2015 American Transplant Congress
Attenuating Racial Disparities in Kidney Transplantation Through the Use of Potent Immunosuppression Regimens
Medical University of South Carolina, Charleston, SC.
African-American (AA) kidney transplant (KTX) recipients have higher rates of graft loss, which may be partially attributed to higher immunologic risk. The aim of this…2015 American Transplant Congress
The Influence of Immunosuppressive Drugs On the Epithelial Microenvironment in Solid Organ Transplantation – Identification of Biomarker Candidates for Rejection Vs. Tolerance
In the context of kidney transplantation, NK cells may play an important role by targeting the allogeneic organ due to "missing-self recognition", which leads to…2015 American Transplant Congress
Increasing Tacrolimus Exposure to Minumize Chronic Rejection: How Can We Do It? What Are the Risks?
Background: Recent studies suggest that increased tacrolimus (TAC) exposure may help prevent production of donor specific HLA antibodies (DSAs) that mediate chronic rejection of renal…2015 American Transplant Congress
Post Hoc Subgroup Analysis of ZEUS: Outcome on Renal Function, Efficacy and Safety in Living-Donor Kidney Transplant Recipients After Conversion from a Calcineurin Inhibitor to an Everolimus Based Regimen: 5 Year Follow-Up Data
1ZEUS Study Group, Germany; 2ZEUS Study Group, Switzerland; 3Novartis, Pharma, Germany.
Background: To study renal function and patient outcome after 5 years in living donation subgroup of kidney de novo transplant recipients after conversion to an…2015 American Transplant Congress
Pubertal Development in Pediatric Kidney Transplant Patients Receiving Everolimus Or Conventional Immunosuppression
TOR inhibitors (mTORi) have been discussed to eventually influence pubertal development after pediatric kidney transplantation (Tx).This is the first trial to compare pubertal development in…2015 American Transplant Congress
Incidence and Characteristics of CMV Infection in High Risk (D+R-) Kidney Transplant Recipients and the Utility of Monthly Surveillance After Routine Prophylaxis
Internal Medicine, University of Pittsburgh, Pittsburgh, PA.
Cytomegalovirus (CMV) infection is the most common opportunistic viral infection after renal transplantation. Optimal duration of antiviral prophylaxis and the role of post prophylaxis surveillance…2015 American Transplant Congress
ABO-Incompatible Live Donor Kidney Transplants Inferior to ABO-Compatible Transplants, but Match Deceased Donor Results: Is Kidney Paired Donation the Answer?
Objective: Compare kidney allograft survival in ABO-incompatible (ABO-I) and ABO-compatible (ABO-C) live donor kidney transplant recipients.Methods: We analyzed UNOS database for patients who underwent a…2015 American Transplant Congress
Microvascular Inflammation in Early Protocol Biopsies of Renal Allografts in Cases of Chronic Active Antibody-Mediated Rejection
Aim:Chronic active antibody-mediated rejection (chronic ABMR) is one important cause of late-stage renal allograft loss. However, few reports have used protocol biopsy to observe changes…2015 American Transplant Congress
Pretransplant Antibodies Against Angiotensin II Type 1 Receptor in Renal Transplantation: Preliminary Data from the KNOW-KT Study
BackgroundThe antibodies (Abs) against angiotensin II type 1 receptor (AT1R) have been suggested as a risk factor for graft failure and acute rejection. However, incidence…2015 American Transplant Congress
Quantifying the Survival Benefit of HLA-Incompatible Kidney Transplantation: A Multi-Center Study
Surgery, Hopkins, Baltimore, MD.
A single center study has demonstrated a two-fold survival benefit of incompatible live donor kidney transplant (ILDKT) compared to remaining on dialysis. We sought to…
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