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Articles tagged "Kidney transplantation"

  • 2016 American Transplant Congress

    Associations of Risk Factors and Kidney Retransplant Outcomes Vary Between Three Common Induction Agents: Results from the Analysis of Over Ten-Thousand Cases in Ten Years.

    A. Santos, X. Wen, M. Casey, S. Rehman, K. Womer.

    Medicine, University of Florida, Gainesville, FL.

    BACKGROUND: There is no published study comparing the significance of risk factors for graft outcomes associated with common induction regimens combined with tacrolimus and mycophenolate…
  • 2015 American Transplant Congress

    Immune Reconstitution in Recipients of Living Donor Kidney/Hematopoietic Stem + Facilitating Cell Transplants

    J. Leventhal,1 M. Elliott,2 E. Yolcu,2 L. Bozulic,3 D. Tollerud,3 J. Mathew,1 I. Konieczna,1 M. Ison,1 M. Badder,3 M. Abecassis,1 J. Miller,1 L. Gallon,1 S. Ildstad.3

    1Comprehensive Transplant Center, Northwestern Memorial Hospital, Chicago, IL; 2University of Louisville, Institute for Cellular Therapeutics, Louisville, KY; 3Regenerex, LLC, Louisville, KY.

    We report the long-term results from a reduced-intensity nonmyeloablative conditioning approach to establish high levels of donor chimerism without graft-versus-host disease (GVHD) in mismatched related…
  • 2015 American Transplant Congress

    Renal Outcomes of Cross Match Positive Simultaneous Liver Kidney (SLK) Transplant Recipients Compared to Cross Match Positive Kidney Allograft Recipients

    S. Vaishnav,1 T. Taber,1 W. Goggins,2 S. Nagaraju,2 J. Fridell,2 A. Sharfuddin,1 M. Yaqub,1 D. Mishler,1 M. Mujtaba.1

    1IUSM, IU Health, Indianapolis, IN; 2Surgery, Transplant, Indiana University School of Medicine, Indianapolis, IN.

    The protective role of liver in cross-match(XM) positive SLK recipients and its impact on the incidence of renal antibody mediated rejection (AMR) is unclear.A retrospective…
  • 2015 American Transplant Congress

    Is Pretransplant Anti-A/B Antibody Removal Prerequisite for Successful ABO Incompatible Kidney Transplantation in Children?

    S. Shishido,1 T. Kawamura,1 Y. Hamasaki,2 Y. Takahashi,1 Y. Hyodo,1 Y. Itabashi,1 H. Nihei,1 T. Yonekura,1 Y. Inaba,2 Y. Yoshida,2 K. Sakai,1 A. Aikawa.1

    1Nephrology, Toho University, School of Medicine, Tokyo, Japan; 2Pediatric Nephrology, Too University, School of Medicine, Tokyo, Japan.

    Purpose: We have recently demonstrated that the long-term outcome of ABO incompatible living donor kidney transplantation (ABOiKT) in children was comparable to those of ABO…
  • 2015 American Transplant Congress

    Predicting Graft Loss in a Population of Kidney Transplant Patients Diagnosed With ABMR/TG

    J. Reeve,1 P. Halloran.1

    1Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB, Canada; 2Medicine, University of Alberta, Edmonton, AB, Canada.

    ABMR is the main cause of late graft loss in kidney transplants. Our goal was to determine the variables most strongly predictive of graft loss…
  • 2015 American Transplant Congress

    Impact of Community Risk on Early Hospital Readmission Following Kidney Transplant

    E. King,1 L. Kucirka,1 M. McAdams-DeMarco,1,2 A. Massie,1,2 J. Schold,3 D. Segev.1,2

    1Surgery, Johns Hopkins University, School of Medicine, Baltimore, MD; 2Epidemiology, Johns Hopkins University, School of Public Health, Baltimore, MD; 3Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH.

    Background: Early hospital readmission (EHR) is associated with increased morbidity, mortality, and cost in kidney transplantation (KT). Community risk may be associated with EHR above…
  • 2015 American Transplant Congress

    Six Year Follow-Up of a Phase 2 Clinical Trial to Induce Tolerance in Mismatched Living Donor Renal Transplant Recipients

    J. Leventhal, M. Abecassis, L. Gallon, J. Galvin, J. Mehta, K. Ravindra, D. Tollerud, M. Elliott, S. Ildstad.

    Comprehensive Transplant Center, Northwestern Memorial Hospital, Chicago, IL; Duke University, Durham, NC; Institute for Cellular Therapeutics, University of Louisville, Louisville, KY; Regenerex, LLC, Louisville, KY.

    27 subjects have been transplanted in a phase 2 protocol (IDE 13947) based upon tolerogenic CD8+/TCR- facilitating cells (FCRx) and 200 cGy TBI-based nonmyeloablative conditioning…
  • 2015 American Transplant Congress

    Everolimus Versus Mycophenolate for Recipients of Kidney Transplants from Expanded Criteria Donors (ECD) Receiving Anti-Thymocyte Globulin and Tacrolimus

    H. Tedesco-Silva,1 C. Felipe,1 A. Ferreira,1 M. Cristelli,1 A. Bessa,1 P. Ueno,1 T. Sandes- Freitas,1 G. Bassos,1 W. Aguiar,2 H. Proença,3 J. Medina-Pestana.1

    1Nephrology, Hospital do Rim UNIFESP, Sao Paulo, Brazil; 2Urology, Hospital do Rim UNIFESP, Sao Paulo, Brazil; 3Pathology, UNIFESP, Sao Paulo, Brazil.

    Introduction: Recipients of kidneys recovered from expanded criteria donors are at higher risk to develop delayed graft function (DGF) and acute rejection (AR), leading to…
  • 2015 American Transplant Congress

    Survival Benefit of Kidney Transplant Among HIV+ Waitlist Candidates

    J. Locke,1 S. Gustafson,2 C. Durand,3 J. Snyder,2 B. Shelton,1 R. Reed,1 P. MacLennan,1 S. Mehta,1 A. Nellore,1 D. Segev.2,3

    1University of Alabama, Birmingham, AL; 2Scientific Registry of Transplant Recipients (SRTR), Minneapolis Medical Research Foundation, Minneapolis, MN; 3Johns Hopkins University, Baltimore, MD.

    Chronic diseases, such as end-stage renal disease (ESRD), are now the leading causes of death among HIV+ patients. Multiple studies have demonstrated the efficacy of…
  • 2015 American Transplant Congress

    Pregnancy Outcomes in Female Kidney Transplant Recipients: Does Ethnicity Have an Influence?

    S. Constantinescu,1,2 L. Coscia,2 D. Armenti,2 P. Axelrod,1 M. Ghanta,1 S. Rao,1 M. Moritz.2,3

    1Temple University School of Medicine, Philadelphia; 2National Transplantation Pregnancy Registry, Gift of Life Institute, Philadelphia; 3Lehigh Valley Health Network, Allentown.

    The purpose of this study was to analyze pregnancy outcomes in female kidney transplant recipients by ethnicity. Data were collected by the National Transplantation Pregnancy…
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