ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2016 American Transplant Congress

    Urine Cell-Free Supernatant Metabolites Diagnostic of Antibody Mediated Rejection in Kidney Allografts.

    M. Alkadi,1 J. Lee,1 D. Dadhania,1 T. Muthukumar,1 C. Snopkowski,1 C. Li,1 S. Salvatore,1 S. Seshan,1 K. Suhre,2 M. Suthanthiran.1

    1Weill Cornell Medicine, NY; 2Weill Cornell Medical College-Qatar, Doha, Qatar.

    Introduction:Urine cell-free supernatant metabolite profiles provide a unique opportunity to interrogate intra-graft processes and have distinguished acute cellular rejection from no rejection in the Clinical…
  • 2016 American Transplant Congress

    Anti-IL6R Therapy (Tocilizumab) Improves Long-Term Patient & Graft Survival in Patients with Chronic Antibody-Mediated Rejection and Transplant Glomerulopathy.

    J. Choi, A. Vo, M. Haas, D. Puliyanda, S. Louie, A. Peng, J. Kahwaji, R. Villicana, I. Kim, J. Mirocha, S. Jordan.

    Comprehensive Transplantation Center, Cedars-Sinai Medical Center, Los Angeles, CA.

    Introduction:Extending the functionality of renal allografts is an essential goal of transplant medicine. HS patients (pts) are at increased risk for chronic ABMR (CABMR) due…
  • 2016 American Transplant Congress

    Black Ethnicity as a Risk Factor for Poor Kidney Allograft Outcomes Post-Transplantation.

    S. Tahir,1 F. Jackson-Spence,1 H. Gillott,1 F. Everson,2 J. Nath,2 A. Sharif.2

    1University of Birmingham, Birmingham, United Kingdom; 2Queen Elizabeth Hospital, Birmingham, United Kingdom.

    Introduction: Registry studies, largely from the United States, have consistently demonstrated inferior outcomes for black patients undergoing renal transplant. A recent Canadian publication has challenged…
  • 2016 American Transplant Congress

    Impact of Delayed Graft Function Varies by Demographic and Clinical Characteristics in Deceased Donor Kidney Transplantation.

    C. Liao, A. Massie, S. Bae, A. Muzaale, D. Segev.

    JHU, Baltimore.

    Single-center studies have suggested potential differences in the impact of DGF by recipients' biological susceptibility, quality of allograft, and immune compatibility. The goal of this…
  • 2016 American Transplant Congress

    Epitope Load Is Predictive of De Novo Donor Specific Antibodies Occurrence in Renal Transplant Recipients After Conversion from Cyclosporine to Everolimus.

    R. Snanoudj,1 C. Suberbielle,2 N. Kamar,3 E. Cassuto,4 S. Caillard,5 J.-L. Taupin,2 D. Anglicheau,1 C. Legendre,1 A. Hertig,6 E. Rondeau.6

    1Necker Hospital, Paris, France; 2Saint-Louis Hospital, Paris, France; 3Rangueil Hospital, Toulouse, France; 4Pasteur Hospital, Nice, France; 5CHRU, Strasbourg, France; 6Tenon Hospital, Paris, France.

    IntroductionThe degree of HLA compatibility between donor and recipient is an important risk factor of developing de novo DSA, but misjudged by the number of…
  • 2016 American Transplant Congress

    MicroRNAs in Urinary Sediments as Non-Invasive Tool to Detect Acute Rejection After Kidney Transplantation.

    E. Gielis,1,2 J. Anholts,2 H. de Fijter,3 I. Bajema,4 F. Claas,2 M. Eikmans.2

    1Laboratory of Experimental Medicine and Pediatrics, University of Antwerp, Antwerp, Belgium; 2Immunohematology, LUMC, Leiden, Netherlands; 3Nephrology, LUMC, Leiden, Netherlands; 4Pathology, LUMC, Leiden, Netherlands.

    MicroRNAs in urine are suitable targets for non-invasive detection of acute rejection (AR), since they represent relatively stable analytes. Indeed, we found that PCR signals…
  • 2016 American Transplant Congress

    Characteristics of Compatible Pair Participants in Living Donor Kidney Transplant Exchanges.

    F. Weng, T. Grogan, A. Patel, S. Mulgaonkar, M. Morgievich.

    Renal & Pancreas Transplant Division, Saint Barnabas Medical Center, Livingston, NJ.

    Introduction: Compatible pairs of living kidney donors and their intended recipients are being increasingly entered into living donor kidney transplant (LDKT) exchanges. The characteristics of…
  • 2016 American Transplant Congress

    Pulmonary Hypertension in Renal Transplant Candidates: A Systematic Review and Meta-Analysis of the Available Evidence.

    A. Moza,1 A. Khan,2 R. Prashar,3 S. Khan,1 S. Khouri,1 S. Vetteth,1 D. Malhotra,1 M. Rees,1 G. Moukarbel,1 J. Ortiz.1

    1Cardiovascular Medicine, University of Toledo Medical Center, Toledo, OH; 2Cardiovascular Medicine, University of Louisville, Louisville, KY; 3Nephrology and Transplantation, Henry Ford Medical Center, Detroit, MI.

    Background: Pulmonary hypertension (PHT) is common in patients with end stage renal disease (ESRD). Moderate to severe PHT is a strong independent predictor of mortality…
  • 2016 American Transplant Congress

    Immunologic Basis for Immunocloaking.

    L. Brasile,1 K. Kizjakina,1 N. Henry,1 B. Stubenitsky.2

    1BREONICS Inc., Watervliet, NY; 2Plastic Surgery, University of Utrecht, Utrecht, Netherlands.

    A novel organ-specific immunomodifying therapy referred to as immunocloaking (IC) provides protection from early allograft rejection without immunosuppressive drugs. The IC binds to the surfaces…
  • 2016 American Transplant Congress

    NEAD Chains Do Not Disadvantage Blood Type O, Black, or Highly Sensitized Patients.

    M. Rees,1 J. Roberts,2 K. Lentine,3 A. Roth,4 A. Leichtman,5 H. Xiao,3 S. Rafizadeh,1 E. Neidich,2 M. Melcher.4

    1UT, Toledo; 2UCSF, SF; 3SLU, St Louis; 4Stanford, Palo Alto; 5Arbor Res, Ann Arbor.

    Introduction: NEAD chains raised concern that wait-listed blood type (BT) O patients and racial minorities would be disadvantaged by allocation of a non-directed donor (NDD)…
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