2017 American Transplant Congress
Kidney Waitlist Management: The Readiness Model of Predicting Transplants Under the Kidney Allocation System.
Transplant Center, Massachusetts General Hospital, Boston, MA
Based on the Organ Procurement and Transplantation Network data, between 2001 and 2016 the national kidney wait-list has grown from 51,271 to 100,791 (97%). At…2017 American Transplant Congress
EXPANDER-1: Exploring Renal Transplants Using Hepatitis-C Infected Donors for HCV-Negative Recipients.
Kidneys from hepatitis C-infected (HCV+) donors are underutilized in an era of severe organ shortage. In an effort to expand the donor pool, we evaluated…2017 American Transplant Congress
Outcomes of Protocol Allograft Kidney Biopsy in DeNovo Donor Specific Antibodies.
University of Wisconsin, Madison, WI
There is limited information about the role of protocol kidney biopsies for de-novo donor specific antibodies (dnDSA) in kidney transplant recipients (KTR). We initiated monitoring…2017 American Transplant Congress
De Novo Low-Dose Sirolimus versus Mycophenolate Mofetil in Combination with Extended-Release Tacrolimus in Kidney Transplant Recipients.
Previous studies reported that tacrolimus (TAC) with high-dose sirolimus (SRL) was associated with worse outcomes in kidney transplantation, compared to TAC with mycophenolate mofetil (MMF.).…2017 American Transplant Congress
Waitlist Desensitization and the Rate of Deceased Donor Kidney Transplantation After Implementation of the Kidney Allocation System.
Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, CA
Background:At Cedars Sinai Medical Center (CSMC), candidates with calculated panel reactive antibodies (cPRA) ≥30% (based on unacceptable antigens with MFI≥15,000) are desensitized while awaiting transplant.…2017 American Transplant Congress
Eight Year Follow-Up of a Phase 2 Clinical Trial to Induce Tolerance in Living Donor Renal Transplant Recipients.
1Northwestern University, Chicago; 2U of Louisville, Louisville
36 subjects have been transplanted in a phase 2 protocol (IDE 13947) to induce tolerance in recipients of living donor renal allografts (KTx). The protocol…2017 American Transplant Congress
Impact of Cold Ischemia Time on Outcomes in Kidney Paired Donation (KPD).
1UWHealth, Madison; 2UMN, Minneapolis
Cold ischemic time (CIT) is an established risk factor for delayed graft function (DGF) in DD kidney tx. Impact of prolonged CIT, in the context…2017 American Transplant Congress
Composite Prognostic Score Improves Clinical Benefit in Kidney Recipients Receiving Standard of Care Therapy for Antibody-Mediated Rejection.
Paris Translational Research Center for Organ Transplantation, Paris, France
There is a marked heterogeneity in AMR patients' prognosis after SOC treatment including plasma exchange (PE) and intravenous immunoglobulins (IVIG). We investigated whether the use…2017 American Transplant Congress
A Humanized Anti-CD47 Monoclonal Antibody Therapy Alleviates Ischemia-Reperfusion Injury of Porcine Renal Allografts Donated After Cardiac Death.
PURPOSE: This study investigated whether the blockade of the CD47 signaling pathway, which is involved in vascular endothelial nitric oxide regulation, reduces ischemia-reperfusion injury (IRI)…2017 American Transplant Congress
Neutropenia in Kidney Transplantation: A Hidden Threat to Graft Survival.
Medstar Georgetown Transplant Institute, Washington, DC
IntroductionNeutropenia is a common complication after kidney transplantation resulting in a reduction of immunosuppression and the use of granulocyte colony-stimulating factors (G-CSF) which can increase…
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