2022 American Transplant Congress
Long-Term Clinical Outcomes in ABO Incompatible Kidney Transplantation in Patients with High Baseline Anti-A/B Antibody Titer
*Purpose: ABO incompatible (ABOi) kidney transplantation (KT) has been considered to overcome donor shortage. We investigated the long-term clinical outcomes in ABOi KT in patients…2022 American Transplant Congress
Novel Biopsy-Based Clinical Phenotype Clustering to Predict Kidney Transplant Outcomes
*Purpose: The purpose of this study was to define novel clinical phenotypes based on biopsy results to enhance biomarker discovery.*Methods: Retrospective analysis of kidney biopsy…2022 American Transplant Congress
Genotype and Phenotype Analysis and the Transplantation Strategy in Children with Uremia Caused by Nephronophthisis
Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
*Purpose: Nephronophthisis- related ciliopathies(NPHP- RC), as an important cause of children's end-stage renal disease(ESRD), has strong genotype and phenotype heterogeneity, and the transplantation strategy of…2022 American Transplant Congress
The Impact of Food Insecurity on Pediatric Kidney Transplant Outcomes
Pediatric Nephrology, Lurie Children's Hospital, Chicago, IL
*Purpose: We previously demonstrated a prevalence of food insecurity (FI) of 26.7% at our institution, in a pilot study of 45 pediatric kidney transplant (pedsKTx)…2022 American Transplant Congress
30-day Readmissions After Atrial Fibrillation Associated Hospitalizations in Kidney Transplant Recipients
University of Wisconsin Madison, Madison, WI
*Purpose: Atrial fibrillation (AF) associated hospitalizations are associated with a substantial 30-day readmission burden. There are few data on incidence and causes of 30-day readmissions…2022 American Transplant Congress
Serological Response To Three, Four And Five Doses Of Sars-cov-2 Vaccine In Kidney Transplant Recipients
*Purpose: Mortality from COVID-19 among kidney transplant recipients (KTR) is unacceptably high, and their response to up to three vaccinations against SARS-CoV-2 is strongly impaired.…2022 American Transplant Congress
Low-Dose Aspirin is Effective in Preventing Transplant Renal Artery Stenosis: A Prospective Randomized Controlled Trial
Henan Provincial People's Hospital, Zhengzhou, Henan Province, China
*Purpose: Transplant renal artery stenosis (TRAS), the most common post-transplant vascular complication, leads to resistant hypertension, renal impairment, and even graft loss. No effective prophylactic…2022 American Transplant Congress
Autencoder, a Novel Computational Tool to Score T Cell Clones Demonstrates Biopsy T Cell Clones Are Not Represented in the Peripheral Blood
Washington University, St Louis, MO
*Purpose: Antibody-mediated rejection (AMR) remains one of the major causes of allograft failure and our understanding of this disease process is poor. The generation and…2022 American Transplant Congress
Three-Way Comparison of Central DSA, %dd-cf DNA, and Molecular Biopsy Findings in the Trifecta Study
*Purpose: Trifecta (ClinicalTrials.gov #NCT04239703) is a prospective, IRB-approved, consented study of the relationships among three central tests in kidney transplant indication biopsies: molecular biopsy diagnoses…2022 American Transplant Congress
A New Algorithm Combining Donor Derived Cell-Free DNA Fraction and Quantity to Detect Kidney Transplant Rejection Using Molecular Diagnoses and Histology
1Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, 2Natera, Inc., Austin, TX
*Purpose: Donor derived cell-free DNA (dd-cfDNA) has been shown to be associated with allograft rejection, both histological and molecular (JASN, in press). Clinically available dd-cfDNA…
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