ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2017 American Transplant Congress

    Tacrolimus and Mycophenolate Exposure and Subclinical Tubulo-Interstitial Inflammation in Low Immunological Risk Renal Transplants.

    I. Torres,1 A. Reisaeter,2 F. Moreso,1 A. Asberg,2 M. Perello,1 C. Dörje,2 J. Sellares,1 K. Midtved,2 H. Holdaas,2 D. Seron.1

    1Nephrology, Hospital Universitari Vall d'Hebron, Barcelona, Spain; 2Transplant Medicine, Rikshospitalet Oslo University Hospital, Oslo, Norway

    The aim is to evaluate the relationship between maintenance immunosuppression, subclinical inflammation (i-score plus t-score) and interstitial fibrosis/tubular atrophy (IF/TA) (ci-score plus ct-score) in paired…
  • 2017 American Transplant Congress

    Muscle Mass Is Predictive of Mortality in Obese Renal Transplant Patients.

    J. Souweine,1,3 M. Le Quintrec,1 I. Szwarc,1 V. Pernin,1 G. Mourad,1 J. Cristol,2,3 J. Serre.1

    1Nephrology, University Hospital of Montpellier, Montpellier, France; 2Biochemistry, University Hospital of Montpellier, Montpellier, France; 3PhyMedExp, UMR CNRS 9214, INSERM U1046, University Hospital of Montpellier, Montpellier, France

    Introduction: The impact of obesity (body mass index [BMI] > 30 kg/m[sup2]) on kidney allograft outcomes is controversial. Recent studies found that obesity does not…
  • 2017 American Transplant Congress

    Intraoperative Fluid Management During Pediatric Kidney Transplantation with Less Than 15kg Body Weight Using Transesophageal Echocardiaography as Hemodynamic Parameter.

    Y. Watarai,1 S. Narumi,1 R. Kimura,1 K. Hatazoe,1 M. Okada,1 K. Futamura,1 T. Yamamoto,1 T. Hiramitsu,1 M. Tsujita,1 N. Goto,1 Y. Goto.2

    1Transplant Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Japan; 2Pediatric Nephrology, Nagoya Daini Red Cross Hospital, Nagoya, Japan

    Introduction: To avoid low output syndrome (LOS) and delayed graft function (DGF), precise intraoperative hemodynamic monitoring are mandatory for small pediatric recipients with adults' donor…
  • 2017 American Transplant Congress

    Semi-Automated Pre-Donation Computed Topography (CT) Cortical Renal Volume to Predict Kidney Function in Live Kidney Donors 2 Years Following Donation.

    L.-X. Chen,1 G. Fananapazir,2 R. Benzl,2 M. Corwin,2 S. Stewart,3 C. Troppmann.4

    1Transplant Nephrology, UC Davis Medical Center, Sacramento, CA; 2Radiology, UC Davis Medical Center, Sacramento, CA; 3Biostatistics, UC Davis School of Medicine, Davis, CA; 4Transplant Surgery, UC Davis Medical Center, Sacramento, CA

    Objective: To evaluate whether volume of the remnant kidney based on pre-donation CT and donor age correlates with post-donation 2-year renal function in live kidney…
  • 2017 American Transplant Congress

    Urinary Type III Procollagen (PIIINP) Is Associated with Chronic Allograft Dysfunction and Predicts Graft Survival.

    R. Yilmaz,1 T. Yildirim,1 D. Baydar,2 B. Altun,1 Y. Erdem.1

    1Nephrology Department, Hacettepe University Medical Faculty, Ankara, Turkey; 2Pathology, Hacettepe University Medical Faculty, Ankara, Turkey

    Background: Chronic allograft dysfunction (CAD) is the most important clinical problem in solid organ transplantation. Interstitial fibrosis and tubular atrophy contribute to long term renal…
  • 2017 American Transplant Congress

    Potential Living Kidney Donors (LKD) Concerns About Opting Out and Preferences for an 'Alibi'.

    K. Yu,1 C. Thiessen,1 S. Li,1 D. Dobosz,1 J. Gannon,1 K. Kennedy,2 D. Gray,3 A. Mussell,3 P. Reese,3 S. Kulkarni,1 E. Gordon.2

    1Yale U, New Haven; 2Northwestern U, Chicago; 3U Pennyslvania, Philadelphia

    PurposeTo evaluate potential LKDs comfort discussing opting out with their intended recipient (IR) and preferences for alibisMethodsWe conducted a prospective, longitudinal study of potential LKDs…
  • 2017 American Transplant Congress

    A Novel KPD Mechanism to Increase Transplants When Some Candidates Have Multiple Willing Donors.

    T. Sandholm,1 G. Farina,1 J. Dickerson,2 R. Leishman,3 D. Stewart,3 R. Formica,4 C. Thiessen,4 S. Kulkarni.4

    1Carnegie Mellon U, Pittsburgh; 2U of Maryland, College Park; 3UNOS, Richmond; 4Yale U, New Haven

    Purpose: Current kidney exchanges such as the OPTN Kidney Paired Donation (KPD) program allow candidates to list multiple willing donors, but only one will donate…
  • 2017 American Transplant Congress

    Transplanting Hepatitis C Kidneys into Negative KidnEy Recipients [THINKER] Trial.

    D. Goldberg, E. Blumberg, R. Reddy, S. Nazarian, V. Van Deerlin, J. Trofe-Clarke, M. Levine, D. Sawinski, R. Bloom, P. Abt, P. Reese.

    University of Pennsylvania, Philadelphia

    Background: More than 500 kidneys from HCV+ deceased donors are discarded each year, even though direct acting antiviral therapies have cure rates exceeding 95%. We…
  • 2017 American Transplant Congress

    Blood Transfusion Induced Donor Specific Antibodies Are Associated with Rejection and Graft Failure.

    S. Hassan,1 F. Regan,2,3 C. Brown,4 A. Harmer,3 N. Anderson,3 P. Brookes,5 D. Taube,1 M. Willicombe.1

    1Renal and Transplant Centre, Imperial College Healthcare NHS Trust, London, United Kingdom; 2Haematology, Imperial College Healthcare NHS Trust, London, United Kingdom; 3NHS Blood and Transplant, London, United Kingdom; 4Histocompatibility and Immunogenetics, NHS Blood and Transplant, London, United Kingdom; 5Histocompatibility and Immunogenetics, Imperial College Healthcare NHS Trust, London, United Kingdom

    Introduction: Although it is well known that blood transfusions post-transplant are associated with the development of both HLA and donor specific antibodies [DSAs] and a…
  • 2017 American Transplant Congress

    Impact of Antihypertensive (AHT) Choice and Advagraf® Dose on Immunologic Events in Renal Allografts 24 Months Post-Transplantation (Tx).

    D. Rush,1 S. Cockfield,2 S. Wilson,3 J. Howell,4 FKC-014 Study Group.

    1Health Sciences Centre, Winnipeg, MB, Canada; 2University of Alberta Hospital, Edmonton, AB, Canada; 3Astellas Pharma Global Development, Northbrook, IL; 4Astellas Pharma Global Development, Markham, ON, Canada

    Renal allograft inflammation may be modulated by ACEi- or ARB-type AHTs (renin-angiotensin system (RAS)-targeting drugs that may inhibit calcineurin) or by optimizing tacrolimus (TAC) exposure.…
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