ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2017 American Transplant Congress

    HLA Eplet Mismatches Predict DSA Formation, Graft Survival, and Re-Transplantation Rate in Pediatric Renal Transplantation.

    M. Sypek,1,2 S. Hiho,3 L. Cantwell,3 P. Hughes,2 A. Le Page,4 J. Kausman.1

    1Royal Children's Hospital, Melbourne, Australia; 2Royal Melbourne Hospital, Melbourne, Australia; 3Victorian Transplant and Immunogenetics Service, Melbourne, Australia; 4Monash Children's Hospital, Melbourne, Australia

    The potential benefits of HLA epitope based matching are greatest for pediatric recipients, however, there is little published data on the association of epitope mismatches…
  • 2017 American Transplant Congress

    A Prospective Iterative Trial of Carfizomib-Based Desensitization Trial: Initial Comparative Observations.

    S. Tremblay,1 A. Shields,1,2 R. Alloway,1 P. Brailey,1 A. Leino,1 A. Lichvar,1 B. Abu Jawdeh,1 J. Driscoll,1 A. Girnita,1 E. Woodle.1

    1U of Cincinnati, Cincinnati; 2Christ Hospital, Cincinnati

    Carfilzomib (CFZ) is a 2nd generation proteasome inhibitor different form bortezomib in that it irreversibly disables 20s and 26s proteasomes.Results from the first 2 phases…
  • 2017 American Transplant Congress

    Post-Transplant Reduction in Pre-Existing Donor-Specific Antibody Levels After Belatacept- vs Cyclosporine-Based Immunosuppression.

    R. Bray,1 H. Gebel,1 R. Townsend,2 M. Polinsky,2 L. Yang,2 U. Meier-Kriesche,2 C. Larsen.1

    1Emory University, Atlanta, GA; 2Bristol-Myers Squibb, Lawrenceville, NJ

    Purpose: We explored the effect of belatacept (bela)- and cyclosporine (CsA)-based immunosuppression (IS) on pre-existing donor-specific antibody (DSA) levels by mean fluorescence intensity (MFI) in…
  • 2017 American Transplant Congress

    Dementia and Alzheimer's Disease Among Older Kidney Transplant Recipients.

    M. McAdams DeMarco, S. Bae, N. Chu, A. Gross, C. Brown IV, E. Oh, P. Rosenberg, K. Neufeld, R. Varadhan, M. Albert, J. Walston, D. Segev.

    Johns Hopkins, Baltimore, MD

    Background: Kidney transplantation (KT) is a growing treatment option for older ESRD patients. Older recipients may develop post-KT dementia and Alzheimer's disease (AD) associated with…
  • 2017 American Transplant Congress

    The Impact of the New Kidney Allocation System on Length of Dialysis Prior to Transplantation.

    T. Melanson,1 M. Basu,1 L. Plantinga,1 S. Pastan,1 S. Mohan,2 R. Patzer.1

    1Emory University, Atlanta; 2Columbia University, New York

    Introduction: The Kidney Allocation System (KAS) changed the starting point for calculating waiting time for patients on the kidney transplant (KTx) waitlist from the time…
  • 2017 American Transplant Congress

    Gene Expression During Development of Chronic Antibody-Mediated Rejection in Renal Allografts from Non-Human Primates: Validation of Markers Used in Humans and Sequential Changes in Protocol Biopsies.

    B. Adam,1 R. Smith,2 M. Matsunami,2 I. Rosales,2 B. Afzali,1 T. Oura,2 A. Cosimi,2 T. Kawai,2 R. Colvin,2 M. Mengel.1

    1University of Alberta, Edmonton, Canada; 2Harvard Medical School and Massachusetts General Hospital, Boston

    Background: RNA transcript measurement is a promising adjunct for the diagnosis and classification of antibody-mediated rejection (ABMR), however most technologies require specially processed biopsy samples.…
  • 2017 American Transplant Congress

    Gut Microbiota-Urinary Tract Infection Axis in Kidney Transplant Recipients.

    J. Lee,1 M. Mcgruder,1 L. Zhang,1 D. Dadhania,1 M. Thangamani,1 L. Ling,2 Y. Taur,2 E. Pamer,2 M. Suthanthiran.1

    1Medicine, Weill Cornell, New York, NY; 2Medicine, Memorial Sloan Kettering Cancer Center, New York, NY

    Introduction. The gut microbiota has recently been identified as a risk factor for development of infectious complications like bacteremia; herein, we evaluated the relationship between…
  • 2017 American Transplant Congress

    Stable Deceased Donor Transplantation Rates Among Pediatric Candidates Post-KAS Implementation.

    B. Shelton,1 C. Ray,1 D. Sawinski,2 R. Reed,1 P. MacLennan,1 J. Locke.1

    1University of Alabama at Birmingham, Birmingham; 2University of Pennsylvania, Philadelphia

    Background: The Kidney Allocation System (KAS) was implemented in December 2014 and increased access to deceased donor kidney transplant (DDKT) for highly sensitized candidates. Concerns…
  • 2017 American Transplant Congress

    Temporal Trends and Variation in BMI Thresholds for Living Donation Across the US.

    A. Naik,1 D. Cibrik,1 A. Sakhuja,2 K. Lentine.3

    1U Michigan, Ann Arbor; 2Mayo Clinic, Rochester; 3St. Louis U, St Louis

    The acceptable BMI threshold for living kidney donation is controversial. We examined the variability in center acceptance of living donors with high Body Mass Index…
  • 2017 American Transplant Congress

    Robotic Kidney Transplantation: Bakirkoy Experience.

    S. Sahin,1 V. Tugcu,1 A. Yavuzsan,1 F. Akbay,2 S. Apaydin.2

    1Urology, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey; 2Nephrology, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey

    INTRODUCTION AND OBJECTIVES: As minimal invasive treatments develop, most urologists have preferred minimally invasive methods in recent years. There is a great shift through laparoscopic…
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