ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2016 American Transplant Congress

    A Comprehensive Biomarker Study to Compare Tacrolimus and Mycophenolic Acid versus Half-Dose Tacrolimus and Everolimus in De Novo Kidney Transplant Patients in the Novartis US92 Study.

    J. Klepacki,1 J. Klawitter,1 J. Klawitter,1 A. Karimpour-fard,2 E. Anderson,1 G. Ingle,3 D. Patel,3 K. Johnson,4 D. Cibrik,4 U. Christians.1

    1University of Colorado Denver, Aurora, CO; 2University of Colorado Denver, Aurora, CO; 3Novartis Pharmaceuticals, East Hannover, NJ; 4University of Michigan, Ann Arbor, MI.

    In this exploratory biomarker sub-study, a comprehensive combined targeted/ non-targeted metabolomics and targeted proteomics approach was used to assess potential differences between the everolimus+ low-dose…
  • 2016 American Transplant Congress

    Do We Need an Individually Tailored Immunosuppression Strategy for Living Donor Kidney Transplant Recipients with PreTransplant Donor Specific Antibodies? A Retrospective Analysis.

    S. Bhutani,1 A. Ponnusamy,2 Q. Tak,1 S. Shah,1 J. Worthington,1 A. Summers,1 K. Poulton,1 D. Van Dellen,1 M. Morton,1 M. Picton.1

    1Department of Renal & Transplant Medicine, Manchester Royal Infirmary, Manchester, United Kingdom; 2Department of Renal Medicine, Royal Hospital Preston, Preston, United Kingdom.

    Introduction:Pre-Transplant Microbead donor HLA specific antibody(DSA) positive but cell crossmatch negative transplants are considered to be at increased immunological risk. This study aimed to address…
  • 2016 American Transplant Congress

    Eversion Endarterectomy of the Deceased Donor Renal Artery to Prevent Kidney Discard.

    M. Khan, K. Jones, H. El-Hennawy, A. Farney, J. Rogers, G. Orlando, R. Stratta.

    Surgery, Wake Forest, Winston-Salem, NC.

    Deceased donor (DD) kidneys exhibiting severe atherosclerosis with hard ulcerative occlusive plaque extending into the renal artery (RA) may represent a contraindication to utilization. Limited…
  • 2016 American Transplant Congress

    Infections in De Novo Kidney Transplant Recipients Treated with the RANKL Inhibitor Denosumab: A Post-Hoc Analysis of the POSTOP Clinical Trial (NCT01377467).

    M. Bonani,1 D. Frey,2 J. Brockmann,3 T. Fehr,1 T. Müller,1 N. Graf,4 R. Wüthrich.1

    1Division of Nephrology, University Hospital Zurich, Zurich, Switzerland; 2Division of Rheumatology, University Hospital Zurich, Zurich, Switzerland; 3Division of Visceral and Transplantation Surgery, University Hospital Zurich, Zurich, Switzerland; 4Graf Biostatistics, Winterthur, Switzerland.

    Background: A major cause of morbidity and mortality in kidney transplant recipients are infections. In this post-hoc analysis of the POSTOP study we assessed all…
  • 2016 American Transplant Congress

    Baseline Donor Specific Antibody (DSA) More Predictive of Chronic Antibody Mediated Rejection (CAMR) Than the Change in DSA Over Time.

    D. Mitema,1 W. Cheungpasitporn,1 M. Stegall,1 F. Cosio,1 M. Gandhi,2 C. Schinstock.1

    1Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN; 2Division of Transfusion Medicine, Mayo Clinic, Rochester, MN.

    Introduction: Although therapies are available to at least temporarily reduce DSA, the change in DSA naturally post-transplant remains unknown. We aim to study the serial…
  • 2016 American Transplant Congress

    Serum Levels of Soluble Myeloid Antigens After Kidney Allograft Transplantation.

    I. Striz, E. Cecrdlova, A. Sekerkova, J. Slatinska, V. Svachova, O. Viklicky.

    Institute for Clinical and Experimental Medicine (IKEM), Prague, Czech Republic.

    Mononuclear phagocytes and neutrophils play a key role in early responses against the transplanted kidney allograft. It is expected that during the reperfusion of kidney…
  • 2016 American Transplant Congress

    The Simplified EPTS Score: Who Wins and Who Loses?

    J. Schold, E. Poggio, R. Fatica, S. Flechner, L. Buccini, D. Goldfarb.

    Cleveland Clinic, Cleveland, OH.

    The New Kidney Allocation System includes provisions that candidates with EPTS score in the lowest 20% (indicating best expected survival) have access to the highest…
  • 2016 American Transplant Congress

    Pre-Emptive Kidney Transplantation with Living- Donor and Concomitant Unilateral Nephrectomy in Patients with Autosomal-Dominant Polycystic Kidney Disease: A Safe Strategy?

    C. Michel,1 F. Audenet,1 M. Ariane,1 C. Legendre,2 D. Joly,2 A. Méjean,1 M.-O. Timsit.1

    1Urology, Hôpital Européen Georges Pompidou, Paris, France; 2Nephrology and Transplantation, Hôpital Necker, Paris, France.

    Objectives. Because the timing of the nephrectomy still remains unclear, we studied the complications and outcomes of unilateral nephrectomy and concomitant pre-emptive kidney transplant with…
  • 2016 American Transplant Congress

    Associations of Perfusate Biomarkers and Pump Parameters with Delayed Graft Function and Deceased-Donor Kidney Allograft Function.

    C. Parikh,1 I. Hall,1 R. Bhangoo,2 J. Ficek,1 P. Abt,3 H. Thiessen-Philbrook,1 H. Lin,1 M. Bimali,1 P. Murray,4 V. Rao,1 B. Schröppel,5 M. Doshi,6 F. Weng,7 P. Reese.3

    1Yale University School of Medicine, New Haven, CT; 2University of Arizona College of Medicine, Phoenix, AZ; 3University of Pennsylvania, Philadelphia, PA; 4University College Dublin, Dublin, Ireland; 5Mount Sinai School of Medicine, New York, NY; 6Wayne State University, Detroit, MI; 7Barnabas Health, Livingston, NJ.

    Hypothermic machine perfusion (HMP) is increasingly used in deceased-donor kidney transplantation, but controversy exists regarding the value of perfusion biomarkers and pump parameters for assessing…
  • 2016 American Transplant Congress

    Does Drain Placement Reduce the Risk of Peri-Graft Collections and Wound Complications After Kidney Transplant?

    S. Cimen,1 S. Cimen,1 K. Tennankore,2 A. Imamoglu,3 I. Alwayn.1

    1Department of Surgery, Dalhousie University, Halifax, NS, Canada; 2Department of Nephrology, Dalhousie University, Halifax, NS, Canada; 3Department of Urology, Yildirim Beyazit EAH, Ankara, Turkey.

    Introduction: Peri-graft collections and wound complications are common after kidney transplantation. Currently, it is unclear whether intraoperative drain placement can reduce the risk of peri-graft…
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