2015 American Transplant Congress
Eculizumab in the Treatment of Early Severe Acute Antibody Mediated Rejection Following HLA-Compatible Kidney Transplantation-Case Series
Severe early acute antibody-mediated rejection (AMR) is associated with poor allograft outcomes. Eculizumab is a humanized mouse monoclonal antibody against complement factor C5 that has…2015 American Transplant Congress
A Novel Maintenance Regimen With Calcineurin Inhibitor, MMF and Everolimus Initiated By Dual Induction Therapy With Anti-CD20/25 Antibodies in Renal Transplantation
Surgery III, Tokyo Women's Medical University Hospital, Shinjuku-ku,Tokyo, Japan.
【background】Calcineurin inhibitor (CNI), MMF and steroid has been the gold standard of maintenance regimen in renal transplantation (RTx). A line of new immunosuppressants has emerged…2015 American Transplant Congress
Pre-Transplant Weight Change and New-Onset Diabetes After Kidney Transplantation
Dept of Medicine, UCLA School of Medicine, Los Angeles, CA.
Background:We studied the association between pre-transplant weight change and new-onset diabetes after kidney transplant (NODAT).Methods:Using OPTN/UNOS data with follow-up to October, 2012, all adult (age>18…2015 American Transplant Congress
Incidence, Determinants and Outcome of Kidney Transplantation for End Stage Renal Disease After Heart Transplantation
Objectives: Progressive renal failure is a frequent complication following heart transplantation (HTx), is generally attributed to calcineurin inhibitor (CNI) based immunosuppression, and may result in…2015 American Transplant Congress
Gradual Warming Up Perfusion Post Static Cold Storage Reduces Renal Injury
We hypothesize that the sudden warm reperfusion after Cold Storage [CS] is detrimental for the graft and we therefore evaluated different warming-up procedures before reperfusion.Methods:Rat…2015 American Transplant Congress
High Within-Patient Variability in Tacrolimus Levels Is a Predictor of Late Rejection in Young Adult Kidney Transplant Recipients
Introduction: Non-adherence is an important risk factor for late rejection (rejection > 3 months post-transplant) and is the main reason why 17-29 year old kidney…2015 American Transplant Congress
Why Patients Are Unwilling to Ask for a Living Donor: A Mixed Methods Study
Multiple studies find that kidney patients are uncomfortable asking potential living donors to donate, but less is known about the specific reasons why not. This…2015 American Transplant Congress
Renal Mass as a Determinant Factor of Long-Term Post-Donation Anemia
Living kidney donors lose approximately 50% of renal mass when donating a kidney however, renal function recovers to within 60-70% of baseline within weeks to…2015 American Transplant Congress
Elevated Pre-Transplant Serum Troponin Is Associated With an Increased Risk of Mortality in Elderly Kidney Transplant Recipients
Introduction:Elderly patients with chronic kidney disease are nowadays more often considered for kidney transplantation although death rate is increased in this population compared to younger…2015 American Transplant Congress
Gene Expression of Kidney Biopsies Reveals Common Mechanisms of Rejection and a Cluster of Co-Expressed Genes Predictive of Long-term Outcomes
1The Scripps Research Institute, La Jolla; 2Northwestern University, Chicago.
Purpose: Acute rejection (AR) still affects 8-14% of kidney transplants and rates of 10-year graft loss remain unchanged in part due to chronic rejection (CR).…
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