2022 American Transplant Congress
Recipient Neutrophil Production of Myeloperoxidase is Required for NK Cell Activation During Acute Antibody Mediated Allograft Rejection
*Purpose: Dysregulated donor-specific antibody (DSA) responses are induced in B6.CCR5-/- mice transplanted with complete MHC mismatched A/J kidney allografts and are required for rejection of…2022 American Transplant Congress
Repeat Kidney Transplantation from Living Donors Offers Comparable Outcomes as First Transplantation
Department of Surgery, Samsung Medical Center, Seoul, Korea, Republic of
*Purpose: The number of patients relisted for repeat kidney transplantation is increasing due to prolonged survival after first transplantation. This study is designed to compare…2022 American Transplant Congress
Dialysis Patient Perspectives on Obesity as a Barrier to Kidney Transplantation
Drexel University, Philadelphia, PA
*Purpose: Although obesity is a known barrier to kidney transplantation (KT) and associated with delayed graft function and graft loss, guidance is lacking on optimal…2022 American Transplant Congress
Longitudinal Analysis of Donor-Derived Cell-Free DNA (dd-cfDNA) in En-Bloc Kidney Transplantation
*Purpose: The longitudinal dd-cfDNA patterns in en-bloc kidney transplant recipients have not been studied. It is unknown how the initial smaller mass of the two…2022 American Transplant Congress
Autophagy is an Important Factor in the Development of Fibrosis Following Renal Injury; Implications for Post-Transplant IFTA
*Purpose: Interstitial Fibrosis and Tubular Atrophy (IFTA) is the most common cause of long-term graft failure following renal transplant. There is currently no effective therapy.…2022 American Transplant Congress
Estrogen Receptor Beta Deletion is Protective in Renal Ischemia Reperfusion Injury but Pharmacologic Inhibition of Estrogen Receptor Beta is Not
*Purpose: Renal Ischemia Reperfusion Injury (IRI) contributes substantially to delayed graft function (DGF) in kidney transplantation. Prior work by our group has shown lower rates…2022 American Transplant Congress
Patient Preferences for Waiting Time and Kidney Quality: A Discrete Choice Experiment
Industrial Engineering and Management Sciences, Northwestern University, Evanston, IL
*Purpose: The purpose of this study was to elicit patient preferences involving tradeoffs between a lower quality kidney offered today and a higher quality, future…2022 American Transplant Congress
Post-Kidney Transplant Valacyclovir versus Valganciclovir for CMV Prophylaxis: A Randomized Controlled Trial
*Purpose: Valganciclovir (valG) is an effective CMV prophylactic agent post-kidney transplant (KTx) with significant side effects. Valacyclovir (valA) may be effective for CMV prophylaxis with…2022 American Transplant Congress
Comparing Long-Term Outcomes of Steroid-Based versus Steroid-Avoidant Immunosuppression in Pediatric Kidney Transplant Recipients
*Purpose: With increasing use of potent immunosuppressant (IS) medications, steroid-avoidant (SA) regimens are now commonly used for pediatric kidney transplant recipients (pKTs) to avoid potential…2022 American Transplant Congress
Higher Immunogenicity of a Third Heterologous Dose with BNT262b2 Mensanger RNA Vaccine Compared to a Homologous Dose in Kidney Transplant Recipients Fully Vaccinated with Inactivated Whole-Virion CoronaVac Vaccine
*Purpose: This study aims to compare the immunogenicity of a third dose of the heterologous BNT262b2 mRNA vaccine versus the homologous inactivated whole-virion CoronaVac vaccine…
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