ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2015 American Transplant Congress

    Once-a-Day Administration of CNIs, mTOR and MMF Is Safe in De Novo Renal Transplant Recipients: 1-Year Results of a Pilot Study

    G. Spagnoletti, M. Salerno, E. Favi, J. Pedroso, J. Romagnoli, F. Citterio.

    Surgery - Renal Transplant Unit, Catholic University of the Sacred Heart, Rome, Italy.

    Introduction. The half-lives of Tacrolimus, Everolimus, Cyclosporine and Mofetil Micofenolate (MMF) are respectively: 43, 30, 27 and 18 hours. Once-daily dosing of these drugs is…
  • 2015 American Transplant Congress

    Delayed Tacrolimus (TAC) to Rapamycin (RAPA) Conversion in Renal Transplant Recipients With DGF/SGF

    A. Haririan,1 D. Klassen,1 M. Keshtkar,1 C. Drachenberg,2 T. Dowling,3 E. Ramos,1 R. Ugarte,1 C. Cangro,1 M. Weir.1

    1Medicine, University of Maryland, Baltimore, MD; 2Pathology, University of Maryland, Baltimore, MD; 3Pharmacy, University of Maryland, Baltimore, MD.

    The role of conversion from TAC to RAPA early after kidney transplantation in patients with DGF/SGF in improving graft function and delaying chronic allograft dysfunction…
  • 2015 American Transplant Congress

    Plasma Cell Infiltration: General Overview of Clinical and Pathological Correlations in Renal Transplantation

    C. Nihei, F. Lemos, D. David, P. Souza, F. de Paula, W. Nahas, E. David-Neto.

    Transplantation Service, Hospital das Clinicas-University of São Paulo, São Paulo, SP, Brazil.

    Background and Objective: Plasma cells are known as the final effectors of humoral immune response. Their significance and clinical outcomes are still controversial in kidney…
  • 2015 American Transplant Congress

    Current Dialysis, Previous Kidney Transplant, and Autoimmune Disease Increase Risk for Abnormal Pap Smear in Women Undergoing Kidney Transplant Evaluation

    K. Chaung,1 Y. Zheng,1 A. Martella,2 J. Stoecker,1 D. Cote,1 J. Augustine,2 E. Sanchez,2 V. Humphreville,2 J. Ammori,2 K. Woodside.2

    1Case Western Reserve University School of Medicine, Cleveland, OH; 2University Hospitals, Cleveland, OH.

    The USPSTF recommends Pap smears every three years for women 21-65, with optional combination Pap smear and HPV testing every five years for women 30-65.…
  • 2015 American Transplant Congress

    Pre-Trasplant Perfusion With Mesenchymal Stromal Cells of Renal Graft Prevents Ischemia Injury Upregulating Gene Involved in Energy Saving

    V. Corradetti,1 S. Milanesi,1 E. Pattonieri,1 C. Rocca,1 T. Valsania,1 M. Gregorini,1 L. De Cecco,2 I. Benzoni,3 C. Bianco,3 M. Avanzini,4 M. Maestri,3 P. Esposito,1 T. Rampino,1 A. Dal Canton.

    1Unit of Nephrology, Dialysis and Transplantation, IRCCS Fondazione Policlinico San Matteo And University of Pavia, Pavia, Italy; 2Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milano, Italy; 3Unit of General Surgery, IRCCS Fondazione Policlinico San Matteo And University of Pavia, Pavia, Italy; 4Cell Factory Pediatric Oncohaematology, IRCCS Fondazione Policlinico San Matteo, Pavia, Italy.

    Background. Kidney ischemia from Donation after Circulatory Death shifts cells to anaerobic metabolism. Mesenchymal Stromal Cells (MSC) have immunomodulatory properties that are mediated by soluble…
  • 2015 American Transplant Congress

    Enhanced Production of Macrophage Chemoattractant Protein-1 (MCP-1) Within the Kidney in Brain Death Donors Predicts Recipient Allograft Function

    J. Chen, S. Antipenko, A. Zmijewska, R. Reed, J. Locke, R. Mannon.

    Medicine/Surgery, University of Alabama at Birmingham, Birmingham, AL.

    Brain death (BD) induces an intense pro-inflammatory state, which may impact recipient immunity and graft function after kidney transplantation. The identification of biomarkers predictive of…
  • 2015 American Transplant Congress

    The Effects of High-Risk Donors and Recipients on Scientific Registry of Transplant Recipients Program-Specific Outcomes

    J. Snyder,1 N. Salkowski,1 D. Zaun,1 J. Schold,2 A. Israni,1 B. Kasiske.1

    1Scientific Registry of Transplant Recipients, Minneapolis Medical Research Foundation, Minneapolis, MN; 2Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH.

    Public reporting of transplant program-specific outcomes may dissuade programs from accepting high-risk donors and recipients, and thereby restrict access to transplant. It has been proposed…
  • 2015 American Transplant Congress

    Investigation of Myocardial Function in Pediatric Transplant Recipients

    K. Sgambat, S. Clauss, M. Lasota, A. Moudgil.

    Children's National, Washington, DC.

    Purpose: In light of the major impact of cardiovascular morbidity on long-term transplant outcomes, a prospective controlled study was conducted to investigate changes in myocardial…
  • 2015 American Transplant Congress

    Urinary CXCL10 Independently Improves the Noninvasive Diagnosis of Antibody-Mediated Kidney Allograft Rejection

    M. Rabant,1,2 L. Amrouche,2,3 X. Lebreton,3 F. Aulagnon,3 A. Benon,2 V. Sauvaget,2 R. Bonifay,2 L. Morin,3 A. Scemla,3 M. Delville,3 F. Martinez,3 M. Timsit,4 J. Duong Van Huyen,1 C. Legendre,3 F. Terzi,2 D. Anglicheau.2,3

    1Pathology Department, Necker Hospital, Paris, France; 2INSERM U1151, Necker Hospital, Paris, France; 3Kidney Transplant Center, Necker Hospital, Paris, France; 4Urology Department, Necker Hospital, Paris, France.

    The urinary levels of CXCL9 and CXCL10 can noninvasively diagnose T cell-mediated rejection (TCMR) of renal allografts. Their performance as diagnostic/prognostic markers of antibody-mediated rejection…
  • 2015 American Transplant Congress

    Patient and Process-Level Factors Associated With Kidney Transplant Readmissions

    K. Covert, J. Fleming, C. Staino, J. Casale, K. Boyle, N. Pilch, H. Meadows, C. Mardis, J. McGillicuddy, C. Bratton, T. Srinivas, K. Chavin, P. Baliga, D. Taber.

    MUSC, Charleston, SC.

    Readmissions following kidney transplantation (KTX) are common, with complex etiologies. There is a lack of research exploring the potential of optimizing post-transplant processes to reduce…
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