- 2016 American Transplant Congress - In Their Own Words: Living Kidney Donors Who Develop Kidney Failure.Background: Psychosocial data about living kidney donation have been collected for almost five decades. The results are almost uniformly positive, even in the early years…
- 2016 American Transplant Congress - Urine-Derived Cell Lines as a Novel Tool for Monitoring Allo-Reactivity in Kidney Transplant Patients.Reactivity of the immune system against donor antigens determines transplant-rejection after transplantation, and analyzing the alloimmune response has been shown to predict acute rejection in…
- 2016 American Transplant Congress - Late Outcome Surrogate Score (LOSS) for Kidney Allograft Failure.- Comprehensive Transplant Center, Northwestern University, Chicago, IL. Background. Early outcomes following kidney transplant have steadily improved. Longer-term outcomes, while not the focus of regulatory oversight, are of vital importance. Clinical trials are…
- 2016 American Transplant Congress - Do Morbidly Obese Patients Have an Increased Risk of Infection Post-Kidney Transplant?- Medical University of South Carolina, Charleston, SC. Purpose: Obesity has been associated with significant morbidity in the kidney transplant population. The aim of this study was to assess the impact of obesity…
- 2016 American Transplant Congress - A Selective Biomarker in Blood Cells Identifies IFTA After Kidney Transplantation.Cellular and antibody-mediated rejection processes and also interstitial fibrosis/tubular atrophy (IFTA) lead to allograft dysfunction and loss. The search for accurate and specific diagnostic tools…
- 2016 American Transplant Congress - Attitudes Toward Living Kidney Transplantation Among Potential Transplant Candidates.- 1Yale U, New Haven; 2U Pennsylvania, Philadelphia; 3Northwestern U, Chicago. Background: Prior studies have shown that transplant candidates who are minorities and less educated are less willing to talk to others about living kidney donor…
- 2016 American Transplant Congress - A Comprehensive Biomarker Study to Compare Tacrolimus and Mycophenolic Acid versus Half-Dose Tacrolimus and Everolimus in De Novo Kidney Transplant Patients in the Novartis US92 Study.In this exploratory biomarker sub-study, a comprehensive combined targeted/ non-targeted metabolomics and targeted proteomics approach was used to assess potential differences between the everolimus+ low-dose…
- 2016 American Transplant Congress - Do We Need an Individually Tailored Immunosuppression Strategy for Living Donor Kidney Transplant Recipients with PreTransplant Donor Specific Antibodies? A Retrospective Analysis.Introduction:Pre-Transplant Microbead donor HLA specific antibody(DSA) positive but cell crossmatch negative transplants are considered to be at increased immunological risk. This study aimed to address…
- 2016 American Transplant Congress - Eversion Endarterectomy of the Deceased Donor Renal Artery to Prevent Kidney Discard.- Surgery, Wake Forest, Winston-Salem, NC. Deceased donor (DD) kidneys exhibiting severe atherosclerosis with hard ulcerative occlusive plaque extending into the renal artery (RA) may represent a contraindication to utilization. Limited…
- 2016 American Transplant Congress - Infections in De Novo Kidney Transplant Recipients Treated with the RANKL Inhibitor Denosumab: A Post-Hoc Analysis of the POSTOP Clinical Trial (NCT01377467).Background: A major cause of morbidity and mortality in kidney transplant recipients are infections. In this post-hoc analysis of the POSTOP study we assessed all…
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