Articles tagged "Kidney transplantation"

2017 American Transplant Congress
Tacrolimus Dose Requirement Based on the CYP3A5 Genotype in Renal Transplant Patients.
L. Qu, Z. Xie, H. Huang, H. Jiang, J. Chen, H. Jiang, H. Jiang, J. Chen, J. Chen, J. Chen.
Kidney Disease Center, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, China
Background The aim of the present study is to determine whether CYP3A5*A and CYP3A5*G genotype is a predictive index of tacrolimus dose requirement, and also…
2017 American Transplant Congress
Association Between Matrix-gla Protein Levels and Aortic Stiffness in Kidney Transplantation.
M. Dinic,¹ N. Maillard,¹ P. Delanaye,² J.-M. Krzesinski,² A.-M. Saint-Remy,² E. Cavalier,³ C. Mariat.¹
¹Nephrology, Dialysis and Renal Transplantation, CHU Nord, Saint Etienne, France; ²Nephrology and Dialysis, University of Liège, CHU Sart Tilman, Liège, Belgium; ³Clinical Chemistry, University of Liège, CHU Sart Tilman, Liège, Belgium
INTRODUCTIONAortic stiffness due to vascular calcifications is commonly observed among kidney transplant recipients and is considered as a predictive factor of poor events such as…
2017 American Transplant Congress
Impact of Six-Month Surveillance Biopsies and Monitoring in Pediatric Renal Transplant Recipients.
J. Lyons,^1,2,3 D. Ranch,^1,2 R. Hall,^1,2,3 P. Maxwell,^1,2,3 K. Hitchman,^1,2 Y. Hirase,³ B. Crowther.^1,2,3
¹University Health System, San Antonio, TX; ²University of Texas Health Science Center San Antonio, San Antonio, TX; ³University of Texas College of Pharmacy, Austin, TX
Purpose: Evaluate the utility of surveillance biopsies and monitoring 6 months post-transplant.Methods: A retrospective single center chart review of pediatric renal transplant recipients from 01/2011–10/2015…
2017 American Transplant Congress
An Argument for Expanding the Simultaneous Liver and Kidney Transplant Criteria: Validity of the New UNOS Allocation Policy.
S. Nagai,¹ M. Safwan,¹ K. Collins,¹ M. Rizzari,¹ D. Moonka,² K. Brown,² A. Patel,³ A. Yoshida,¹ M. Abouljuod.¹
¹Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI; ²Gastroenterology, Henry Ford Hospital, Detroit, MI; ³Nephrology, Henry Ford Hospital, Detroit, MI
Aim: According to the latest simultaneous liver-kidney transplant (SLK) allocation policy by UNOS, allocation of kidney is dependent on duration of low glomerular filtration rate…
2017 American Transplant Congress
Tangible Benefits in Caregiving Burden Among Spouses/Partners of Transplant Patients: Adding “Donor Benefit” to Live Donor Risk Assessment.
S. Rasmussen, L. Duquette, M. Henderson, D. Segev.
JHU, Baltimore
Background The mental and physical health of spouses and co-habiting partners (dyads) are highly correlated. Dialysis entails significant caregiving burden and decreases the quality of…
2017 American Transplant Congress
25-Hydroxyvitamin D [25(OH)D], but Not 1,25-Dihydroxyvitamin D [1,25(OH)₂D], Independently Predicts Kidney Graft Failure: The Wisconsin Allograft Recipient Database (WisARD).
B. Astor,¹ M. Melamed,² D. Mandelbrot,¹ A. Djamali.¹
¹University of Wisconsin School of Medicine and Public Health, Madison, WI; ²Albert Einstein College of Medicine / Montefiore Medical Center, Bronx, NY
Vitamin D deficiency is common in chronic kidney disease and is associated with cardiovascular events and mortality. Kidney transplant recipients are at elevated risk of…
2017 American Transplant Congress
Multi-Stakeholder Perspectives on the Importance of Outcomes for Trials in Kidney Transplantation: An International Best Worse Scaling Survey.
M. Howell,^1,2 N. Evangelidis,^1,2 B. Sautenet,² G. Wong,^1,2,3 J. Craig,^1,2 K. Howard,¹ A. Tong.^1,2
¹School of Public Health, University of Sydney, Sydney, Australia; ²Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, NSW, Australia; ³Centre for Transplant Research, Westmead Hospital, Sydney, NSW, Australia
To optimize the benefits of kidney transplantation, recipients and clinicians should have an agreed, shared management plan. This relies on prioritizing the same outcomes but…
2017 American Transplant Congress
Contribution of New Generation Sequencing to CMV Resistance Analysis in Renal Transplant Recipients (on Behalf of the CMV Resist Group).
C. Danthu,¹ M. Gomes-Mayeras,¹ D. Andouard,² E. Munteanu,¹ R. Moulinas,^1,4 G. Ligat,² S. Hantz,^1,2 J. Rerolle,³ F. Garnier,¹ M. Essig,³ S. Alain.^1,2,4
¹National Reference Center for CMV-Virology, CHU Limoges, Limoges, France; ²UMR Inserm 1092, Université Limoges, Limoges, France; ³Nephrology, CHU Limoges, Limoges, France; ⁴GenoLim/Biscem Genomic Platform, Université Limoges, Limoges, France
Results from the French Cohorts 2006-2010 and OrphaVic (NCTNCT02067169) indicates that fifty percent of graft failures in renal recipients infected by HCMV after treatment with…
2017 American Transplant Congress
More Rapid Decline in Male VS Female Living Kidney Donations (LKD) Varies by Income.
J. Lesage, J. Gill, C. Rose, Y. Joffres, J. Gill.
UBC, Vancouver, Canada
Reasons for the decline in LKD remain uncertain. We hypothesized that there would be a more rapid decline in male vs female LKD and that…
2017 American Transplant Congress
Tacrolimus Intra-Patient Variability Determined from Daily Trough Levels in Adherent Kidney and Liver Transplant Recipients.
A. Leino,¹ T. Kaiser,¹ Y. Zou,² E. King,² A. Vinks,² W. Jiang,⁴ U. Christians,³ E. Woodle,¹ R. Alloway.¹
¹University of Cincinnati, Cincinnati; ²Cincinnati Children's Hospital, Cincinnati; ³University of Colorado, Denver; ⁴Food and Drug Administration, Silver Spring
Drugs are classified as highly variable when intra-patient coefficient of variation (CV%) is > 30%. Tacrolimus (TAC) is characterized as highly variable often without supporting…