ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2016 American Transplant Congress

    Treatment of Post-Transplant Focal Glomerulosclerosis: The Effect on Histopathology Lesions and Podocyte Foot Process Effacement.

    K. Koutroutsos,1 J. Moss,2 L. Moran,2 T. Cook,2 R. Charif,1 D. Taube,1 C. Roufosse,2 M. Loucaidou.1

    1Renal and Transplant Centre, Imperial Healthcare NHS Trust, London, United Kingdom; 2Department of Histopathology, Imperial Healthcare NHS Trust, London, United Kingdom.

    Background: Post-transplant Focal Segmental Glomerulosclerosis (FSGS) is associated with increased risk for renal allograft failure. It has been reported in the literature that podocyte foot…
  • 2016 American Transplant Congress

    Stratifying Skin Versus Non-Skin Cancer Risk Post-Kidney Transplantation According to Patient Characteristics.

    F. Jackson-Spence,1 H. Gillott,1 S. Tahir,1 F. Evison,2 J. Nath,3 A. Sharif.3

    1University of Birmingham Medical School, Birmingham, United Kingdom; 2Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom; 3Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom.

    Introduction Cancer is a significant cause of morbidity and mortality after kidney transplantation but risk differs e.g. non-melanoma skin cancers have a better prognosis compared…
  • 2016 American Transplant Congress

    Diabetes Mellitus and Kidney Transplant Outcomes.

    A. Mehrnia,1 A. Wang,1 W. Chaiwatcharayut,2 E. Huang,1 S. Bunnapradist.1

    1Nephrology, University of California-Los Angeles, Los Angeles, CA; 2Internal Medicine, Albert Einstein University, Bronx, NY.

    Background:This study investigates the impact of pre-existing (PDM) and new onset diabetes (NODAT) on the graft and patient survival after kidney transplant.Methods:The UNOS database was…
  • 2016 American Transplant Congress

    Examining the Risk for Post-Transplant Viral Infections and Lymphoproliferative Disorder (PTLD) in Kidney Transplant Patients (Pts) Receiving Calcineurin Inhibitor-Based Immunosuppression (CNI-IS) Compared to Belatacept (CTLA4Ig).

    B. Shin, J. Choi, J. Kahwaji, S. Ge, D. Thomas, A. Vo, O. Galera, R. Villicana, A. Peng, S. Jordan, M. Toyoda.

    Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.

    Introduction: CTLA4Ig is a novel IS agent that acts through costimulatory blockade of T-cells and obviates the need for CNI. Despite benefits in improving renal…
  • 2016 American Transplant Congress

    The First Impressions: A Study in Pre and Post-Implantation Renal Grafts for Early Detection Markers of Delayed Graft Function and Recovery.

    S. Bontha,1 L. Suh,1 P. Dormish,1 R. Gehrau,1 E. Rhone,1 L. Gallon,3 A. King,2 C. Dumur,2 D. Maluf,1 V. Mas.1

    1UVA, Charlottesville; 2VCU, Charlottesville; 3Northwestern University, Chicago.

    Background: Delayed graft function (DGF) is mainly a consequence of ischemia and reperfusion injury (IRI) resulting in acute tubular necrosis. The degree of IRI is…
  • 2016 American Transplant Congress

    Enhanced Recovery After Kidney Transplantation: 48 Hour Length of Stay in Living and Deceased Donor Transplant Recipients.

    O. Ojogho, J. Mejia, S. Bani-Hani, B. Dieter, R. Carson.

    Kidney Transplant Program, Providence Sacred Heart Medical Center and Chldren's Hospital, Spokane, WA.

    BACKGROUND: Enhanced recovery after kidney transplantation is a desired outcome with potential value-enhancing benefits of reduced length of stay (LOS), costs, and risk of nosocomial…
  • 2016 American Transplant Congress

    HLA Identical or Haploidentical Combined Kidney and Bone Marrow Transplantation for Multiple Myeloma with End-Stage Renal Failure.

    T. Kawai,1 Y.-B. Chen,1 M. Sykes,2 C. Benedict,1 N. Tolkoff-Rubin,1 B. Day,1 S. McAfee,1 K. Ballen, S. David,1 T. Spitzer.1

    1Massachusetts General Hospital, Boston; 2Columbia University, New York.

    Patients with multiple myeloma (MM) who developed end-stage renal disease (ESRD) are generally not eligible for either kidney transplantation or allogeneic stem-cell transplant. We performed…
  • 2016 American Transplant Congress

    NK Cells Play a Critical Role in Mediating Inflammation and Graft Failure During Antibody-Mediated Rejection of Kidney Allografts.

    T. Tanaka,1,2 N. Kohei,1 N. Dvorina,1 A. Valujskikh,1 W. Baldwin 3rd,1 R. Fairchild.1

    1Department of Immunology, Cleveland Clinic, Cleveland, OH; 2Department of Urology, Sapporo Medical University School of Medicine, Sapporo, Japan.

    While the incidence of antibody-mediated kidney graft rejection has increased, the key cellular and molecular participants underlying this graft injury remain unclear. We have previously…
  • 2016 American Transplant Congress

    Offering HCV-Positive Kidneys to HCV-Negative Patients on the Kidney Transplant Waitlist Is Lifesaving: Results of a Markov Model.

    D. Goldberg, P. Reese, V. Potluri, F. Scott.

    Medicine, University of Pennsylvania, Philadelphia, PA.

    Background: Patients with ESRD on the transplant waitlist face substantial risks of dying without a transplant. Because 2/3 of kidneys from hepatitis C virus (HCV)-positive…
  • 2016 American Transplant Congress

    Denosumab Prevents Bone Mineral Density Loss in De Novo Kidney Transplant Recipients: Results from a Randomized Controlled Trial.

    M. Bonani,1 D. Frey,2 J. Brockmann,3 T. Fehr,1 T. Müller,1 N. Graf,4 R. Wüthrich.1

    1Division of Nephrology, University Hospital Zurich, Zurich, Switzerland; 2Division of Rheumatology, University Hospital Zurich, Zurich, Switzerland; 3Division of Visceral and Transplantation Surgery, University Hospital Zurich, Zurich, Switzerland; 4Graf Biostatistics, Winterthur, Switzerland.

    Background: Kidney transplantation is associated with bone loss and an increased risk of fracture. Since current therapeutic options to prevent bone loss are limited we…
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