2022 American Transplant Congress
Single Cell RNA Sequencing Identifies Primarily Terminal Effector and Exhausted CD8+T Cells in Chronically Rejected Human Kidney Allografts
*Purpose: Chronic renal allograft rejection often leads to irreversible damage, despite intensification of immunosuppression (ISN). T cell phenotypes in this clinical setting are not well…2022 American Transplant Congress
Identification of a Unique and Mechanistic Urinary Cell mRNA Signature in Tolerant Kidney Transplant Recipients Conditioned with FCR001 Facilitating Cells
*Purpose: Urinary cell mRNA profiling is a powerful tool to interrogate kidney allograft status and can diagnose and anticipate acute rejection in kidney allograft recipients.…2022 American Transplant Congress
Incidence of De Novo Donor Specific Antibodies After Early Steroid Withdrawal in Kidney Transplant Recipients
Temple University Hospital, Philadelphia, PA
*Purpose: Early steroid withdrawal (ESW) regimens may lead to the formation of de novo donor-specific antibodies (dnDSA) post-kidney transplant, which increases the risk of antibody-mediated…2022 American Transplant Congress
The Correlation of Dd-cfdna and Donor Specific Antibodies in Kidney Transplant Recipients
Johns Hopkins Hospital, Baltimore, MD
*Purpose: Donor derived cell free DNA (dd-cfDNA) is increasingly being utilized to discern the presence of rejection in kidney transplant recipients (KTRs). There continues to…2022 American Transplant Congress
Older Living Donor Kidneys Are Associated with Worse Recipient and Graft Survival Compared to Younger Donors
1Medicine, University of Minnesota, Minneapolis, MN, 2Analytics, Mhealth-Fairview, Minneapolis, MN
*Purpose: Older living donors (LDs) are accepted more frequently to expand the donor pool. We sought to evaluate recipient outcomes from older LDs >70y.*Methods: Utilizing…2022 American Transplant Congress
APN-Driven COVID-19 Monitoring Model for Kidney Transplant Patients
Loyola University Medical Center, Maywood, IL
*Purpose: COVID-19 infection in kidney transplant (KT) recipients is characterized by an unpredictable course and can be life-threatening. Prompt adjustment of immunosuppression and hospitalization when…2022 American Transplant Congress
Pseudomonas Related Pseudoaneurysm and Rupture of Transplant Renal Artery with Devastating Consequences – A Case Series
*Purpose: Only few cases of infectious pseudoaneurysm of the transplant renal artery caused by Pseudomonas aeruginosa are reported in literature. Here we describe three such…2022 American Transplant Congress
Impact of Kidney Transplant on Post-Operative Morbidity and Mortality in Patients with Pre-Existing Cardiac Conditions (Low Ejection Fraction): A Case Series
Abdominal Transplant Surgery, UNC School of Medicine, Chapel Hill, NC
*Purpose: Patients with underlying cardiac diseases have higher morbidity and mortality as compared to the patients without any cardiac diseases. There has been a number…2022 American Transplant Congress
Kinetic Analysis of Post-Clearance Phase Inflammation in Kidney Biopsies After BK Viremia
1University of Michigan, Ann Arbor, MI, 2Dept. of Pathology, University of Michigan, Ann Arbor, MI
*Purpose: During the post-clearance phase of BK polyomavirus nephropathy, tubulointerstitial inflammation can persist despite resolution of BK viremia. This inflammation is indistinguishable from low grade…2022 American Transplant Congress
Pre-Transplant Ex-Vivo Analysis of Kidney Vasculature and Perfusion Using Contrast Computed Tomography
1Yale School of Medicine, New Haven, CT, 2University of Cambridge, Cambridge, United Kingdom
*Purpose: Ex-vivo normothermic perfusion (NMP) has been developed with the goal of improving viability of the thousands of donated organs that are declined for transplant…
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