Articles tagged "Kidney transplantation"

2016 American Transplant Congress
Predictive Model of Delayed Graft Function in Machine Perfused Kidney Transplantation: Model Validation Using Decision Curve Analysis.
K. Ravindra,¹ S. Sanoff,¹ D. Vikraman,¹ U. Patel,¹ M. Ellis,¹ E. Squires,² D. Sudan,¹ W. Irish.¹
¹Surgery, Duke University, Durham, NC; ²Half Moon Bay, Raleigh.
Introduction: Predictive model for delayed graft function (DGF) was developed (Am J Transpl 2010; 10: 2279–86)excluding organs that were machine perfused (MP). Currently, approximately 50%…
2016 American Transplant Congress
Preimplantation and Post-Transplant Serial Biopsies of Standard and Extended Criteria Donor Kidneys: Intragraft Molecular Profiles and Effect of Different Immunosuppressive Protocols.
C. Mazeti,¹ H. Caldas,¹ I. Fernandes-Charpiot,² M. Baptista,² M. Abbud-Filho.^1,2,3
¹Laboratory of Immunology and Experimental Transplantation, Medical School, Sao Jose do Rio Preto, SP, Brazil; ²Department of Medicine/Nephrology, Medical School, Sao Jose do Rio Preto, SP, Brazil; ³Urology and Nephrology Institute, Urology and Nephrology Institute, Sao Jose do Rio Preto, SP, Brazil.
Background: Use of extended criteria donor kidneys (ECD) carries the fear of to transplant of inferior quality and therefore of high discard rate. Clinical tools…
2016 American Transplant Congress
Early Hospital Readmission After Kidney Transplantation: Seasonality, Causes and Prognosis.
M. Tavares, M. Cristelli, L. Viana, M. de Paula, H. Silva Junior, J. Medina Pestana.
Nephrology Division, Hospital do Rim Foundation, Universidade Federal de Sao Paulo, Sao Paulo, Brazil.
Background: In the general population, 30-day hospital readmission rate is a well-accepted quality metric and a predictor of mortality. A growing body of data suggests…
2016 American Transplant Congress
Risk Factors for the Development of CMV Viremia in a Cohort of Morbidly Obese Kidney Transplant Recipients Under Low Dose Valganciclovir Prophylaxis.
J. Thielke,¹ N. Jasiak,¹ N. Hilal,¹ S. Salah,¹ E. Benedetti,² P. West-Thielke.²
¹Pharmacy Practice, Univ of IL-Chicago Medical Center, Chicago, IL; ²Dept of Surgery, Univ of IL-Chicago Medical Center, Chicago, IL.
Background: The rate of Cytomegalovirus infections in kidney transplant recipients drastically diminished with the advent of oral ganciclovir and subsequently valganciclovir. However it continues to…
2016 American Transplant Congress
Enhanced Natural Killer Responsiveness Is a Potent Cytotoxic Mechanism Associating to Kidney Allograft Dysfunction and Pathogenic Effects of Donor-Specific Antibodies (DSA).
P. Paul,^1,2 T. Legris,³ C. Picard,⁴ D. Todorova,^1,2 L. Lyonnet,¹ L. Daniel,⁵ B. Dussol,^3,6 V. Moal,³ H. Vacher Coponat,³ Y. Berland,³ F. Dignat-George,^1,2 S. Burtey.^2,3
¹Hematology, Assistance Publique Hopitaux Marseille, Marseille, France; ²UMR-1076, VRCM, Aix Marseille University, INSERM, Marseille, France; ³Nephrology Dialysis Renal Transplantation Center, Assistance Publique Hopitaux Marseille, Marseille, France; ⁴Immunogenetics, Etablissement Français du Sang, Marseille, France; ⁵Anatomy, Pathology, Neuropathology, Assistance Publique Hopitaux Marseille, Marseille, France; ⁶Center for Clinical Investigation, Assistance Publique Hopitaux Marseille, Marseille, France.
While antibody mediated rejection (ABMR) is a major cause of kidney transplant loss, the role of Natural Killer cells (NK) as immune effectors of complement-independent…
2016 American Transplant Congress
Chemokine Receptor CXCR4 Antagonist, a Novel Pathway to Prevent Chronic Allograft Nephropathy.
Y. Xu, Q. Zhang, X. Hu.
Department of Urology, Beijing Chaoyang Hospital, Beijing, China.
BackgroundChronic allograft nephropathy (CAN) remains a major problem for long term graft survival and different pathways participate in its development. CXC chemokine receptor 4 (CXCR4)…
2016 American Transplant Congress
Kidney Transplants from Anuric Deceased Donors on Renal Replacement Therapy.
W. Bry, J. Bellingham, S. Katznelson, P. Patel, K. Ueda, H. Mahanty, N. Neidlinger, A. Hassoun, V. Peddi.
Transplantation, California Pacific Medical Center, San Francisco, CA.
Transplantation of deceased donor kidneys with Acute Kidney Injury (AKI) has become a generally well accepted practice with excellent results documented in the literature. The…
2016 American Transplant Congress
Belatacept Conversion in Adult Kidney Transplant Recipients for Cause: A Single Center Observational Cohort.
M. Savic,¹ M. Cruz,² A. Rossi,¹ J. Vella.¹
¹Maine Transplant Program, Maine Medical Center, Portland, ME; ²University of Connecticut, Storrs, CT.
Background: Calcineurin inhibition (CNI) is the single most effective strategy to prevent allograft rejection however tolerability is limited by toxicity. To date, alternate strategies have…
2016 American Transplant Congress
A Visualization Software Platform for Managing a Kidney Paired-Donation Program.
M. Bray,¹ W. Wang,¹ M. Rees,² P. Song,¹ A. Leichtman,³ V. Ashby,¹ J. Kalbfleisch.¹
¹University of Michigan, Ann Arbor, MI; ²University of Toledo, Toledo, OH; ³Arbor Research, Ann Arbor, MI.
A kidney paired-donation (KPD) program's aim is typically to maximize the number of transplants achieved via cycles among incompatible donor-candidate pairs, as well as chains…
2016 American Transplant Congress
Factors Associated with Response to Plasmapheresis in Patients with Recurrent FSGS.
J. Shoji,¹ V. Tatapudi,² Z. Laszik,¹ A. Jones,³ J. Wolf,⁴ D. Adey,¹ F. Vincenti.¹
¹Department of Medicine, Division of Nephrology, University of California-San Francisco, California, CA; ²Department of Medicine, Division of Nephrology, New York University, New York, NY; ³Department of Sociology, George Washington University, Washington, DC; ⁴Transplant Surgery, Piedmont Transplant Institute, Atlanta, GA.
Background:Idiopathic focal segmental glomerulosclerosis (FSGS) is one of the primary glomerular diseases that commonly recurs in renal allograft and is known to be associated with…