Articles tagged "Kidney transplantation"

2016 American Transplant Congress
Kidney Waitlist Management with Lean Six Sigma.
V. Arelin,¹ J. Schaefer,³ H. Haller,¹ I. Ackermann,² H. Schrem.²
¹Nephrology and Hypertension, Medical School Hanover, Hannover, Germany; ²Transplant and Viceral Surgery, Medical School Hanover, Hannover, Germany; ³Center for Information Technology, Medical School Hanover, Hannover, Germany.
BackgroundLean thinking is a bundle of concepts, methods and tools for organizing human activities in organizations. It attempts to eliminate the underlying unnecessary waste in…
2016 American Transplant Congress
Predictors of Patient Uncertainty Regarding Treatment Options Among End Stage Renal Disease Patients Evaluated for Kidney Transplantation.
L. McPherson,¹ M. Basu,¹ S. Pastan,¹ S. Mohan,² M. Wolf,³ J. Gander,¹ R. Patzer.¹
¹Emory University, Atlanta, GA; ²Columbia University, New York City, NY; ³Northwestern University, Chicago, IL.
Background: Although kidney transplantation (KTx) provides a significant survival benefit over long-term dialysis, many end stage renal disease (ESRD) patients are uncertain or conflicted about…
2016 American Transplant Congress
Evolution of Body Composition and Associations to Glucose Metabolism During the First Year After Kidney Transplantation.
M. von Düring,¹ A. Hartmann,^1,2 J. Bollerslev,^2,4 A. Åsberg,^1,3 K. Godang,⁴ I. Eide,¹ D. Dahle,¹ T. Jenssen.^1,5
¹Department of Transplantation Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway; ²Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway; ³School of Pharmacy, University of Oslo, Oslo, Norway; ⁴Department of Endocrinology, Oslo University Hospital, Rikshospitalet, Oslo, Norway; ⁵Metabolic and Renal Research Group, University of Tromsø, Tromsø, Norway.
Background. The evolution and association between body composition and glucose haemostasis after kidney transplantation has not been elucidated.Methods. We investigated 150 consecutive patients without suspected…
2016 American Transplant Congress
Long-Term Assessment of the Safety and Efficacy of IVIG and Rituximab-Based Desensitization (DES).
J. Choi, J. Kahwaji, A. Vo, S. Louie, A. Kang, A. Peng, R. Villicana, D. Puliyanda, I. Kim, S. Jordan.
Comprehensive Transplantation Center, Cedars-Sinai Medical Center, Los Angeles, CA.
Introduction: HLA sensitized patients constitute a growing number of ESRD patients with an immunologic barrier to successful transplantation. Desensitization (DES) therapies have emerged to address…
2016 American Transplant Congress
Impact of Early Calcineurin Inhibitor Withdrawal on Renal Function and Urinary Protein Excretion: 24 Month Analyses of the ELEVATE Study.
J. de Fijter,¹ H. Holdaas,¹ M. Seelen,¹ S. Sundar,¹ F. Bemelman,¹ P. Lopez,² J. Aguilar,² P. Bernhardt,² Z. Wang,³ J. Cruzado,¹ M. van der Giet.¹
¹ELEVATE study group, Leiden, Netherlands; ²Novartis, Basel, Switzerland; ³Novartis Pharmaceutical Corporation, East Hanover, NJ.
Background: Proteinuria is a biomarker which helps in predicting graft outcomes in kidney transplant recipients (KTxRs). The ELEVATE study was designed to determine whether an…
2016 American Transplant Congress
Effect of mTOR Inhibitors on the Risk of Cancer Development After Kidney Transplantation in Chinese Population.
C.-C. Kao,¹ J.-S. Liu,² M.-H. Lin,² F.-C. Chang,¹ Y.-C. Lin,¹ H.-H. Chen,¹ T.-W. Chen,¹ C.-C. Hsu,² M.-S. Wu.¹
¹Department of Internal Medicine, Taipei Medical University Hospital, Taipei, Taiwan; ²Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan.
Introduction The mTOR inhibitor is an immunosuppressive drug used in kidney transplantation. Whether the mTOR inhibitors is associated with reduced risk of cancer development in…
2016 American Transplant Congress
Smoking Exposure Among Kidney Allograft Recipients and Outcomes After Transplant.
H. Gillott,¹ S. Tahir,¹ F. Jackson-Spence,¹ F. Evison,² J. Nath,³ A. Sharif.³
¹Medical School, University of Birmingham, Birmingham, United Kingdom; ²Medical Informatics, Queen Elizabeth Hospital, Birmingham, United Kingdom; ³Nephrology and Transplantation, Queen Elizabeth Hospital, Birmingham, United Kingdom.
The causal effects of smoking on major comorbidity and mortality in the general population are well established. However, the influence of smoking exposure on kidney…
2016 American Transplant Congress
A 5-Year Multicenter Evaluation of Seasonal Influenza Infection in Transplant Recipients.
D. Kumar,¹ E. Cordero,⁴ E. Blumberg,² A. Limaye,⁵ M. Levi,⁷ L. Danziger-Isakov,⁹ J. Englund,⁸ S. Husain,¹ F. Silveira,¹⁰ G. Reid,⁶ T. Sharma,³ A. Humar.¹
¹UHN, Toronto, Canada; ²UPenn, Philadelphia; ³BCH, Boston; ⁴REIPI, Seville, Spain; ⁵UoWMC, Seattle; ⁶LUMC, Chicago; ⁷UCD, Denver; ⁸SCH, Seattle; ⁹CCHMC, Cincinnati; ¹⁰UPMC, Pittsburgh.
Background:Seasonal influenza infection may cause significant morbidity and mortality in transplant patients. However, there are limited prospective data on clinical presentations and determinants of outcomes.…
2016 American Transplant Congress
Comparison of C4d Deposition in Renal Biopsies with Luminex-Based C3d Single Antigen Bead (SAB) Detection.
R. Pelletier,¹ I. Balazs,² P. Adams,³ P. Steller,³ N. DiPaola,⁴ L. Rankin,³ A. Diez,⁵ M. Henry.¹
¹Surgery/Transplant, The Ohio State University Wexner Medical Center, Columbus, OH; ²Discovery Research, Immucor, Inc, Stamford, CT; ³Tissue Typing, The Ohio State University Wexner Medical Center, Columbus, OH; ⁴Methodist Hospital, Houston, TX; ⁵Nephrology, The Ohio State University Wexner Medical Center, Columbus, OH.
Recent interest in characterizing the complement-fixing ability of post-transplant donor specific alloantibodies (DSA) resulted in the enhancement of luminex solid phase alloantibody assays to determine…
2016 American Transplant Congress
Investigating Posttransplant Allo-Donor Specific CD57⁺ Cells in Patients with Alemtuzumab Induction and Belatacept-Based Regimen.
H. Xu, F. Feng, A. Kirk.
Department of Surgery, Duke University, Durham, NC.
Recent studies have showed correlation between CD4+CD57+PD1- cells and costimulation blockade resistant rejection (CoBRR) in patients treated with belatacept without depletional induction. We have recently…