discarding the organ. Resistive index(RI) has been an…
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