ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2022 American Transplant Congress

    Conversion to Everolimus-Based Immunosuppression Regimen with Calcineurin Inhibitor Reduction Ameliorates Histological Damage in Kidney Transplant Recipients with Calcineurin Inhibitor-Induced Nephrotoxicity

    K. Hotta, N. Iwahara, T. Tanabe, N. Shinohara

    Hokkaido University Hospital, Sapporo, Japan

    *Purpose: In the last two decades, the short-term results for kidney transplantation (KTX) have improved owing to the use of calcineurin inhibitors (CNIs). However, long-term…
  • 2022 American Transplant Congress

    Cold Pulsatile Perfusion Preservation of Deceased Donor Kidneys Did Not Improve Delayed Graft Function Rates in Most Transplants Due to Longer Cold Ischemia Times Offsetting Much of the Benefit, Analysis of SRTR Database

    D. S. Keith, E. Lessmann

    Kidney Transplant, Ascension Sacred Heart Hospital, Pensacola, FL

    *Purpose: To determine the impact of cold pulsatile perfusion preservation (CPPP) on delayed graft function (DGF) in a national cohort of US kidney transplants as…
  • 2022 American Transplant Congress

    Prediction of Delayed Graft Function After Deceased Donor Kidney Transplantation Using Machine Learning and Sequential Donor Data

    J. Sageshima1, J. Yu1, H. Lala Gul1, F. De Leon1, N. Goussous1, N. Mineyev1, P. Than1, K. Jen2, R. Perez1

    1Surgery, University of California Davis Health, Sacramento, CA, 2Pathology, University of California Davis Health, Sacramento, CA

    *Purpose: Delayed graft function (DGF) has been associated with adverse kidney transplant outcomes. Accurate prediction of DGF before surgery will help select organs and candidates…
  • 2022 American Transplant Congress

    Deep Learning Identifies Arterial Intimal Fibrosis in Kidney Transplant Biopsies

    K. Liu1, Z. Yi2, S. Ward3, F. Salem3, W. Zhang2

    1Nephrology, Icahn School of Medicine at Mount Sinai, New York, NY, 2Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 3Molecular and Cell Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY

    *Purpose: Arterial intimal fibrosis (AIF) is the excessive fibrotic tissue formation in the intima of arteries indicative of poor graft function after kidney transplant. Visual…
  • 2022 American Transplant Congress

    DCD and AKI Kidneys Experiencing DGF as a Platform for the Study of Adaptive Repair

    B. Bussolati1, S. Da Sacco2, A. Asthana3, L. N. Byers3, L. Perin4, M. S. Garner3, B. Sharda3, A. C. Farney3, C. J. Jay3, R. J. Stratta3, S. J. Walker5, G. Orlando3

    1University of Turin, Turin, Italy, 2Children Hospital Los Angeles, Los Angeles, NC, 3Wake Forest Baptist Medical Center, Winston-Salem, NC, 4Children Hospital Los Angeles, Los Angeles, CA, 5WFIRM, Winston-Salem, NC

    *Purpose: AKI and DCD renal allografts are at high risk for DGF, yet the majority of these kidneys will eventually recover and attain good function…
  • 2022 American Transplant Congress

    Interaction Between Financial Barriers and Other Motivators, Barriers, and Facilitators of Living Organ Donation

    A. R. Smith1, R. J. Mandell1, M. E. Helmuth1, N. P. Goodrich1, J. B. Wiseman1, K. A. Gifford2, M. A. Fava1, A. O. Ojo3, R. M. Merion1, A. K. Mathur4

    1Arbor Research Collaborative for Health, Ann Arbor, MI, 2American Society for Transplant Surgeons, Arlington, VA, 3University of Kansas Medical Center, Kansas City, KS, 4Mayo Clinic, Phoenix, AZ

    *Purpose: Our objective was to assess how financial barriers to living donation interact with other motivators, barriers, and facilitators during the decision-making process.*Methods: Data were…
  • 2022 American Transplant Congress

    Comparative Analysis of kSORT Assay for Predicting Acute Renal Allograft Rejection Under Belatacept-Based Immunosuppression

    H. Hames1, M. Sarwal2, I. Damm2, E. Yanqui1, A. Burg1, A. Christianson1, A. R. Shields1, D. Hildeman1, R. R. Alloway1, E. S. Woodle1

    1University of Cincinnati, Cincinnati, OH, 2University of California San Francisco, San Francisco, CA

    *Purpose: The kSORT (Kidney Solid Organ Response Test) assay uses transcriptomic profiling of peripheral blood to predict the presence of acute rejection (AR) in renal…
  • 2022 American Transplant Congress

    Association Between De Novo Donor Specific Antibody and Tacrolimus Trough Levels in Long Term Follow Up Renal Transplantation

    N. Fujiyama1, M. Saito2, R. Yamamoto2, R. Sagehashi2, T. Saito2, Y. Aoyama2, K. Numakura2, T. Habuchi2, S. Satoh1

    1Center for Kidney Disease and Transplantation, Akita University Hospital, Akita, Japan, 2Department of Urology, Akita University Graduate School of Medicine, Akita, Japan

    *Purpose: In this study, we aimed to identify the risk factors contributing to the development of donor-specific anti-HLA antibody (DSA) during long-term follow-up of patients…
  • 2022 American Transplant Congress

    Variability of Serum Klotho and FGF-23 Levels During the First Two Years After Kidney Transplantation

    T. Vazquez-Sanchez1, M. Sanchez-Niño2, P. Ruiz-Esteban1, V. López1, J. Delgado1, A. Ortiz3, D. Hernández1

    1Nephrology Department, Regional University Hospital (IBIMA), REDinREN (RD16/0009/0006), Malaga (España), Malaga, Spain, 2Nephrology Department, Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz, Universidad Autónoma de Madrid. REDINREN, Madrid, Spain, 3Nephrology Department, Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz, Universidad Autónoma de Madrid. REDINREN, Madrid, Spain, Madrid, Spain

    *Purpose: Klotho is a protein produced in renal tubular cells with nephroprotective actions which acts as a co-receptor for phosphaturic factor FGF-23. The natural history…
  • 2022 American Transplant Congress

    A Randomised Trial Of Normothermic Machine Perfusion Versus Static Cold Storage In Donation After Circulatory Death Renal Transplantation

    S. Hosgood1, C. Callaghan2, C. Wilson3, G. Oniscu4, B. Phillips5, L. Bates3, L. Smith6, M. L. Nicholson7

    1Surgery, University of Cambridge, Cambridge, United Kingdom, 2Transplant, Guys & St Thomas's, London, United Kingdom, 3Transplant, Freeman Hospital, Newcastle, United Kingdom, 4Edinburgh Royal Infirmary, Edinburgh, United Kingdom, 5Transplant, Guy's & St Thomas's, London, United Kingdom, 6NHSBT, NHSBT, Bristol, United Kingdom, 7University of Cambridge, Cambridge, United Kingdom

    *Purpose: Kidneys from donation after circulatory death (DCD) donors are more susceptible to cold storage injury and have a high risk of delayed graft function…
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