Articles tagged "Kidney transplantation"

2016 American Transplant Congress
Influence of Lipid Levels on Cardiovascular Events After Early Conversion from Calcineurin Inhibitor to Everolimus: 24 M Analysis of the ELEVATE Study.
M. van der Giet,¹ J. de Fijter,¹ F. Oppenheimer,¹ L. Toselli,¹ G. Russ,¹ P. Lopez,² J. Aguilar,² P. Bernhardt,² Z. Wang,³ J. Cruzado,¹ H. Holdaas.¹
¹ELEVATE study group, Berlin, Germany; ²Novartis pharma AG, Basel, Switzerland; ³Novartis Pharmaceutical Corporation, East Hanover, NJ.
Background: Immunosuppressive therapies are probably the most important cause of hyperlipidemia post-renal transplantation (RTx). Lipid abnormalities represent important biomarkers for cardiovascular (CV) risk. Here, we…
2016 American Transplant Congress
How Did the New Kidney and Pancreas Allocation Systems Effect Pancreas Utilization in the First Six-Months?
R. Carrico,¹ J. Fridell,² J. Odorico,³ Z. Stewart.⁴
¹UNOS, Richmond, VA; ²Indiana Univ School of Medicine, Indianapolis, IN; ³Univ of Wisconsin Hospital and Clinics, Madison, WI; ⁴Univ of Iowa Hospital and Clinics, Iowa City, IA.
Background: In 2010 a new pancreas allocation system (PAS) was approved by the OPTN and implemented in October 2014, shortly preceding the new kidney allocation…
2016 American Transplant Congress
Return on Investment for Financial Assistance for Living Kidney Donors in the United States.
A. Mathur,¹ J. Xing,² D. Dickinson,² P. Warren,³ K. Gifford,³ B. Hong,⁴ A. Ojo,⁵ R. Merion.^2,5
¹Mayo Clinic, Phoenix; ²Arbor Research Collaborative for Health, Ann Arbor; ³ASTS, Arlington; ⁴Washington University in St. Louis, St. Louis; ⁵University of Michigan, Ann Arbor.
Background: Federal financial support through the National Living Donor Assistance Center (NLDAC) assists potential living donors who have prohibitive out-of-pocket expenses. We calculated the return…
2016 American Transplant Congress
Induction Therapy with Rabbit Antithymocyte Globulin (rATG, Thymoglobulin^®) vs Basiliximab After Kidney Transplantation: A Health Economic Analysis from a German Perspective.
L. Cremaschi,¹ R. Thissen,² T. Benzing,² M. Wiesener,³ N. Zink,³ T. Paivanas,⁴ J. Reitan,⁴ M. Gallagher,⁵ F. Thaiss.¹
¹Univ. Hospital Eppendorf UKE, Hamburg, Germany; ²Univ. Hospital Cologne, Colgone, Germany; ³Univ. Hospital Erlangen-Nürnberg, Erlangen, Germany; ⁴RJM Group, LLC, Washington, DC; ⁵Sanofi-Aventis US, Cambridge, MS.
Study objective. A health economic analysis was undertaken to quantify the economic consequences of acute rejection and serious adverse events in patients receiving induction with…
2016 American Transplant Congress
Initial Experience Treating Hepatitis C Positive Kidney Transplant Recipients with Non-Interferon-Containing Regimens: Successes and Challenges.
M. Aull, A. Watkins, J. Kim, K. Rhee, D. Dadhania, J. Lee, S. Kapur.
Weill Cornell Medical College, New York, NY.
Historically, treatment of hepatitis C virus (HCV) infection with interferon-based regimens after kidney transplantation has been associated with risk of rejection & graft loss. Direct…
2016 American Transplant Congress
Post-Transplant Monitoring of Donor-Specific Anti-HLA Antibodies and Their Characteristics Improves Risk Stratification of Kidney Allograft Loss.
D. Viglietti,¹ A. Loupy,² C. Bentlejewski,³ C. Legendre,² D. Glotz,¹ A. Zeevi,³ C. Lefaucheur.¹
¹Saint-Louis Hospital, Paris, France; ²Necker Hospital, Paris, France; ³University of Pittsburgh Medical Center, Pittsburgh.
Circulating donor-specific anti-HLA antibodies (DSA) are associated with allograft failure in solid-organ transplantation. We investigated the pathogenic characteristics of DSA that may improve risk prediction…
2016 American Transplant Congress
Clinical Significance of Non-HLA Antibodies in the Development of Microcirculation Inflammation in Allograft Tissue After Kidney Transplantation.
J. Min,^1,3 H. Lee,^2,3 B. Chung,^1,3 E.-J. Oh,^2,3 C. Yang.^1,3
¹Division of Nephrology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea; ²Department of Laboratory Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea; ³Transplant Research Center, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
The aim of our study is to determine the clinical significance of pre-transplant non-HLA antibodies, mainly those targeting the angiotenin II type I receptor (AT1R)…
2016 American Transplant Congress
Comparison of Clinical Outcomes of Belatacept- and Tacrolimus-Based Immunosuppression in Renal Transplant Recipients.
X. Wen,¹ M. Casey,¹ A. Santos,¹ A. Hartzema,² K. Womer.¹
¹Department of Medicine, University of Florida, Gainesville, FL; ²Department of Pharmaceutical Outcomes and Policy, University of Florida, Gainesville, FL.
To examine the utilization and clinical outcomes of belatacept in the real clinical setting, a retrospective cohort study was conducted using SRTR data that compared…
2016 American Transplant Congress
Survival Advantage with Older Live Donor Compared to Standard Criteria Deceased Donor Kidney Transplantation in Older Recipients.
P. Abrams, M. Cooper, J. Verbesey, R. Ghasemian, M. Grafals, A. Gilbert, J. Moore, J. Fenton, C. Cannon, J. Rapisurra, B. Javaid.
MedStar Georgetown Transplant Institute, Georgetown University School of Medicine, Washington, DC.
Objective: Analyze post-transplant outcomes in older recipients of kidney transplants from older live donors compared to older recipients of standard criteria deceased donor kidney transplants.Methods:…
2016 American Transplant Congress
Clinical Significance of Isolated v1 Arteritis in Renal Transplantation.
D. Mikhail,^1,3 J. Wei,³ D. Kleinsteuber,² M. Gabril,^2,3 A. Sener,^1,3 M. Moussa,^2,3 P. Luke.^1,3
¹Department of Surgery, Division of Urology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada; ²Department of Pathology and Laboratory Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada; ³Undergraduate Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
INTRO: The presence of intimal arteritis (v) in renal transplant biopsies (Bx) establishes Grade II-III AVR (Acute Vascular Rejection) according to the Banff Classification. The…