Articles tagged "Kidney transplantation"

2016 American Transplant Congress
C1q Assays Are Not Associated with Clinical or Serologic Endpoints.
A. Gilbert,¹ M. Zaheer,¹ O. Timofeeva,² M. Awwad,² D. Li,² S. Rosen-Bronson,² B. Javaid,¹ M. Grafals,¹ J. Verbesey,¹ P. Abrams,¹ M. Cooper.¹
¹Medicine, MedStar Georgetown Transplant Institute, Washington, DC; ²Pathology, MedStar Georgetown Transplant Institute, Washington, DC; ³Surgery, MedStar Georgetown Transplant Institute, Washington, DC.
PURPOSE: The c1q assay has been proposed as a potential adjunct to standard donor specific antibody (DSA) testing designed to improve the specificity to identify…
2016 American Transplant Congress
Immune Tolerance Monitoring in Renal Allograft Tolerance Induced by Transient Mixed Chimerism in Nonhuman Primates and Humans.
K. Hotta, T. Oura, K. Crisalli, D. Sachs, B. Cosim, T. Kawai.
Center for Transplantation Science, Massachusetts General Hospital, Boston, MA.
Background: Successful induction of allograft tolerance in MHC-mismatched kidney transplantation has been achieved after induction of transient chimerism in both nonhuman primates (NHP) and humans.…
2016 American Transplant Congress
Tacrolimus Dosing, Trough Concentrations and Dose Adjustments Compared Between Two Generic Formulations in Adult Kidney Transplant Recipients.
D. Taber, V. Phan, A. Wilton, N. Pilch, H. Meadows, J. Fleming, C. Mardis, A. Mardis, C. Bratton, K. Chavin, J. McGillicuddy, S. Nadig, P. Baliga.
MUSC, Charleston, SC.
Objective: The aim of this study was to assess if changing between two different formulations of generic tacrolimus ([tac] Mylan® and Dr. Reddy's Lab®) impacts…
2016 American Transplant Congress
Vaccination Status and Titers Before and After Pediatric Renal Transplantation: An Analysis of the CERTAIN Registry.
B. Höcker,¹ M. Aguilar,¹ P. Schnitzler,² L. Pape,² L. Dello Strologo,² N. Webb,² M. Bald,² G. Genc,² H. Billing,² J. König,² A. Büscher,² F. Thiel,² S. Marks,² M. Pohl,² M. Wigger,² R. Topaloglu,² A. Fichtner,¹ S. Rieger,¹ K. Krupka,¹ B. Tönshoff.¹
¹University Children's Hospital, Heidelberg, Germany; ²CERTAIN Research Community, Italy, United Kingdom, Turkey, Germany.
Purpose:Prevention of systemic viral and bacterial infections by effective vaccination in kidney allograft recipients is of vital importance, but data on the vaccination status in…
2016 American Transplant Congress
Quality Improvement Initiative to Provide Comprehensive Pharmacy Services to Kidney Transplant Patients at a Small Transplant Center.
J. Dickson,¹ W. Vincent III,¹ L. Wu,² J. Thurman,¹ J. Francis,³ M. Nuhn.⁴
¹Pharmacy, Boston Medical Center, Boston, MA; ²Northeastern University, Boston, MA; ³Renal Medicine, Boston Medical Center, Boston, MA; ⁴Transplant Surgery, Boston Medical Center, Boston, MA.
Purpose: Previously, kidney transplant pharmacy services at our institution were limited to medication profile review before and after transplant surgery. Following an OPTN accreditation site…
2016 American Transplant Congress
Treatment of Post-Transplant Focal Glomerulosclerosis: The Effect on Histopathology Lesions and Podocyte Foot Process Effacement.
K. Koutroutsos,¹ J. Moss,² L. Moran,² T. Cook,² R. Charif,¹ D. Taube,¹ C. Roufosse,² M. Loucaidou.¹
¹Renal and Transplant Centre, Imperial Healthcare NHS Trust, London, United Kingdom; ²Department of Histopathology, Imperial Healthcare NHS Trust, London, United Kingdom.
Background: Post-transplant Focal Segmental Glomerulosclerosis (FSGS) is associated with increased risk for renal allograft failure. It has been reported in the literature that podocyte foot…
2016 American Transplant Congress
Stratifying Skin Versus Non-Skin Cancer Risk Post-Kidney Transplantation According to Patient Characteristics.
F. Jackson-Spence,¹ H. Gillott,¹ S. Tahir,¹ F. Evison,² J. Nath,³ A. Sharif.³
¹University of Birmingham Medical School, Birmingham, United Kingdom; ²Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom; ³Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom.
Introduction Cancer is a significant cause of morbidity and mortality after kidney transplantation but risk differs e.g. non-melanoma skin cancers have a better prognosis compared…
2016 American Transplant Congress
Diabetes Mellitus and Kidney Transplant Outcomes.
A. Mehrnia,¹ A. Wang,¹ W. Chaiwatcharayut,² E. Huang,¹ S. Bunnapradist.¹
¹Nephrology, University of California-Los Angeles, Los Angeles, CA; ²Internal Medicine, Albert Einstein University, Bronx, NY.
Background:This study investigates the impact of pre-existing (PDM) and new onset diabetes (NODAT) on the graft and patient survival after kidney transplant.Methods:The UNOS database was…
2016 American Transplant Congress
Examining the Risk for Post-Transplant Viral Infections and Lymphoproliferative Disorder (PTLD) in Kidney Transplant Patients (Pts) Receiving Calcineurin Inhibitor-Based Immunosuppression (CNI-IS) Compared to Belatacept (CTLA4Ig).
B. Shin, J. Choi, J. Kahwaji, S. Ge, D. Thomas, A. Vo, O. Galera, R. Villicana, A. Peng, S. Jordan, M. Toyoda.
Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.
Introduction: CTLA4Ig is a novel IS agent that acts through costimulatory blockade of T-cells and obviates the need for CNI. Despite benefits in improving renal…
2016 American Transplant Congress
The First Impressions: A Study in Pre and Post-Implantation Renal Grafts for Early Detection Markers of Delayed Graft Function and Recovery.
S. Bontha,¹ L. Suh,¹ P. Dormish,¹ R. Gehrau,¹ E. Rhone,¹ L. Gallon,³ A. King,² C. Dumur,² D. Maluf,¹ V. Mas.¹
¹UVA, Charlottesville; ²VCU, Charlottesville; ³Northwestern University, Chicago.
Background: Delayed graft function (DGF) is mainly a consequence of ischemia and reperfusion injury (IRI) resulting in acute tubular necrosis. The degree of IRI is…