Articles tagged "Kidney transplantation"

2016 American Transplant Congress
Post-Transplant Monitoring of Donor-Specific Anti-HLA Antibodies and Their Characteristics Improves Risk Stratification of Kidney Allograft Loss.
D. Viglietti,¹ A. Loupy,² C. Bentlejewski,³ C. Legendre,² D. Glotz,¹ A. Zeevi,³ C. Lefaucheur.¹
¹Saint-Louis Hospital, Paris, France; ²Necker Hospital, Paris, France; ³University of Pittsburgh Medical Center, Pittsburgh.
Circulating donor-specific anti-HLA antibodies (DSA) are associated with allograft failure in solid-organ transplantation. We investigated the pathogenic characteristics of DSA that may improve risk prediction…
2016 American Transplant Congress
Clinical Significance of Non-HLA Antibodies in the Development of Microcirculation Inflammation in Allograft Tissue After Kidney Transplantation.
J. Min,^1,3 H. Lee,^2,3 B. Chung,^1,3 E.-J. Oh,^2,3 C. Yang.^1,3
¹Division of Nephrology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea; ²Department of Laboratory Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea; ³Transplant Research Center, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
The aim of our study is to determine the clinical significance of pre-transplant non-HLA antibodies, mainly those targeting the angiotenin II type I receptor (AT1R)…
2016 American Transplant Congress
Comparison of Clinical Outcomes of Belatacept- and Tacrolimus-Based Immunosuppression in Renal Transplant Recipients.
X. Wen,¹ M. Casey,¹ A. Santos,¹ A. Hartzema,² K. Womer.¹
¹Department of Medicine, University of Florida, Gainesville, FL; ²Department of Pharmaceutical Outcomes and Policy, University of Florida, Gainesville, FL.
To examine the utilization and clinical outcomes of belatacept in the real clinical setting, a retrospective cohort study was conducted using SRTR data that compared…
2016 American Transplant Congress
Survival Advantage with Older Live Donor Compared to Standard Criteria Deceased Donor Kidney Transplantation in Older Recipients.
P. Abrams, M. Cooper, J. Verbesey, R. Ghasemian, M. Grafals, A. Gilbert, J. Moore, J. Fenton, C. Cannon, J. Rapisurra, B. Javaid.
MedStar Georgetown Transplant Institute, Georgetown University School of Medicine, Washington, DC.
Objective: Analyze post-transplant outcomes in older recipients of kidney transplants from older live donors compared to older recipients of standard criteria deceased donor kidney transplants.Methods:…
2016 American Transplant Congress
Clinical Significance of Isolated v1 Arteritis in Renal Transplantation.
D. Mikhail,^1,3 J. Wei,³ D. Kleinsteuber,² M. Gabril,^2,3 A. Sener,^1,3 M. Moussa,^2,3 P. Luke.^1,3
¹Department of Surgery, Division of Urology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada; ²Department of Pathology and Laboratory Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada; ³Undergraduate Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
INTRO: The presence of intimal arteritis (v) in renal transplant biopsies (Bx) establishes Grade II-III AVR (Acute Vascular Rejection) according to the Banff Classification. The…
2016 American Transplant Congress
Deceased Donor Urine C5a Predicts Donor and Recipient Acute Kidney Injury.
B. Schroppel,¹ P. Heeger,² I. Hall,³ M. Doshi,⁴ F. Weng,⁵ P. Reese,⁶ C. Parikh.³
¹University Hospital, Ulm, Germany; ²Mount Sinai School of Medicine, New York; ³Program of Applied Translational Research, Yale University School of Medicine, New Haven; ⁴Wayne State University, Detroit; ⁵Barnabas Health, Livingston; ⁶University of Pennsylvania, Philadelphia.
Anti-complement therapies are currently being tested in human kidney transplantation to prevent DGF. In this large prospective, cohort study of 469 deceased organ donors, we…
2016 American Transplant Congress
High KDPI Kidneys (>85%) Do Not Adversely Affect HRQOL After Kidney Transplantation.
R. Forbes, I. Feurer, D. LaNeve, C. Gamble, D. Shaffer.
Vanderbilt University Medical Center, Nashville, TN.
Background. Since December 2014, deceased donor kidneys are allocated based on a kidney donor profile index (KDPI) by four sequences, A thru D. Estimated kidney…
2016 American Transplant Congress
KDPI Outcomes and Discard Rates – The Contradiction of the U.S. and European Approach.
L. Lehner, A. Kleinsteuber, F. Halleck, D. Khadzhynov, M. Duerr, K. Budde, O. Staeck.
Dept. of Nephrology CCM, Charite Berlin, Berlin, Germany.
Introduction: Only a few data exist on the KDPI in European patients (pts). We evaluated the influence of donor factors assessed by the KDPI on…
2016 American Transplant Congress
Hospital Readmissions Following Incompatible Kidney Transplantation: A Multi-Center Study.
B. Orandi, E. King, X. Luo, S. Bae, B. Lonze, R. Montgomery, D. Segev.
Johns Hopkins, Baltimore.
Desensitization and incompatible live donor kidney transplantation (ILDKT) has improved survival vs. forgoing transplant or waiting for a compatible one. It is unknown if increased…
2016 American Transplant Congress
Young, Caucasian, Better Educated and Less Socially Deprived Patients Are More Likely to Be Transplanted with a Living Donor Kidney in the UK.
D. Wu,¹ M. Robb,² C. Watson,³ R. Ravanan,⁴ J. Forsythe,¹ W. Metcalfe,¹ C. Dudley,⁴ C. Bradley,⁵ H. Draper,⁶ A. Bradley,³ G. Oniscu.¹
¹Royal Infirmary of Edinburgh, Edinburgh, United Kingdom; ²NHSBT, Bristol, United Kingdom; ³University of Cambridge, Cambridge, United Kingdom; ⁴Southmead Hospital, Bristol, United Kingdom; ⁵University of London, London, United Kingdom; ⁶University of Birmingham, Birmingham, United Kingdom.
IntroductionLiving donor kidney transplantation (LDKT) has significant benefits over deceased donor kidney transplantation (DDKT) in terms of improved survival and timely access to transplant. There…