ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2016 American Transplant Congress

    Concomitant Proton Pump Inhibitor and Mycophenolate Mofetil Use in Renal Transplant Recipients.

    K. Patel,1 B. Stephany,2 J. Barnes,1 S. Bauer,1 M. Spinner.1

    1Department of Pharmacy, Cleveland Clinic, Cleveland, OH; 2Department of Nephrology and Hypertension, Cleveland Clinic, Cleveland, OH.

    Pharmacokinetic (PK) data show reduced mycophenolic acid levels in transplant recipients taking mycophenolate mofetil (MMF) and proton pump inhibitors (PPIs) concomitantly. MMF dosing is not…
  • 2016 American Transplant Congress

    Pulse Wave Velocity Amongst African-American Kidney Transplant Recipients Randomized to Once-Daily MeltDose Tacrolimus Tablets (Envarsus XR) vs. Traditional Twice-Daily Tacrolimus Capsules: Exploratory Results from a Phase III Trial.

    J. Trofe-Clark,1,2 R. Townsend,2 R. Neubauer,2 M. Lim,2 L. Callahan,3 R. Bloom.2

    1Pharmacy Services, Hospital of the University of Pennsylvania, Philadelphia, PA; 2Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA; 3Veloxis Pharmaceuticals, Edison, NJ.

    Cardiovascular (CV) death is a leading cause of death in kidney transplant recipients (KTR). Increased aortic arterial stiffness is strongly associated with the development of…
  • 2016 American Transplant Congress

    HLA Class II and BK Virus Reactivation in Renal Transplant Recipients.

    P. Shah,1 K. Anderson,2 M. Aubrey,2 C. Roark,2 B. Freed,2 A. Wiseman.1

    1Division of Renal Diseases and Hypertension, University of Colorado School of Medicine, Aurora, CO; 2Division of Immunology, University of Colorado School of Medicine, Aurora, CO.

    BK Viremia (BKV) and subsequent BK nephropathy are associated with renal graft loss. The Human Leukocyte Antigen (HLA) region has been implicated in susceptibility to…
  • 2016 American Transplant Congress

    Variation in Co-Medication Use According to Kidney Transplant Immunosuppressive Regimen: Application of Integrated Registry and Pharmacy Claims Data.

    K. Lentine,1 A. Naik,2 M. Schnitzler,1 D. Axelrod,3 J. Chen,1 D. Brennan,4 D. Segev,5 B. Kasiske,6 H. Randall,1 V. Dharnidharka.4

    1Saint Louis Univ, St. Louis; 2Univ Michigan, Detroit; 3Dartmouth Univ, Hanover; 4Washington Univ, St. Louis; 5Johns Hopkins Univ, Baltimore; 6Univ Minnesota, Minneapolis.

    Background: While modern immunosuppressive therapies (ISx) have substantially reduced acute rejection, ISx medications have many side effects, and transplant recipients must take an array of…
  • 2016 American Transplant Congress

    Sociodemographic and Comorbidity Differences Between Dialysis, Waitlisted and Transplant Patients in the UK: Findings from the ATTOM Study.

    D. Wu,1 M. Robb,2 C. Watson,3 R. Ravanan,4 J. Forsythe,1 A. Bradley,3 G. Oniscu.1

    1Royal Infirmary of Edinburgh, Edinburgh, United Kingdom; 2NHSBT, Bristol, United Kingdom; 3University of Cambridge, Cambridge, United Kingdom; 4Southmead Hospital, Bristol, United Kingdom.

    IntroductionAccess to Transplantation and Transplant Outcome Measures (ATTOM) is a prospective cohort study involving all 72 UK renal units, investigating factors affecting access to and…
  • 2016 American Transplant Congress

    The Presence of CMV-Specific T-Cells in CMV-Seronegative Kidney Transplant Recipients Predicts Outcome After Kidney Transplantation.

    T. Schachtner,1,2 M. Stein,2 P. Reinke.1,2

    1Nephrology and Internal Intensive Care, Charite Campus Virchow Clinic, Berlin, Germany; 2Berlin-Brandenburg Center for Regenerative Therapies, Charite Campus Virchow Clinic, Berlin, Germany.

    CMV-seronegative kidney transplant recipients (KTRs) from CMV-seropositive donors are at highly increased risk of primary CMV-infection with associated inferior outcomes after kidney transplantation. Presence of…
  • 2016 American Transplant Congress

    Graft Outcomes in Pediatric Kidney Transplants Are Better with Laparoscopic Donor Nephrectomy and High Volume Centers.

    J. Burg,1 D. Scott,1 K. Roayaie,1 E. Maynard,1 J. Barry,2 C. Enestvedt.1

    1Abdominal Organ Transplantation, OHSU, Portland, OR; 2Urology, OHSU, Portland, OR.

    Purpose Initial reports for pediatric kidney recipients suggested superior outcomes for open donor (ODN) compared to laparoscopic donor nephrectomy (LDN). Current outcomes based on donor…
  • 2016 American Transplant Congress

    Long-Term Outcomes of ATG versus IL-2 Receptor Antagonist in Low Risk Kidney Transplant Recipients: Donor Factors.

    F. Al Ammary, S. Bae, A. Massie, N. Desai, N. Dagher, E. Kraus, A. Wiseman, D. Segev.

    JHU, Baltimore; CU, Denver.

    Controversy exists regarding the optimal choice of induction therapy in low-risk kidney transplant (KT) recipients. Current guidelines specify induction choices in KT based on recipient…
  • 2016 American Transplant Congress

    Associations of Risk Factors and Kidney Retransplant Outcomes Vary Between Three Common Induction Agents: Results from the Analysis of Over Ten-Thousand Cases in Ten Years.

    A. Santos, X. Wen, M. Casey, S. Rehman, K. Womer.

    Medicine, University of Florida, Gainesville, FL.

    BACKGROUND: There is no published study comparing the significance of risk factors for graft outcomes associated with common induction regimens combined with tacrolimus and mycophenolate…
  • 2016 American Transplant Congress

    DAAs Rapidly Clear HCV Viremia in Recipients of HCV+ Donor Kidneys.

    D. Sawinski, R. Bloom, N. Patel.

    Renal Electrolyte and Hypertension Division, Hospital of the University of Pennsylvania, Philadelphia, PA.

    Purpose: Direct acting antivirals (DAAs) have revolutionized the treatment of hepatitis C (HCV) in both general and liver transplant populations. However, data in kidney transplant…
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