2015 American Transplant Congress
Everolimus Conversion to Treat BK Virus Infection in Kidney Transplant Recipients
IntroductionmTORi's reduce BKV large T antigen expression in vitro and are associated with lower rates of BKV infection in clinical studies.MethodsPilot single center, randomized, open-label…2015 American Transplant Congress
The Occurrence of v- Lesions Is Not Associated With Decreased Graft Survival
Intimal arteritis (v-lesions) in kidney transplant biopsies has been believed to have major prognostic and diagnostic significance. We assessed the relationship of v-lesions to prognosis…2015 American Transplant Congress
CD28-Directed Therapy Prolongs Survival in a Non-Human Primate Kidney Transplant Model
Introduction. Costimulation blockade using belatacept has the potential to improve long-term renal function and reduce cardiovascular risk by avoiding calcineurin inhibitors, yet higher rates and…2015 American Transplant Congress
Depression of Complement Regulatory Factors in Human and Rat Renal Grafts in Association With Progress of Acute Cellular Rejection
Introduction and ObjectiveIt is commonly known that complements play important roles in antibody mediated rejection in renal transplantation. However, the association of complements with progression…2015 American Transplant Congress
Histologic Findings in Pre-transplant AT1Rab + ve Patients Point to an Increase in Sub-Intimal Fibrosis During Acute Rejection and in 12 mo. Protocol Renal Graft Biopsies
Previous reports have described an increase in arteritis during acute rejection (AR) in angiotensin II type 1 receptor antibody (AT1Rab) positive (ve+) kidney transplant recipients…2015 American Transplant Congress
Impact of Early Urinary Tract Infections on Renal Graft Function
Barnes Jewish Hospital, St Louis, MO.
Purpose: Describe the incidence of early urinary tract infections (UTI) after renal transplantation at a large academic transplant center. Evaluate the impact of early UTIs…2015 American Transplant Congress
De Novo Donor-Specific HLA Antibodies After Kidney Transplantation Are Associated With Donation After Circulatory Death and HLA-DQ Mismatch
Introduction: De novo donor-specific HLA-antibodies (dnDSA) have been associated with rejection and inferior kidney graft survival. The purpose of this study was to investigate the…2015 American Transplant Congress
Low Expanded Criteria Donor Listing Rates by Organ Procurement Organization Is Associated With Increased Differential in Waiting Time for Candidates Willing to Accept Marginal Organs in the US
Medicine, University of Virginia, Charlottesville, VA.
Organ procurement organization (OPO) listing rates for expanded criteria donor (ECD) kidneys vary greatly across the US. The goal of ECD listing is to shorten…2015 American Transplant Congress
Delayed Graft Function in Patients Receiving Alemtuzumab Induction Therapy
1The University of Toledo Medical Center, Toledo, OH; 2The Alliance for Paired Donation, Maumee, OH.
Alemtuzumab (Campath 1-H) is a humanized monoclonal antibody directed at the CD52 glycoprotein that is becoming more prevalent as a choice for induction. Delayed graft…2015 American Transplant Congress
Day of Week Influences Kidney Utilization
Department of Medicine, Columbia University Medical Center, New York, NY.
Background: From 2000 to 2013, 17% of all kidneys procured for transplantation from deceased organ donors in the United States were discarded. The high rate…
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