Articles tagged "Kidney transplantation"

2015 American Transplant Congress
Early Weight Gain After Transplantation Can Cause Adverse Effect On Transplant Kidney Function
S. Choi, I.-K. Kim, S. Son, M. Ju.
Surgery, Gangnam Severance Hospital, Yonsei College of Medicine, Seoul, Korea.
Background: Outcomes of kidney transplant recipients with increased body mass index (BMI) remain controversial. We studied the relationship between change of BMI and transplant kidney…
2015 American Transplant Congress
Measuring Affinity of Polyclonal HLA-Specific Antibodies in Highly Sensitised Cases Can Serve as an Additional Biomarker to Guide Direct Transplantation
S. Daga,^1,2 D. Lowe,⁶ R. Buchli,³ J. Collard,³ A. Mulder,⁸ C. McMurtrey,^3,4 H. Moyse,⁷ N. Evans,⁷ N. Krishnan,² W. Hildebrand,^3,4 F. Claas,⁸ D. Briggs,⁵ D. Zehnder,^1,2 D. Mithcell,¹ R. Higgins.^1,2
¹Clinical Sciences Research Laboratories, University of Warwick, Coventry, United Kingdom; ²Renal Unit, University Hospital, Coventry and Warwickshire NHS Trust, Coventry, United Kingdom; ³Pure Protein LLC, Oklahoma; ⁴University of Oklahoma Health Science Center, Oklahoma City; ⁵Department of Histocompatibility and Immunogenetics, NHS Blood and Transplant, Birmingham, United Kingdom; ⁶Department of Histocompatibility and Immunogenetics, Royal Liverpool University Hospital, Liverpool, United Kingdom; ⁷School of Engineering, University of Warwick, Coventry, United Kingdom; ⁸Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, Netherlands.
Significant numbers of patients on transplant waiting lists in the UK are sensitised (43%). Direct transplantation across these HLA-specific antibodies using risk stratification strategies are…
2015 American Transplant Congress
Immune Phenotyping of Peripheral Blood Samples from the CTOT-10 Belatacept Study
Y. Suessmuth,¹ L. Stempora,¹ B. Johnson,¹ J. Cheeseman,¹ Y. Morrison,⁴ N. Bridges,⁴ D. Ikle,⁵ S. Tomlanovich,³ P. Stock,³ R. Mannon,² K. Newell,¹ C. Larsen,¹ A. Mehta.¹
¹Emory Transplant Center, Atlanta; ²University of Alabama, Birmingham; ³University of California San Francisco, San Francisco; ⁴NIAID/ NIH, Bethesda; ⁵Rho, Chapel Hill, NC.
The purpose of the CTOT-10 study is to evaluate belatacept as maintenance therapy, while minimizing calcineurin inhibitors and corticosteroids in renal transplantation. We designed mechanistic…
2015 American Transplant Congress
Lessons Learned from the Clinical Use of Normothermic Regional Perfusion (nRP) in Uncontrolled Donation After Circulatory Death (DCD)
C. Antoine,¹ E. Savoye,¹ F. Gaudez,² G. Cheisson,³ M. Videcoq,⁴ B. Barrou,⁵ National Steering Committee of Donation After Circulatory Death.¹
¹Medical and Scientific Department, Agence de la Biomedecine, LA Plaine Saint Denis, Saint Denis, France; ²Department of Urology, Saint Louis Hospital, Paris, France; ³Department of Anesthesia and Critical Care, Bicetre Hospital, Kremlin Bicetre, Val de Marne, France; ⁴Department of Transplantation, Edouard Herriot Hospital Group, Lyon, Rhones Alpes, France; ⁵Department of Anesthesia and Critical Care, Hôtel-Dieu Hospital, Nantes, Pays de la Loire, France; ⁶Department of Urology, University Hospital La Pitie, Paris, France.
