2022 American Transplant Congress
Tolerance of Allogeneic Kidneys with Durable (>200 Days) Multilineage Chimerism and Bone Marrow Engraftment in Cynomolgus Macaques
*Purpose: We have previously reported that a regimen including anti-CD3 immunotoxin, 45 days of cyclosporine, and pre-transplant total body irradiation (TBI) promoted tolerance of kidney…2022 American Transplant Congress
Daratumumab for Recurrence of Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposits in a Post-Kidney Transplant Recipient: A Case Report
*Purpose: Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposits (PGNMID) is a rare kidney disease associated with a high rate of recurrence post-kidney transplantation resulting in graft…2022 American Transplant Congress
Pretransplant Transcriptome Predicts 24-Month Kidney Function
*Purpose: With the development of novel prognostic tools derived from omics technologies, transplant medicine is entering the era of precision medicine, however, there are no…2022 American Transplant Congress
Increased Costs, Cold Ischemia Time, and Sharing Associated with Removing DSA and OPTN Region from Kidney Allocation: A Single-Center Analysis
*Purpose: On March 15, 2021, Donation Service Area (DSA) and OPTN Region were removed from kidney allocation and replaced with a 250 nautical mile (NM)…2022 American Transplant Congress
Predictors Associated with Survival Outcomes for DCD and DBD Renal Transplants from D4 Donors. A Registry Based Machine Learning Analysis (MLA)
*Purpose: Marginal Donor 4- D4 ( Donor Risk Index ≥1.50 ) Matching was introduced as a part of new Kidney allocation scheme in the UK…2022 American Transplant Congress
Final Flow and Resistance with Cold Pulsatile Perfusion Preservation Are Independent Risk Factors for Dialysis in the First Week Post-Transplant, Analysis of SRTR Data
Kidney Transplant, Ascension Sacred Heart Hospital, Pensacola, FL
*Purpose: To determine if final flow or resistance on cold pulsatile perfusion preservation (CPPP) have independent predictive value for dialysis in the first week post-transplant.*Methods:…2022 American Transplant Congress
Testing an Education Only Intervention to Increase Willingness and Pursuit of Living Donor Kidney Transplantation
*Purpose: The Talking About Live Kidney Donation (TALK) intervention uses an educational video and booklet to improve consideration and pursuit of LDKT in kidney failure…2022 American Transplant Congress
Blood Transcriptomes of Covid-19 Infected Kidney Recipients Demonstrate Frequent and Persistent Sars-cov-2 Virome Gene Expression
*Purpose: Kidney transplant recipients (KTRs) have poor outcomes vs non-KTRs with acute COVID-19. To provide insight into management of immunosuppression during acute COVID-19, we studied…2022 American Transplant Congress
Alloreactive Regulatory T Cells Release Distinct Subpopulations of Extracellular Vesicles Bearing Immune Regulatory Proteins and the TCR/CD3 Complex Under Antigen Specific Stimulation
Brigham and Women's Hospital, Boston, MA
*Purpose: Extracellular vesicles (EVs) are vital mediators of intercellular communication, playing an important role in the immune synapse and the T cell response. However, regulatory…2022 American Transplant Congress
Use of Dd-cfdna to Guide Tapering of Immunosuppression Therapy in Kidney Transplant Recipients
1Victoria Kidney and Dialysis Associates, Victoria, TX, 2Natera, Inc., Austin, TX
*Purpose: Continuous administration of immunosuppressive therapy (IST) is required to avoid allograft rejection in transplant recipients. However, these therapeutic interventions can lead to significant side…
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