ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2016 American Transplant Congress

    Short Term Changes in HRQOL Following Kidney Transplantation.

    I. Olorundare, H. Ying, M. McAdams-DeMarco, D. Segev.

    JHU, Baltimore.

    Health-Related Quality of Life (HRQOL) is a patient-centered outcome that measures the impact of a disease and its treatment. This is particularly relevant to those…
  • 2016 American Transplant Congress

    Renal Outcome with Eculizumab in Patients with aHUS with Native and Transplanted Kidneys: Pooled Analysis of 100 Patients.

    C. Legendre,1 J. Campistol,2 T. Feldkamp,3 J. Wang,4 G. Remuzzi,5 L. Weekers,6 N. Sheerin.7

    1Université Paris Descartes & Hôpital Necker, Paris, France; 2Hospital Clinic, University of Barcelona, Barcelona, Spain; 3University Hospital Schleswig-Holstein, Kiel, Germany; 4Alexion Pharmaceuticals, Inc., Cheshire, CT; 5IRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Bergamo, Italy; 6CHU de Liège, Liège, Belgium; 7Newcastle University, Newcastle upon Tyne, United Kingdom.

    Purpose: aHUS often progresses to ESRD and requires transplant (tx). Eculiumab (ECU), a terminal complement inhibitor, inhibits TMA irrespective of tx status. We evaluated outcomes…
  • 2016 American Transplant Congress

    De Novo Anti-HLA DSA Characteristics and Subclinical Antibody Mediated Kidney Allograft Injuries.

    T. Yamamoto, Y. Watarai, A. Takeda, M. Okada, M. Tsujita, T. Hiramitsu, N. Goto, S. Narumi, K. Morozumi, K. Uchida, T. Kobayashi.

    Nagoya daini red cross hospital, Nagoya, Japan.

    Background It has been reported that de novo donor-specific HLA antibody (dn DSA) production is associated with chronic antibody-mediated rejection (CAMR) which leads to poor…
  • 2016 American Transplant Congress

    A Non-Invasive Blood Transcriptional Assay, Ksort, Monitors Alloimmune Response in the Sailor Randomized Multicenter Trial.

    J. Ekberg,1 B. Jespersen,2 K. Skov,2 M. Sarwal,3 T. Sigdel,3 S. Hsieh,3 P. Lindner.1

    1Transplantation, Sahlgrenska University Hospital, Gothenburg, Sweden; 2Nephrology, Skejby Hospital, Aarhus, Denmark; 3Surgery, University of California, San Francisco.

    Non-invasive diagnosis and prediction of acute rejection (AR) is a critical unmet need. A In a randomized multicenter trial of 222 renal transplant recipients a…
  • 2016 American Transplant Congress

    A Kidney Paired Donation Standard Acquisition Charge Pilot Program.

    M. Rees,1 L. Reece,2 S. Rees,2 B. Crandall,2 A. Leichtman.4

    1UT, Toledo; 2APKD, Perrysburg; 3Arbor Res, Ann Arbor.

    Background/Purpose: A national non-profit Kidney Paired Dontion (KPD) organization undertook a demonstration project to redesign payment for KPD transplants with a payment model similar to…
  • 2016 American Transplant Congress

    Recovery of eGFR in Both Donors and Recipients After Living Donor Kidney Transplantation.

    J. Verbesey, A. Gilbert, A. Li, M. Reissmann, N. Foreman, M. Grafals, B. Javaid, P. Abrams, S. Ghasemian, M. Cooper.

    MedStar Georgetown Transplant Institute, Washington, DC.

    Purpose: LD kidney donation provides a much needed resource for patients with end stage renal disease. Providing adequate renal mass to the recipient (R) is…
  • 2016 American Transplant Congress

    Pathogenic Role of Anti-HLA Antibodies on Endothelial Progenitor Cell Dysfunction of Highly Sensitized Kidney Transplanted Patients.

    V. Cantaluppi,1 S. Dellepiane,2 D. Medica,2 G. Tognarelli,2 M. Quaglia,1 C. Musetti,1 A. Airoldi,1 L. Biancone.2

    1Nephrology, Dialysis and Kidney Transplantation Unit, University of Eastern Piedmont "A. Avogadro", Novara, Italy; 2Nephrology, Dialysis and Kidney Transplantation Unit, University of Torino, Torino, Italy.

    Anti-HLA antibodies (abs) bind to kidney graft endothelial cells inducing complement-mediated injury and humoral rejection. Endothelial Progenitor Cells (EPC) are bone marrow-derived precursors able to…
  • 2016 American Transplant Congress

    A2 Kidneys into B Recipients: Is Postoperative Anti-A1 Titer Monitoring Useful?

    A. DeMers, R. Forbes, D. Moore, K. Smith, D. Shaffer.

    Kidney and Pancreas Transplantation, Vanderbilt University Medical Center, Nashville, TN.

    Background: Since the introduction of the new Kidney Allocation System in December 2014, our center implemented a protocol for transplanting A2 kidneys into B recipients…
  • 2016 American Transplant Congress

    In Their Own Words: Living Kidney Donors Who Develop Kidney Failure.

    L. Ross,1 C. Halverson,2 J. Wang,1 M. Poulson,3 J. Karlin,4 M. Crowley-Matoka.5

    1U Chicago, Chicago, IL; 2Anthropology, U Chicago, Chicago, IL; 3Georgetown U, Washington, DC; 4Family Medicine, UCSF, San Francisco, CA; 5Medical Humanities, Northwestern U, Chicago, IL.

    Background: Psychosocial data about living kidney donation have been collected for almost five decades. The results are almost uniformly positive, even in the early years…
  • 2016 American Transplant Congress

    Urine-Derived Cell Lines as a Novel Tool for Monitoring Allo-Reactivity in Kidney Transplant Patients.

    C. Thieme,1 B. Weist,1 M. Schmück,1 P. Reinke,1 N. Babel.1,2

    1Berlin-Brandenburg Center for Regenerative Therapies, University Medicine Berlin, Berlin, Germany; 2Medical Clinic I, Marien Hospital Herne, Ruhr-University Bochum, Herne, Germany.

    Reactivity of the immune system against donor antigens determines transplant-rejection after transplantation, and analyzing the alloimmune response has been shown to predict acute rejection in…
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