Articles tagged "Kidney transplantation"

2015 American Transplant Congress
Renal Transplantation in Aged Over 60 Years Demonstrates Compatible Clinical Outcomes to Younger Recipients
H. Cho,¹ H. Kim,¹ C. Baeck,¹ H. Yu,¹ D.-J. Han,² M. Jo,³ S.-K. Park.¹
¹Division of Nephrology, Department of Internal Medicine, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea; ²Department of Surgery, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea; ³Department of Preventive Medicine, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea.
Introduction: The aim of this study was comparing clinical outcomes of kidney transplantation between aged over 60 years and younger recipientsMethods: From 1993 to 2013,…
2015 American Transplant Congress
Perfusion Disturbances and Local Infarctions After Experimental Kidney Transplantation Corralte With the Duration of Cold Ischemia Time
S. Rong,¹ R. Chen,¹ M. Meier,⁴ B. Hensen,² H. Haller,¹ K. Hueper,² F. Gueler.¹
¹Nephrology, Hannover Medical School, Hannover, Germany; ²Radiology, Hannover Medical School, Hannover, Germany; ³Laboratory Medicine and Pathology, University of Alberta, Edmonton, Canada; ⁴Imaging Center, Hannover Medical School, Hannover, Germany.
Background: Kidney transplantation in mice is challenging but offers good translational models to study mechanisms of disease. In this study allogenic and isogenic kidney transplantation…
2015 American Transplant Congress
Everolimus Plus Reduced-Exposure Calcineurin Inhibitor Versus Mycophenolate Mofetil Plus Standard-Exposure Calcineurin Inhibitor: 2-Year Results in Living Donor Kidney Transplant Recipients
Y. Watarai,¹ N. Akutsu,² K. Saito,³ Y. Nakagawa,³ O. Kamisawa,⁴ T. Kenmochi.⁵
¹Transplant Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Japan; ²Surgery, Chiba-East Hospital, Chiba, Japan; ³Urology, Niigata University, Niigata, Japan; ⁴Medical Division, Novartis Pharma K.K., Tokyo, Japan; ⁵Transplant Surgery, Fujita Health University, Toyoake, Japan.
Purpose: To evaluate the long-term efficacy and safety of everolimus (EVR) plus reduced cyclosporine (rCsA) compared to mycophenolate mofetil (MMF) plus standard cyclosporine at 24…
2015 American Transplant Congress
Pharmacokinetics of Mycophenolic Acid (MPA) in Elderly Compared to Young Recipients in the First Year After Renal Transplantation. Data from the NEverOLd Trial
P. Romano,¹ F. Agena,² P. Ebner,¹ A. Triboni,² F. Ramos,² N. Galante,² F. Lemos,² N. Sumita,¹ E. David-Neto.²
¹Division of Central Laboratory, – Hospital das Clinicas – University of São Paulo School of Medicine, Sao Paulo, Brazil; ²Renal Transplantation Service, – Hospital das Clinicas – University of São Paulo School of Medicine, Sao Paulo, Brazil.
Elderly (≥60years) recipients are nowadays receiving renal transplants more frequently. The pharmacokinetics studies (PK) of immunosuppressive drugs in healthy volunteers, rarely, if ever, include old…
2015 American Transplant Congress
Preliminary Results of a Novel Induction Regimen Using Anti-Thymocyte Globulin (Rabbit) (rATG) Plus Basiliximab in a Pediatric Patient Population Undergoing Kidney Transplantation
D. Halleran,¹ S. Schurman, T. Welch, V. Whittaker.
¹Surgery, State University New York Upstate Medical University, Syracuse, NY; ²Pediatric Nephrology, State University New York Upstate Medical University, Syracuse, NY.
Purpose: We report the outcomes from single center experience with the novel induction regimen using rATG (3 mg/kg) in divided doses given on operative day…
2015 American Transplant Congress
Favorable Long-Term Outcome of Late-Onset CMV Disease in D+R- Kidney Transplant Recipients Treated With Universal Prophylaxis
H. Kaminski,¹ L. Couzi,^1,2 I. Garrigue,^3,4 J. Déchanet-Merville,² P. Merville.^1,2
¹Nephrologie-Transplantation-Dialyse, CHU Bordeaux, Bordeaux, France; ²Unité Mixte de Recherche 5164, Centre National de la Recherche Scientifique, Bordeaux, France; ³Laboratoire de Virologie, CHU Bordeaux, Bordeaux, France; ⁴Unité Mixte de Recherche 5234, Centre National de la Recherche Scientifique, Bordeaux, France.
Based on last international guidelines, both universal prophylaxis and preemptive strategies are viable approaches for the prevention of cytomegalovirus (CMV) disease after organ transplantation. Universal…
2015 American Transplant Congress
ABO-Incompatible Live Donor Kidney Transplants Inferior to ABO-Compatible Transplants, but Match Deceased Donor Results: Is Kidney Paired Donation the Answer?
J. Verbesey, M. Cooper, A. Gilbert, M. Grafals, P. Weems, J. Moore, S. Ghasemian, C. Nilubol, B. Javaid.
Georgetown University School of Medicine, MedStar Georgetown Transplant Institute, Kidney and Pancreas Transplant Program, Washington, DC.
Objective: Compare kidney allograft survival in ABO-incompatible (ABO-I) and ABO-compatible (ABO-C) live donor kidney transplant recipients.Methods: We analyzed UNOS database for patients who underwent a…
2015 American Transplant Congress
Microvascular Inflammation in Early Protocol Biopsies of Renal Allografts in Cases of Chronic Active Antibody-Mediated Rejection
T. Tsuji,¹ M. Yanai,¹ H. Itami,¹ Y. Ishii,¹ M. Akimoto,¹ N. Fukuzawa,² H. Harada,² Y. Fukasawa.¹
¹Demartment of Pathology, Sapporo City General Hospital, Sapporo, Japan; ²Department of Kidney Transplant Surgery, Sapporo City General Hospital, Sapporo, Japan.
Aim:Chronic active antibody-mediated rejection (chronic ABMR) is one important cause of late-stage renal allograft loss. However, few reports have used protocol biopsy to observe changes…
2015 American Transplant Congress
Pretransplant Antibodies Against Angiotensin II Type 1 Receptor in Renal Transplantation: Preliminary Data from the KNOW-KT Study
K. Huh,¹ J. Lee,¹ Y. Park,² Y. Kim,¹ C. Ahn.³
¹Department of Transplantation Surgery, Yonsei University Health System, Seoul, Republic of Korea; ²Department of Laboratory Medicine, Yonsei University Health System, Seoul, Republic of Korea; ³Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
BackgroundThe antibodies (Abs) against angiotensin II type 1 receptor (AT1R) have been suggested as a risk factor for graft failure and acute rejection. However, incidence…
2015 American Transplant Congress
Quantifying the Survival Benefit of HLA-Incompatible Kidney Transplantation: A Multi-Center Study
B. Orandi, X. Luo, A. Massie, J. Garonzik-Wang, B. Lonze, R. Ahmed, K. Van Arendonk, R. Montgomery, D. Segev.
Surgery, Hopkins, Baltimore, MD.
A single center study has demonstrated a two-fold survival benefit of incompatible live donor kidney transplant (ILDKT) compared to remaining on dialysis. We sought to…