2016 American Transplant Congress
Conversion to Belatacept as Rescue Therapy in Kidney Transplant Recipients with Severe Graft Dysfunction.
Belatacept is a fusion protein that prevents T cell co-stimulation via the CD28 receptor. If used as first-line therapy, immunosuppression with Belatacept is associated with…2016 American Transplant Congress
Donor-Specific Antibodies in a Single-Center Pediatric Kidney Transplant Population – Incidence and Risk Factors.
In mid-2015, we implemented donor-specific antibody (DSA) monitoring in our pediatric kidney transplant recipient (pKTR) population as recommended (Transplantation 2013;95:19-). We now cross-sectionally analyzed our…2016 American Transplant Congress
Incidence of Polyoma Virus Associated Nephropathy in a Single Transplant Center Employing a Reduction of Immunosuppression at a Lower Threshold of BK Viremia.
Internal Medicine, Infectious Diseases, Yale University, New Haven, CT.
BackgroundPolyoma virus associated nephropathy (PyVAN) caused by BK virus (BKV) is a major complication occurring in 1-10% of renal transplant recipients. Screening and reduction of…2016 American Transplant Congress
Risk Factors for Single and Recurrent Symptomatic Urinary Tract Infections within the First Year After Kidney Transplantation.
Henry Ford Hospital, Detroit, MI.
Urinary Tract Infection (UTI) is the most common infection after kidney transplantation (KT). However studies have been incongruent regarding risk factors associated with incidence and…2016 American Transplant Congress
Clinical Significance of Mycophenolic Acid Therapeutic Drug Monitoring in Kidney Transplant Recipients.
Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea.
Background: Mycophenolic acid (MPA) is a widely used immunosuppressant to prevent acute rejection in kidney transplant recipients (KTRs). However, clinical significance of MPA therapeutic drug…2016 American Transplant Congress
Kidney Transplant Recipient Adherence Measured by Proportion of Days Covered Is Associated with Late Biopsy Proven Acute Rejection.
While medication non-adherence is a known risk factor for late “biopsy proven acute rejection (BPAR),” the Pharmacy Quality Alliance definition of “proportion of days covered…2016 American Transplant Congress
Potential Applications of Viral miRNA Assays in the Management of Transplant Patients with Polyomavirus BK Infection.
Background: BKV encodes two miRNAs from a single precursor: BKV-miR-B1-5p & BKV-JCV-miR-BJ1-3p. These viral miRNAs direct cleavage of large T antigen mRNAs, downregulate viral T…2016 American Transplant Congress
P-Glycoprotein Function: Association with Race, Gender and Tacrolimus Pharmacokinetics.
Background: Long term allograft survival remains poorer in African American(AA) renal transplant recipients(RTR) compared to Caucasians(C) and may be due to racial differences in calcineurin…2016 American Transplant Congress
Using Predictive Modeling to Manage Cardiovascular Risk and Improve Kidney Transplant Outcomes.
Objective: We aimed to improve post-kidney transplant (tx) outcomes through predictive analytics and natural language processing (NLP) integrated into the electronic health record (EHR). The…2016 American Transplant Congress
CMV Immune Monitoring with a CMV ELISPOT Test in Kidney Transplant Patients.
Department of Renal Medicine, Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom.
Cytomegalovirus (CMV) is an important opportunistic infection in kidney transplant recipients (KTR). Whilst pre-emptive or prophylactic anti-viral regime reduce CMV complications, drug toxicity and resistance…
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