Articles tagged "Kidney transplantation"

2017 American Transplant Congress
Correlation of Donor Clinical and Histopathological Characteristics with Graft Function in Kidney Transplant Recipients.
M. Zachariah,¹ C. Yip,¹ M. Zachariah, I. Mallawaarachchi,² A. Dweivedi,² S. Patel,⁴ A. Gundroo,¹ J. Tomaszewski,¹ L. Lin,¹ C. Shirley.¹
¹Medicine, SUNY at Buffalo, Buffalo, NY; ²Biostatistics and Epidemiology, Texas Tech University, El Paso, TX; ³Pathology, SUNY at Buffalo, Buffalo, NY; ⁴Surgery, SUNY at Buffalo, Buffalo, NY
Background: There is lack of consensus in the perceived accuracy of frozen biopsy interpretation. Interobserver variability in assessment of pre-implantation biopsies limits its value to…
2017 American Transplant Congress
Contribution of γδ T-Cell Subsets and IL-17A Release to Ischemia Reperfusion Injury (IRI) and Kidney Allograft Rejection in Mice.
A. Thorenz,¹ S. Rong,¹ N. Völker,¹ R. Chen,¹ J. Bräsen,² H. Haller,¹ C. Klemann,³ F. Gueler.¹
¹Nephrology, Hannover Medical School, Hannover, Germany; ²Pathology, Hannover Medical School, Hannover, Germany; ³Pediatric Surgery, Hannover Medical School, Hannover, Germany
Ischemia reperfusion injury (IRI) contributes to acute allograft injury and to delayed graft function (DGF) which is a trigger for acute rejection after kidney transplantation…
2017 American Transplant Congress
Diagnostic Bronchoscopy in Kidney Transplant Recipients with Acute Respiratory Failure: Risk or Value?
D. Khadzhynov, J. Deissler, F. Halleck, L. Lehner, K. Budde, O. Staeck.
Nephrology, Charité Universitaetsmedizin, Berlin, Germany
Introduction:Few data evaluates the differential diagnostic value of bronchoalveolar lavages (FO-BAL) in kidney transplant recipients (KTR) with acute respiratory failure (ARF). We describe the results…
2017 American Transplant Congress
Alemtuzumab Induction Is Associated with a Lower Incidence of BK Virus Nephropathy Compared with IL2RA Induction.
A. Gueret-Wardle, S. Hassan, G. Lucisano, C. Roufosse, M. Willicombe, D. Taube.
Renal Medicine, West London Renal and Transplant Centre, London, United Kingdom
Introduction:BK polyoma virus associated nephropathy [BKVAN] is a major cause of allograft dysfunction and graft loss occurring in up to 10% of kidney allograft recipients…
2017 American Transplant Congress
Donor and Recipient Outcomes with Trans-Umbilical Laparoendoscopic Single-Site Donor Nephrectomy.
H. El Hennawy, A. Fahmy.
Surgery Department, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia
Introduction: Laparoendoscopic single-site donor nephrectomy (LESS-DN) emerged as an advancement to standard laparoscopic surgery with its advantage of using a single small incision concealed in…
2017 American Transplant Congress
The Evolution of Hepatitis B Surface Antibody (Anti-HBs) Titer of the Kidney Transplant Recipients: A 5-Year Experience Guideline for the Optimal Maintaining Immunization.
W. Chancharoenthana, A. Leelahavanichkul, S. Wattanatorn, Y. Avihingsanon, K. Praditpornsilpa, N. Townamchai.
Division of Nephrology, Department of Medicine, Chulalongkorn University, Bangkok, Thailand
Background: Immunization against hepatitis B virus (HBV) in kidney transplantation (KT) recipients is recommended as KDIGO guideline. Although hepatitis B surface antibody (anti-HBs) titer of…
2017 American Transplant Congress
SIRPα⁺ DCs and the Time-Dependent CD4⁺CD8⁺ Double Positive T Cell Infiltration in Accepted Renal Allografts.
T. Ashry,^1,2 C. Yang,² B. Jiang,² D. Ndishabandi,² P. Russel,^1,2 R. Colvin,^1,2 J. Madsen,^1,2 A. Alessandrini.^1,2
¹HMS, Boston; ²MGH, Boston
IntroductionIn 2015 Overgaard and colleagues proposed that double positive T (DPT) cells, usually unique to the thymus, represent more than a developmental phase as extrathymic…
2017 American Transplant Congress
Biopsies (Bx) of Renal Allografts with Antibody- + Cell-Mediated Rejection (ABMR/CMR) Exhibit Gene Expression Signatures from Both Types of Rejection.
H. Zhang,¹ C. Nast,² J. Doldron,² M. Cheung,² J. Mirocha,³ J. Kahwaji,¹ A. Vo,¹ S. Jordan,¹ M. Toyoda.¹
¹Transplant Immunology Laboratory, Cedars-Sinai Medical Center, Los Angeles; ²Pathology, Cedars-Sinai Medical Center, Los Angeles; ³Biostatistics Center, Cedars-Sinai Medical Center, Los Angeles
Background: In HLA-sensitized kidney transplant patients (Pts) the concomitant presence of ABMR/CMR on Bx is associated with a more severe and (&) usually irreversible injury…
2017 American Transplant Congress
Outcome and Risk Factors of Recurrent Focal Segmental Glomerulosclerosis After Kidney Transplantation.
G. Chen, C. Wang, Z. Wu, J. Zhang, S. Yu, C. Wang, J. Qiu, L. Chen.
Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
Background Recurrent focal segmental glomerulosclerosis(FSGS) is common after kidney transplantation . We conducted a retrospective cohort study with the aim to investigating the long-term outcome…
2017 American Transplant Congress
A Phase Ib, Open Label, Single Arm Study to Assess the Safety, Pharmacokinetics, and Impact on Humoral Sensitization of SANGUINATE Infusion in Patients with End-Stage Renal Disease.
B. Abu Jawdeh,¹ E. Woodle,¹ A. Leino,¹ T. Dorst,¹ M. Abdallah,¹ A. Govil,¹ D. Byczkowski,² H. Misra,² A. Abuchowski,² R. Alloway.¹
¹U.Cincinnati, OH; ²Prolong Pharmaceuticals, NJ
Purpose:The endeavor and resources spent to study desensitization haven't been matched by an effort to investigate strategies to prevent sensitization.The purpose of this study was…