2022 American Transplant Congress
Faster B Cell Rebound is Observed Following Xenotransplantation Compared to Allotransplantation in a Highly Sensitized Nonhuman Primate Kidney Transplantation Model
Surgery, Duke Transplant Center, Durham, NC
*Purpose: Xenotransplantation outcomes have been greatly improved due to the advent of genetically engineered pigs and agents targeting the CD40-CD40L signaling pathway. However, studies have…2022 American Transplant Congress
Validation of Trugraf Gene Expression Profile in a Multicenter Cohort (TOGETHER Study)
*Purpose: The purpose of this study was to validate the performance characteristics of TruGraf GEP in a real-world population.*Methods: This was a multicenter observational analysis…2022 American Transplant Congress
Impact of Early Calcineurin-Inhibitor Conversion to Belatacept on Renal Allograft Function in a Steroid-Free Maintenance Regimen: Results from a Randomized Controlled Study
*Purpose: Belatacept (Bela) was developed to minimize nephrotoxicity and cardiovascular risk associated with Calcineurin inhibitors (CNIs). Early steroid withdrawal (ESW) and simultaneous CNI avoidance (CNIA)…2022 American Transplant Congress
Impact of End-of-Chain Kidney Allocation on Access to Kidney Transplantation of Minority Patients: Implications for Reducing Disparities
*Purpose: Disparities in access to kidney transplantation (KT) among non-White patients is well-known, especially as it relates to living donor kidney transplantation (LDKT). We investigated…2022 American Transplant Congress
Trends in Donor Derived Cell Free DNA Before and After Cellular and Antibody Mediated Rejection
1Northwestern University, Chicago, IL, 2Transplant nephrology, Northwestern University, Chicago, IL
*Purpose: The TRAC dd-cfDNA test was developed to detect acute kidney transplant rejection but can also detect subclinical rejection with improved performance in antibody-mediated rejection…2022 American Transplant Congress
A Three-gene Peripheral Blood Potential Diagnosis Signature Associated With Autophagy For Antibody-mediated Rejection In Renal Transplantation
Department of Urology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
*Purpose: Antibody-mediated rejection (AMR) is emerging as a major cause of graft loss in renal transplantation. Nowadays, non-invasive diagnosis of AMR with high accuracy is…2022 American Transplant Congress
Lucas Device Assisted Uncontrolled Dcd Kidney Transplantation – A Feasible but Underutilized Option in the United States
Renal Transplant, Charleston Area Medical Center, Charleston, WV
*Purpose: Uncontrolled DCD (uDCD) procurement involves either normo-thermic or hypothermic regional perfusion to reduce ischemic injury. We report a series of successful kidney transplant utilizing…2022 American Transplant Congress
Single Kidney Transplantation from Small Pediatric Donors Aged < 2 Years Into Pediatric Recipients: A Retrospective Single-Center Cohort Study
Organ Transplant Center, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China
*Purpose: Kidneys from small pediatric donors (aged < 2 years, SPD) are underutilized. Concerns regarding potentially inferior outcomes hinder the use in pediatric recipients, especially…2022 American Transplant Congress
Long-Term Clinical Outcomes in ABO Incompatible Kidney Transplantation in Patients with High Baseline Anti-A/B Antibody Titer
*Purpose: ABO incompatible (ABOi) kidney transplantation (KT) has been considered to overcome donor shortage. We investigated the long-term clinical outcomes in ABOi KT in patients…2022 American Transplant Congress
Novel Biopsy-Based Clinical Phenotype Clustering to Predict Kidney Transplant Outcomes
*Purpose: The purpose of this study was to define novel clinical phenotypes based on biopsy results to enhance biomarker discovery.*Methods: Retrospective analysis of kidney biopsy…
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