The national protocol for the uDCD program restricts donor age < 55 y, no flow period < 30 min and total warm ischemia time (WIT)…
2015 American Transplant Congress
Identifying Predictors for 30-Day Readmission in Renal Transplant Recipients
J. Weber,¹ B. Astor,² D. Cray,³ A. Djamali,² D. Kaufman,⁴ D. Mandelbrot,² S. Parajuli,² M. Schanning,³ E. Snyder,¹ M. Mohamed.²
¹Surgical Nursing, UW Hospital & Clinics, Madison, WI; ²Department of Medicine, UW School of Medicine & Public Health, Madison, WI; ³Business Planning & Analysis Department, UW Hospital & Clinics, Madison, WI; ⁴Department of Surgery, UW School of Medicine & Public Health, Madison, WI.
Purpose: The aim of this study is to determine risk factors associated with 30-day hospital readmissions in renal transplant recipients.Methods: This single center longitudinal study…
2015 American Transplant Congress
Outbreak of Pandemic Influenza A (H1N1pdm) in a Kidney Transplant Unit – The Protective Effect of Vaccination
I. Helanterä,¹ V.-J. Anttila,² M. Lappalainen,³ M. Lempinen,¹ H. Isoniemi.¹
¹Department of Transplant and Liver Surgery, Helsinki University Central Hospital, Helsinki, Finland; ²Department of Infectious Diseases, Helsinki University Central Hospital, Helsinki, Finland; ³Department of Virology, Helsinki University Central Hospital, Helsinki, Finland.
Background: Seasonal influenza vaccination is recommended for patients with end-stage renal disease, although the efficacy of the vaccination among these patients is unknown. We characterize…
2015 American Transplant Congress
Prospective Measurement of Plasma Neutrophil Gelatinase-Associated Lipoprotein in Living Kidney Donors
Y. Yoon,¹ K. Choi,² D. Joo,³ K. Huh,³ M. Kim,³ S. Kim,³ Y. Kim,³ S. Yang,² W. Han.¹
¹Department of Urology, Yonsei University College of Medicine, Seoul, Korea; ²Department of Urology, CHA University, Seongnam-si, Korea; ³Department of Transplantation Surgery, Yonsei University College of Medicine, Seoul, Korea.
Introduction: Neutrophil gelatinase-associated lipocalin (NGAL) is a biomarker for acute kidney injury. This study was conducted to determine the clinical implications of perioperative plasma NGAL…
2015 American Transplant Congress
Live Kidney Donor Evaluation: Association of Race With Ineligibility
K. Kumar, A. Poon, A. Massie, A. Muzaale, T. Purnell, J. Tonascia, E. King, D. Segev.
Johns Hopkins, Baltimore.
Background: African American (AA) waitlist candidates face many barriers to identifying LKDs. However, even if AA candidates identify a potential donor, it is unclear whether…
2015 American Transplant Congress
Does Transversus Abdominis Plane Block Reduce Opioid Analgesic Requirements in the Post-Operative Period in Renal Transplant Recipients?
F. Afridi,¹ R. Coates,¹ S. Wright,² J. French,¹ D. Talbot,¹ S. Rita.²
¹Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, Tyne and Wear, United Kingdom; ²Department of Anesthesia, Freeman Hospital, Newcastle upon Tyne, Tyne and Wear, United Kingdom.
Introduction: Renal transplant recipients are a challenge where pain management is concerned. The theory that transversus abdominis plane (TAP) block provides additional analgesic benefit reducing…
2015 American Transplant Congress
Allo-Stimulated Interferon-γ Release and Natural Killer Cell Function Defines and Risk Stratifies Cancer Development in Kidney Transplant Recipients Who Have Cancer Post-transplantation
C. Hope,^1,2 A. Fuss,^1,2 W. Hanf,¹ P. Coates,^1,2 P. Heeger,³ R. Carroll.^1,2
¹The Centre for Clinical and Experimental Transplantation (CCET), Central Northern Adelaide Renal and Transplantation Services (CNARTS), Adelaide, South Australia, Australia; ²Medicine, The University of Adelaide, Adelaide, South Australia, Australia; ³Icahn School of Medicine, The Recanati-Miller Transplant Institute, New York City, NY.
Reducing immunosuppression is efficacious in primary prevention of cancer in Kidney Transplant Recipients (KTR) but can precipitate graft rejection. Conventional immunosuppressive drug monitoring fails to…