ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2022 American Transplant Congress

    Local Cognate Antigen in Kidney Allografts Promotes Tissue Resident Memory T Cell Maintenance

    R. Tieu1, Q. Zeng1, D. Zhao1, P. Manandhar2, A. Williams1, K. Abou-Daya1, L. Kane2, W. Shlomchik1, M. Oberbarnscheidt1, F. Lakkis1

    1Starzl Transplantation Institute, Pittsburgh, PA, 2Department of Immunology, University of Pittsburgh, Pittsburgh, PA

    *Purpose: Our lab has demonstrated that tissue resident memory T cells (TRM cells) sustain chronic kidney allograft rejection in mice. It remains unknown how TRM…
  • 2022 American Transplant Congress

    No Grapefruit Juice Interaction with Tacrolimus LCP in Kidney Transplant Recipients

    J. Kerr1, Y. Sepulveda2, M. Shah3, A. Khan4, J. D. Momper2, S. Tsunoda2

    1Center for Transplantation, UC San Diego Health, San Diego, CA, 2UCSD Skaggs School of Pharmacy and Pharmaceutical Sciences, San Diego, CA, 3Nephrology, UC San Diego Health, San Diego, CA, 4UCSD Center for Transplantation, San Diego, CA

    *Purpose: It is well known that grapefruit juice (GFJ) interacts with many medications through an intestinal CYP3A-mediated interaction that does not involve hepatic CYP3A and…
  • 2022 American Transplant Congress

    Enhanced Histological Yield and Actionable Findings When Biopsy is Guided by Donor-Derived Cell-Free DNA (dd-cfDNA)

    M. R. Weir1, D. Mandelbrot2, J. S. Bromberg1, S. Mehta3, E. Poggio4, E. Huang5, G. Shekhtman6, N. Agrawal7, W. Tian8, M. Cooper9

    1University of Maryland School of Medicine, Baltimore, MD, 2University of Wisconsin, Madison, WI, 3University of Alabama, Birmingham, AL, 4Cleveland Clinic, Cleveland, OH, 5Cedars-Sinai Medical Center, Los Angeles, CA, 6CareDx Inc., Brisbane, CA, 7CareDx Inc, Brisbane, CA, 8CareDx, Brisbane, CA, 9MedStar Georgetown Transplant Institute, Washington, DC

    *Purpose: Implementation of molecular biomarkers in kidney transplantation has expanded the amount of information available to clinicians before deciding to pursue biopsy. We evaluated how…
  • 2022 American Transplant Congress

    A Pilot Study Using Registry-Based External Controls for the Cyclosporine Arm of the BENEFIT Study

    A. Klein1, D. Stewart2, A. Toll2, W. E. Fitzsimmons1

    1Transplant Therapeutics Consortium, Critical Path Institute, Tucson, AZ, 2UNOS, Richmond, VA

    *Purpose: The Transplant Therapeutics Consortium established a real-world evidence workgroup evaluating the potential of supplementing internal control arms with external controls to understand the impact…
  • 2022 American Transplant Congress

    Impact of Sub-therapeutic Tacrolimus Troughs at Discharge from Index Admission on Short-Term Outcomes in Kidney Transplant Recipients Receiving Rabbit Anti-Thymocyte Globulin Induction

    X. Liu1, J. Trofe-Clark2, D. Sawinski3, B. Steiner1, S. Sharma1, S. Witek1, T. Fallah2, M. Norris2, C. Sammons2, G. Malat2

    1Pharmacy, Hosp of Univ of Pennsylvania, Philadelphia, PA, 2Penn Transplant Institute and Pharmacy Dept, Hosp of Univ of Pennsylvania, Philadelphia, PA, 3Penn Transplant Institute, Hosp of Univ of Pennsylvania, Philadelphia, PA

    *Purpose: Kidney transplant (KTx) recipients are often discharged with subtherapeutic tacrolimus (TAC) troughs due to short hospital lengths of stay (LOS) for index KTx admissions.…
  • 2022 American Transplant Congress

    The Performance of the Kidney Donor Profile Index in Predicting Outcomes for Kidney Transplant Recipients of Standard Criteria Donors: Results from a Brazilian Single-Center Cohort Study

    A. Morais, R. D. Foresto, J. Medina-Pestana, H. Tedesco-Silva, L. R. Requião-Moura

    Nephrology Division - Hospital do Rim, Universidade Federal de São Paulo, São Paulo, Brazil

    *Purpose: To evaluate the performance of the Kidney Donor Profile Index (KDPI) in predicting outcomes for kidney transplant recipients (KTR) of standard criteria donors (SCD)…
  • 2022 American Transplant Congress

    Evaluation of Renal Function After Donation in Living Marginal Kidney Donor

    S. Harada1, H. Sasaki2, Y. Takada2, D. Takamoto2, T. Hirano2, T. Kan1, Y. Yamagata1, H. Harada2, K. Minami1, K. Moriya1, H. Tanaka1

    1Urology, Sapporo City General Hospital, Sapporo, Japan, 2Kidney Transplant Surgery, Sapporo City General Hospital, Sapporo, Japan

    *Purpose: Chronic kidney-donor shortage is major concern in Japan where more than 90% of recipients received kidneys from living donor as kidney transplantation from deceased…
  • 2022 American Transplant Congress

    Safety and Efficacy of Darbepoetin Alfa Dosing Strategies in Renal Transplant Recipients

    J. A. Solis, A. Dao, T. Sam, T. Ma, A. F. Yango, B. V. Fischbach, N. Wilson

    Baylor University Medical Center, Dallas, TX

    *Purpose: Post-transplant anemia (PTA) is a common phenomenon in renal transplant recipients (RTR). There are currently no consensus guidelines for PTA, however patients are commonly…
  • 2022 American Transplant Congress

    A Nationwide, Multi-Center Survey of Lipid Management Strategies in Kidney Transplant Recipients

    J. Pandav, R. Saranu, S. Muhsin, Z. Solhjou, J. Y. Choi, S. Gabardi, A. Chandraker

    Renal division, Brigham and Women's Hospital, Boston, MA

    *Purpose: KDIGO 2013 guidelines for the management of lipid transplant recommend the use of statins in all kidney transplant recipients (KTRs), but with weak evidence…
  • 2022 American Transplant Congress

    The Impact of Obesity on Delayed Graft Function

    B. Shi1, T. Ying2, J. Xu1, J. M. Laurence1, S. Chadban1

    1Royal Prince Alfred Hospital, Camperdown, Australia, 2University of Sydney, Camperdown, Australia

    *Purpose: Obesity is increasingly prevalent among candidates for kidney transplantation. Outcomes for obese patients remain uncertain, as existing studies have shown conflicting short and longer-term…
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