Articles tagged "Kidney transplantation"

2017 American Transplant Congress
Benefits of Induction in Recipients of Acute Renal Failure Donor Kidneys.
M. Barrett, A. Smith, K. Woodside, R. Sung.
University of Michigan, Ann Arbor
Kidneys from donors with acute renal failure (ARF) are often discarded due to concerns for DGF and graft failure. Induction immunosuppression can be used to…
2017 American Transplant Congress
When Does the Learning Curve End? A High-Volume Single Center Experience with Laparoscopic Donor Nephrectomy Over 16 Years.
S. Yamanaga,^1,2,3 A. Posselt,¹ C. Freise,¹ C. Niemann,¹ A. Rosario,¹ D. Fernandez,¹ T. Kobayashi,³ A. Ahearn,⁴ M. Tavakol,¹ S.-M. Kang.¹
¹Division of Transplant Surgery, Department of Surgery, University of California San Francisco, San Francisco, CA; ²Department of General Surgery, Japanese Red Cross Kumamoto Hospital, Kumamoto, Japan; ³Department of Renal Transplant Surgery, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan; ⁴Department of Transplant Surgery, UMass Memorial Medical Center, Worcester, MA
Purpose: No studies for any type of surgery have examined learning curves beyond a decade or 100 cases because surgeon turnover and lack of complete…
2017 American Transplant Congress
Immune Sensitization During Pregnancy Reduces Long-Term Benefit for Kidney Recipients of Offspring Living Donors.
J. Cohen,¹ L. Owei,² D. Sawinski,¹ P. Porrett.²
¹Medicine, University of Pennyslvania, Philadelphia, PA; ²Surgery, University of Pennsylvania, Philadelphia, PA
Background Offspring-to-mother kidney transplantations are associated with excellent short-term outcomes given the accuracy of histocompatibility testing and potency of immunosuppression. However, immunologic memory responses in…
2017 American Transplant Congress
Risk Factors and Consequences of De Novo Anti-HLA Donor Specific Antibodies in Kidney Transplant Recipients: The Force Awakens.
B. Javaid, S. Rosen-Bronson, D. Li, M. Awwad, A. Gilbert, S. Ghasemian, J. Verbesey, P. Abrams, M. Grafals, J. Fenton, C. Cannon, J. Rapisura, J. Moore, M. Cooper.
Kidney and Pancreas Transplant Program, MedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital, Georgetown University School of Medicine, Washington, DC
Background: Presence of anti-HLA donor specific antibodies (DSAs) has been associated with inferior kidney transplant outcomes. Identification of risk factors for de novo DSAs could…
2017 American Transplant Congress
C3d-Binding Anti-DQ DSA Is Associated with a High Risk for Late ABMR and Graft Failure in Stable Kidney Transplant Recipients.
D. Lee,¹ B. Kim,² J. Kim,³ I. Kim,⁴ M. Chun.⁵
¹Medicine, Maryknoll Medical Center, Busan, Republic of Korea; ²Laboratyory Medicine, Maryknoll Medical Center, Busan, Republic of Korea; ³Surgery, Maryknoll Medical Center, Busan, Republic of Korea; ⁴Urology, Maryknoll Medical Center, Busan, Republic of Korea; ⁵Pathology, Maryknoll Medical Center, Busan, Republic of Korea
Introduction:Donor specific anti-HLA antibodies (DSA) are a major cause of antibody-mediated rejection (ABMR) and poor graft outcome in kidney transplant recipients (KTR). Critical issue is…
2017 American Transplant Congress
The American Transplant Congress Effect on Kidney Discard Rates in the United States.
D. Abdelwahab,¹ G. Wei,² I. Hall.²
¹Mayo Clinic, Scottsdale, AZ; ²University of Utah, Salt Lake City, UT
Background: Deceased-donor kidneys with high kidney donor risk index (KDRI) are often discarded despite evidence that certain candidates would have better survival accepting these kidneys…
2017 American Transplant Congress
Intended and Unexpected Impact of the New Kidney Allocation System on a Large Volume Transplant Program.
A. de Mattos, M. Alnimri, L.-X. Chen, J. Sageshima, C. Santhanakrishnan, R. Perez.
University of California Davis, Sacramento, CA
On December 4, 2014 the new Kidney Allocation System (KAS) went into effect in the United States. The intentions of KAS were to increase the…
2017 American Transplant Congress
Clinically Relevant Immunosuppression Promotes MCMV Reactivation and Dissemination Following Transplantation of Latently Infected Kidneys.
Z. Zhang,¹ S. Yan,¹ L. Zhao,¹ S. Kurian,² M. Hummel,¹ D. Salomon,² M. Abecassis.¹
¹Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago; ²Dept. of Molecular & Experimental Medicine, The Scripps Research Institute, La Jolla
Reactivation of latent Cytomegalovirus (CMV) is an important problem facing clinical transplantation. We have previously described a model for murine CMV (MCMV) reactivation following kidney…
2017 American Transplant Congress
Donor Derived and BK Virus Positive Urologic Cancers After Renal Transplantation.
V. Hellström,¹ G. Tufveson,¹ A. Wallgren,² A. Loskog,² E. Larsson,² T. Töttermann,² M. Bengtsson,² A. Laurell,² C. Lundberg,¹ B. Holmström,¹ G. Enblad,² T. Lorant.¹
¹Department of Surgical Sciences, Uppsala University, Uppsala, Sweden; ²Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden
Background. Donor-derived tumours in organ recipients develop from donor tissue with no known pre-existing malignancy in the donor. In addition, polyoma BK virus (BKV) might…
2017 American Transplant Congress
Neutropenia in Kidney and Liver Transplant Recipients: Risk Factors and Consequences.
T. Mavrakanas,¹ M. Fournier,² S. Clairou,² J. Amiel,² D. Vinh,³ C. Coursol,² D. Thirion,² M. Cantarovich.⁴
¹Medicine, Division of Nephrology, McGill University Health Center, Montreal, QC, Canada; ²Pharmacy, McGill University Health Center, Montreal, QC, Canada; ³Medicine, Division of Infectious Diseases, McGill University Health Center, Montreal, QC, Canada; ⁴Medicine, Division of Nephrology, Multi-Organ Transplant Program, McGill University Health Center, Montreal, QC, Canada
Aim: This study aimed to: 1) Define the risk factors associated with neutropenia within the first year post kidney or liver transplantation; 2) Describe the…