Articles tagged "Kidney transplantation"

2016 American Transplant Congress
The Effect of Tocilizmab Treatment (TCZ-Rx) on IgG Subclasses in HLA-sensitized (HS) Kidney Transplant Patients Treated with TCZ.
B.-H. Shin, S. Ge, J. Choi, J. Kahwaji, A. Vo, A. Petrosyan, S. Jordan, M. Toyoda.
Transplant Immunology Laboratory and Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.
Background: Antibody-mediated rejection (ABMR) is a major obstacle for successful transplant in HS patients. TCZ has anti-B cell and anti-inflammatory properties. We have reported its…
2016 American Transplant Congress
Evaluation of Dose Dependent Rabbit Anti-Thymocyte Globulin Induction in Risk-Stratified Kidney Transplant Recipients.
I. Gutman, M. Misel, D. McKay, A. Hemming, J. Kerr, K. Mekeel.
UC San Diego Health System, San Diego, CA.
Background: Rabbit anti-thymocyte globulin (rATG) is a depleting polyclonal antibody often used for induction following kidney transplantation to help prevent acute rejection. The optimal dosage…
2016 American Transplant Congress
The Environmental Impact of Dialysis vs Transplantation.
M. Grafals,¹ R. Sanchez.²
¹Medstar Georgetown Transplant Institute, Georgetown University, Washington, DC; ²Environmental Health, Harvard University, Boston, MA.
Introduction: Hemodialysis has a large environmental impact because it uses large volumes of water, medical supplies and energy. A patient undergoing weekly dialysis treatment (three…
2016 American Transplant Congress
Robotic-Assisted Laparoscopic Donor Nephrectomy with Transvaginal Extraction of the Kidney.
C. Champy,¹ L. Salomon,¹ I. Cholley,¹ A. Hoznek,¹ R. Yiou,¹ D. Vordos,¹ P. Grimbert,² P. Lang,² A. De La Taille.¹
¹Urology Department - INSERM U955, Henri Mondor, Créteil, France; ²Nephrology Department, Henri Mondor, Créteil, France.
Minimally invasive surgery aims to the reduction of complications, pain and scars. Thus, vaginal extraction of the donor's kidney has been reported as an option…
2016 American Transplant Congress
Predicting Delayed Kidney Graft Function with Gene Expression in Preimplantation Biopsies.
T. Mourão,^1,3 K. Mine,¹ E. Campos,^1,3 J. Medina-Pestana,^2,3 H. Tedesco-Silva,² M. Gerbase-De Lima.
¹Immunogenetics Institute, Associação Fundo de Incentivo à Pesquisa - AFIP, São Paulo, SP, Brazil; ²Hospital do Rim e Hipertensão, Fundação Oswaldo Ramos, São Paulo, SP, Brazil; ³UNIFESP, São Paulo, SP, Brazil.
Aiming to further the investigation of markers in pre-implantation biopsies (PIB) for the prediction of delayed graft function (DGF), we analyzed, in a different cohort…
2016 American Transplant Congress
Preimplant Donor Histology Does Not Improve Discrimination of 5 Year Kidney Allograft Outcomes.
C. Traynor,¹ T. Dorman,² D. de Freitus,² P. Conlon,² C. O'Seaghdha.²
¹Nephrology, Duke University Hospital, Durham, NC; ²Nephrology, Beaumont Hospital, Dublin, Ireland.
Kidney transplantation remains the best treatment option for End-Stage Kidney Disease (ESKD) and the most cost efficient method of renal replacement therapy. However, there is…
2016 American Transplant Congress
Resource Utilization and Cost Analysis of Early Hospital Readmissions Following Kidney Transplantation.
M. Au, O. Famure, Y. Li, J. Kim.
Multi-Organ Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada.
Background: Early hospital readmissions (EHRs) following kidney transplant are associated with poor transplant outcomes and a greater burden on the healthcare system. However, the financial…
2016 American Transplant Congress
Quantiferon-CMV Test, CMV-Specific ELISPOT and CMV-Dextramer Assays in Assessing the Risk of CMV Infection in Seropositive Kidney Transplant Recipients.
H. Lee,¹ K. Park,² J. Ryu,² J. Yu,³ B. Chung,³ C. Yang,³ E.-J. Oh.¹
¹Department of Laboratory Medicine, The Catholic University of Korea, Seoul, Korea; ²Department of Biomedical Science, Graduate School, The Catholic University of Korea, Seoul, Korea; ³Division of Nephrology, Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.
Human cytomegalovirus (CMV) infection is one of the primary opportunistic pathogens and is a leading cause of morbidity and mortality in kidney transplant recipients. Assessing…
2016 American Transplant Congress
Digital Kidney Biopsy Evaluation: Quantification of Macrophage Prevalence in a Cross Sectional Study.
J. Schmitz,¹ A. Khalifa,¹ H. Haller,² H. Kreipe,¹ F. Feuerhake,¹ J. Bräsen.¹
¹Institute of Pathology, Hannover Medical School, Hannover, Germany; ²Department of Nephrology and Hypertension, Hannover Medical School, Hannover, Germany.
Standardized markers based on quantitative and qualitative evaluation of immune cell mass and localization in kidney biopsies may help in diagnosis and prognosis in transplantation…
2016 American Transplant Congress
Complement Receptor C5aR2 Deletion in Kidney Transplantation in Mice Attenuates Renal Damage.
A. Thorenz,¹ R. Chen,¹ K. Hueper,² B. Hensen,² C. Klemann,³ M. Meier,⁴ A. Klos,⁵ F. Gueler.¹
¹Nephrology, Medical School, Hannover, Germany; ²Radiology, Medical School, Hannover, Germany; ³Paediatric Surgery, Medical School, Hannover, Germany; ⁴Central Animal Facility, Medical School, Hannover, Germany; ⁵Microbiology, Medical School, Hannover, Germany.
ObjectiveThe complement receptors C5aR1 and C5aR2 serve distinct roles in immune regulation. In kidney transplantation the early post-implant ischemia reperfusion injury (IRI) causes rapid complement…