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American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2022 American Transplant Congress

    Financial Barriers Experienced During the Transplant Process by Caregivers of Children with End Stage Kidney Disease

    R. Goldfarb Terry1, A. Edwards1, U. Parlin2, A. Chung1, S. Amaral1

    1Division of Nephrology, Children's Hospital of Philadelphia, Philadelphia, PA, 2University of Pittsburgh Medical Center, Pittsburgh, PA

    *Purpose: Known socioeconomic disparities in transplant referral and evaluation exist in adults with end-stage kidney disease, but little is known about the financial burden that…
  • 2022 American Transplant Congress

    Diagnostic Performance of Donor-Derived Cell-Free DNA Assay (AlloSure®) in Kidney Transplant Recipients with Graft Dysfunction: A Single Center Study

    M. S. Naseer1, H. Shokouh-Amiri2, T. Creamer1, R. McMillan2, S. Tandukar1, D. Aultman1, G. B. Zibari1, N. Singh1

    1Transplant, John C. McDonald Regional Transplant Center - Willis Knighton Health System, Shreveport, LA, 2John C. McDonald Regional Transplant Center - Willis Knighton Health System, Shreveport, LA

    *Purpose: Circulating donor-derived cell-free DNA (dd-cf-DNA) is a non-invasive biomarker of kidney allograft injury with a high negative predictive value for ruling out active rejection…
  • 2022 American Transplant Congress

    Faster B Cell Rebound is Observed Following Xenotransplantation Compared to Allotransplantation in a Highly Sensitized Nonhuman Primate Kidney Transplantation Model

    I. DeLaura, M. Manook, D. Olaso, J. Yoon, R. Baldi, S. Knechtle, J. Kwun

    Surgery, Duke Transplant Center, Durham, NC

    *Purpose: Xenotransplantation outcomes have been greatly improved due to the advent of genetically engineered pigs and agents targeting the CD40-CD40L signaling pathway. However, studies have…
  • 2022 American Transplant Congress

    Validation of Trugraf Gene Expression Profile in a Multicenter Cohort (TOGETHER Study)

    M. Mai1, W. Park2, R. Heilman3, B. Smith2, R. First4, J. Fleming4, P. West-Thielke4, J. Holman4, M. Stegall2

    1Mayo Clinic Jacksonville, Jacksonville, FL, 2Mayo, Rochester, MN, 3Mayo, Phoenix, AZ, 4Transplant Genomics, Framingham, MA

    *Purpose: The purpose of this study was to validate the performance characteristics of TruGraf GEP in a real-world population.*Methods: This was a multicenter observational analysis…
  • 2022 American Transplant Congress

    Impact of Early Calcineurin-Inhibitor Conversion to Belatacept on Renal Allograft Function in a Steroid-Free Maintenance Regimen: Results from a Randomized Controlled Study

    I. Tawhari1, P. Hallak1, S. Hartzell2, V. Mas3, P. Cravedi2, J. Leventhal1, J. Ansari1, L. Gallon1

    1Northwestern University, Chicago, IL, 2Mount Sinai, New York, NY, 3University of Maryland, Baltimore, MD

    *Purpose: Belatacept (Bela) was developed to minimize nephrotoxicity and cardiovascular risk associated with Calcineurin inhibitors (CNIs). Early steroid withdrawal (ESW) and simultaneous CNI avoidance (CNIA)…
  • 2022 American Transplant Congress

    Impact of End-of-Chain Kidney Allocation on Access to Kidney Transplantation of Minority Patients: Implications for Reducing Disparities

    J. Wade1, K. Rancourt2, A. Anane2, A. Landeen2, J. U. Singh3, X. Ye3, J. Tremaglio3, Z. Ebcioglu3, R. Kent3, B. Emmanuel4, G. Morgan4, O. K. Serrano4, W. Dar4

    1Department of Surgery, Surgical Research Program, Hartford Hospital, Hartford, CT, 2Hartford Hospital Transplant & Comprehensive Liver Center, Hartford, CT, 3Department of Medicine, Hartford Hospital Transplant & Comprehensive Liver Center, Hartford, CT, 4Department of Surgery, Hartford Hospital Transplant & Comprehensive Liver Center, Hartford, CT

    *Purpose: Disparities in access to kidney transplantation (KT) among non-White patients is well-known, especially as it relates to living donor kidney transplantation (LDKT). We investigated…
  • 2022 American Transplant Congress

    Trends in Donor Derived Cell Free DNA Before and After Cellular and Antibody Mediated Rejection

    K. Guo1, J. Friedewald1, C. Rebello1, B. Kinsella1, S. Park2, L. Zhao1

    1Northwestern University, Chicago, IL, 2Transplant nephrology, Northwestern University, Chicago, IL

    *Purpose: The TRAC dd-cfDNA test was developed to detect acute kidney transplant rejection but can also detect subclinical rejection with improved performance in antibody-mediated rejection…
  • 2022 American Transplant Congress

    A Three-gene Peripheral Blood Potential Diagnosis Signature Associated With Autophagy For Antibody-mediated Rejection In Renal Transplantation

    Y. Wang, Y. Xu, H. Zhang, X. Hu

    Department of Urology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China

    *Purpose: Antibody-mediated rejection (AMR) is emerging as a major cause of graft loss in renal transplantation. Nowadays, non-invasive diagnosis of AMR with high accuracy is…
  • 2022 American Transplant Congress

    Lucas Device Assisted Uncontrolled Dcd Kidney Transplantation – A Feasible but Underutilized Option in the United States

    S. Nagaraju, S. Vaishnav, R. Savilla, M. Moore, J. B. Africa

    Renal Transplant, Charleston Area Medical Center, Charleston, WV

    *Purpose: Uncontrolled DCD (uDCD) procurement involves either normo-thermic or hypothermic regional perfusion to reduce ischemic injury. We report a series of successful kidney transplant utilizing…
  • 2022 American Transplant Congress

    Single Kidney Transplantation from Small Pediatric Donors Aged < 2 Years Into Pediatric Recipients: A Retrospective Single-Center Cohort Study

    Q. Zhang, M. Huang, J. Li, W. Wu, H. Zhang, C. Wu, Q. Fu, P. Gao, L. Ling, W. Chen, B. Xu, X. Su, L. Liu, C. Wang

    Organ Transplant Center, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China

    *Purpose: Kidneys from small pediatric donors (aged < 2 years, SPD) are underutilized. Concerns regarding potentially inferior outcomes hinder the use in pediatric recipients, especially…
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