ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2017 American Transplant Congress

    Propensity-Matched Comparison of Diabetic Patients and Non-Diabetic Patients in Living Donor Kidney Transplantation.

    C. Baek,1 H. Kim,1 W. Yang,1 D. Han,2 S.-K. Park.1

    1Division of Nephrology, Department of Internal Medicine, Asan Medical Center, Seoul, Republic of Korea; 2Department of Surgery, Asan Medical Center, Seoul, Republic of Korea

    Background: Kidney transplantation (KT) reportedly provides a significant survival advantage over dialysis in diabetic patients. However, KT outcome in diabetic patients compared with that in…
  • 2017 American Transplant Congress

    Impairment of Glucose Tolerance After Pediatric Kidney Transplant Is Associated with Worse Systemic Insulin Sensitivity Rather Than Fall in Insulin Secretion.

    D. Iwami, K. Hotta, H. Sasaki, T. Hirose, H. Higuchi, Y. Takada, N. Shinohara.

    Renal and Genitourinary Surgery, Hokkaido University, Sapporo, Hokkaido, Japan

    Introduction and Objective: Tacrolimus and steroid are considered to affect insulin secretion and insulin sensitivity, respectively, resulting in worse glucose tolerance after pediatric kidney transplant…
  • 2017 American Transplant Congress

    The Impact of Tacrolimus and MPA Derivative Immunosuppression on Acheived GFR in Recipients without Rejection: A Comparison of GFR of Living Donor Recipient Pairs at Six Months Post-Transplant.

    D. Keith.

    Medicine, Division of Nephrology, Sacred Heart Hospital, Pensacola, FL

    Analysis of the difference in estimated GFR (eGFR) of living donor recipient pairs at six months post-transplant showed that increased use of tacrolimus and MPA…
  • 2017 American Transplant Congress

    Adjunctive Thymoglobulin with Proteasome Inhibitor Based Treatment of Late Mixed Acute Rejection.

    A. Lichvar,1 A. Leino,1 S. Tremblay,1 A. Shields,2 F. Paterno,1 A. Govil,1 M. Anand,1 T. Diwan,1 J. Kremer,2 R. Alloway,1 E. Woodle.1

    1University of Cincinnati, Cincinnati; 2The Christ Hospital, Cincinnati

    Proteasome inhibitor (PI) containing regimens treat mixed acute rejection (MAR) at least in part due to elimination of donor specific antibody (DSA) and via effects…
  • 2017 American Transplant Congress

    Race, Admissions, and Renal Transplant Waitlisting.

    R. Lynch, R. Zhang, R. Patzer, C. Larsen, A. Adams.

    Surgery, Emory University, Atlanta, GA

    Background: We have previously shown that increased hospitalization while listed for renal transplantation is associated with excess waitlist mortality, reduced odds of transplantation, and inferior…
  • 2017 American Transplant Congress

    Kidney Transplant Rejection Associated with DQ Eplet Mismatches.

    S. Chakola,1 P. Warner,2 N. Andeen,3 B. Najafian,3 N. Leca,1 C. Blosser.1

    1Medicine, University of Washington, Seattle, WA; 2Bloodworks Northwest, Seattle, WA; 3Pathology, University of Washington, Seattle, WA

    The presence of anti-HLA antibodies is associated with acute rejection, allograft dysfunction and earlier graft loss. HLA antibodies are recognized as being specific to these…
  • 2017 American Transplant Congress

    Graft Survival in De Novo Donor-Specific Antibodies and Positive Flow Crossmatch Kidney Transplants Is influenced by Class I and Class II.

    S. Montag,1,2 B. Ho,1 H. Bhagat,3 E. Lee,3,4 K. Atiemo,1 A. Daud,1 R. Kang,1 L. Zhao,1,2 J. Schwartz,3 D. Ladner.1

    1Northwestern University Transplant and Outcomes Research Collaborative (NUTORC), Chicago; 2Dept of Preventive Medicine, Northwestern University, Chicago; 3Astellas Pharma Global Development, Northbrook; 4Now with UCB, Atlanta

    Patients with de novo donor-specific antibodies (dnDSA) show inferior graft survival in numerous small studies. We assessed the effect of dnDSA on graft and patient…
  • 2017 American Transplant Congress

    Compartmental Infiltration of Kidney Allograft with Monocyte-Macrophage Subtypes Defines the Type of Rejection.

    T. van den Bosch,1 M. Clahsen-van Groningen,2 F. Rezaee,3 D. Hesselink,1 D. Nieboer,4 E. Steyerberg,4 C. Baan,1 A. Rowshani.1

    1Internal Medicine, Erasmus University Medical Center, Rotterdam, Netherlands; 2Pathology, Erasmus University Medical Center, Rotterdam, Netherlands; 3Gastroenterology, Erasmus University Medical Center, Rotterdam, Netherlands; 4Public Health, Erasmus University Medical Center, Rotterdam, Netherlands

    Purpose: Rejection significantly worsens the graft function and survival. We studied monocyte-macrophage compartmental infiltration of 62 kidney transplant biopsies with diagnosis of: acute antibody mediated…
  • 2017 American Transplant Congress

    Venous Thromboembolism and the Risk of Death and Graft Loss in Kidney Transplant Recipients.

    N. Lam,1 A. Garg,2 G. Knoll,3 J. Kim,4 K. Lentine,5 E. McArthur,6 K. Naylor,6 S. Bota,6 M. Sood.3

    1University of Alberta, Edmonton, Canada; 2Western University, London, Canada; 3University of Ottawa, Ottawa, Canada; 4University of Toronto, Toronto, Canada; 5Saint Louis University School of Medicine, St. Louis; 6Institute for Clinical Evaluative Sciences, London, Canada

    Background: The incidence of venous thromboembolism (VTE) in kidney transplant recipients varies widely in the literature. The implications of VTE for morbidity and mortality in…
  • 2017 American Transplant Congress

    Induction of Delayed Renal Allograft Tolerance Using Only Clinically Available Reagents in Non-Human Primates.

    K. Hotta, T. Oura, A. Dehnadi, S. Boskovic, M. Matsunami, I. Rosales, N. Smith, R. Colvin, A. Cosimi, T. Kawai.

    Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA

    Background: We have previously reported successful induction of renal allograft tolerance following a period of conventional immunosuppression (Delayed tolerance) using nonmyeloablative conditioning that included anti-CD154…
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