ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2017 American Transplant Congress

    Efficacy and Safety of Everolimus with Reduced-Exposure Tacrolimus and Corticosteroid Withdrawal in De Novo Pediatric Renal Transplant Recipients: 12-Month Results from the CRADLE Study.

    R. Ettenger,1 B. Tönshoff,1 H. Tedesco,1 L. Dello Strologo,1 S. Marks,1 L. Pape,1 E. Martzloff,2 B. Rauer,2 J. Ng,3 P. Lopez.2

    1A2314 Study Group, Los Angeles; 2Novartis Pharma AG, Basel, Switzerland; 3Novartis Pharmaceutical Corporation, East Hanover

    PURPOSE: We present 12-month (M) results from the CRADLE study (NCT01544491) that assessed efficacy and safety of everolimus (EVR) with reduced-exposure tacrolimus (rTAC) and early…
  • 2017 American Transplant Congress

    Gene Expression Signature of Subclinical Allograft Kidney ABMR Compared to Clinical ABMR.

    O. Aubert,1 C. Lefaucheur,1 S. Higgins,1 L. Hidalgo,2 J. Duong Van Huyen,1 D. Viglietti,1 X. Jouven,1 D. Glotz,1 C. Legendre,1 P. Halloran,2 A. Loupy.1

    1Paris Translational Research Center for Organ Transplantation, Paris, France; 2ATAGC, Edmonton, France

    BackgroundAntibody-mediated rejection (ABMR) is characterized by a heterogeneous presentation. It occurs in clinically stable patients (sABMR) or in patients with allograft dysfunction (ABMR), but only…
  • 2017 American Transplant Congress

    Complement Markers in Immunoadsorption Combined with Membrane Filtration.

    P. Malvezzi,1 F. Defendi,2 F. Eskandary,3 T. Jouve,1 L. Rostaing,1 C. Dumestre-Perard,2 G. Böhmig.3

    1Clinique de Néphrologie, CHUGA, Grenoble, France; 2Laboratoire d'Immunologie, CHUGA, Grenoble, France; 3Department of Medicine III, Medical University, Vienna, Austria

    Introduction: In HLA incompatible transplantation pretransplant desensitization is mandatory in order to eliminate the donor-specific alloantibody that might fix complement (C). In a randomized crossover…
  • 2017 American Transplant Congress

    The Use of Kidneys from Deceased Donors Over 80 Years in Kidney Transplantation.

    M. Pérez-Sáez,1 E. Arcos,2 J. Comas,2 J. Pascual.1

    1Nephrology, Hospital del Mar, Barcelona, Spain; 2Organització Catalana de Trasplantaments, Barcelona, Spain

    Patient survival is longer after kidney transplantation (KT) compared with remaining in the waiting list on dialysis. We have questioned if this is true also…
  • 2017 American Transplant Congress

    The Role of Urinary Chemokines in Distinguishing Causes of Renal Allograft Dysfunction.

    S. Chong,1 R. Fernando,2 M. Harber,1 C. Magee.1

    1UCL Centre for Nephrology, Royal Free Hospital, London, United Kingdom; 2Anthony Nolan Laboratories, Royal Free Hospital, London, United Kingdom

    The aetiology of renal transplant dysfunction is varied, and diagnosis often relies upon transplant biopsy, an invasive procedure that carries significant risk. Availability of a…
  • 2017 American Transplant Congress

    Bacteremia in Kidney Transplant Recipients: Incidence, Risk Factors, and Outcomes.

    S. Brar, Y. Wang, A. Cannitelli, Y. Li, O. Famure, S. Husain, J. Kim.

    Multi-Organ Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada

    Background: Bloodstream infections or bacteremia is a serious complication after kidney transplantation. The incidence, risk factors, and outcomes of bacteremia among kidney transplant recipients have…
  • 2017 American Transplant Congress

    Incidence and Risk Factors for Cervical Dysplasia Associated to Human Papillomavirus Infection in Women with Kidney Transplant.

    I. Parra-Avila, J. Alberu, L. Marino-Vazquez, L. Morales-Buenrostro, R. Rosado-Canto.

    Department of Nephrology and Transplant, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico

    Introduction: Women with kidney transplant (KT) have an increased risk for Human Papillomavirus (HPV) infection, which is related to cervical cancer, reaching an incidence of…
  • 2017 American Transplant Congress

    Reasons for Ineligibility for Kidney Donation by Race: Gap for Blacks Represented by Modifiable Factors, However Are Big Hurdles to Overcome.

    D. Simpson,1 M. Levine,1 S. Amaral.2

    1Hospital of the University of Pennsylvania, Philadelphia, PA; 2Children's Hospital of Philadelphia, Philadelphia, PA

    Background: It is well-recognized that blacks are much less likely to receive living donor kidney transplants. Improved characterization of the reasons for differences in living…
  • 2017 American Transplant Congress

    The Impact of Hepatitis C Treatment on GFR and Immunosuppression in Renal Transplant Recipients.

    J. Husson, R. Adekunle, B. Ravichandran, P. Mathur, S. Jonchhe, K. Stafford.

    University of Maryland Medical Center, Baltimore, MD

    Background: Renal transplant recipients (RTRs) with HCV are at an increased risk of graft rejection, making treatment of HCV in this population of the utmost…
  • 2017 American Transplant Congress

    Mechanisms of Fibrosis in the Allograft Kidney: RNA-seq Based Analysis Using Formalin Fixed Biopsies.

    G. Zeng,2 L. Pan,1 Z. Lyu,1 Y. Huang,2 P. Randhawa.2

    1Department of Nephrology, Guangxi Medical University, Nanning, Guangxi, China; 2Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA

    Development of allograft fibrosis determines long term graft survival but our understanding of this important complication is incomplete. To gain further insight into this problem…
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