ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Advanced Search

Long-Term Outcomes in HIV(+) Kidney Re-Tranpslant (ReTx) Recipients vs. Primary Transplant (PrimTx) Recipients.

G. Malat, S. Guy, K. Ranganna, D. Reich, G. Xiao, S. Talluri, M. Harhay, L. Levin Mizrahi, C. Culkin.

Drexel University College of Medicine, Philadelphia

Meeting: 2017 American Transplant Congress

Abstract number: D120

Keywords: HIV virus, Kidney transplantation, Outcome, Retransplantation

Session Information

Date: Tuesday, May 2, 2017

Session Name: Poster Session D: Kidney: Acute Cellular Rejection

Session Time: 6:00pm-7:00pm

 Presentation Time: 6:00pm-7:00pm

Location: Hall D1

Related Abstracts
  • Kidney Re-Transplantation (reTx) in Patients with Post-Transplant Lymphoproliferative Disorder (PTLD)
  • Similar Outcomes Can Be Expected Among HIV (+) Kidney Transplant Recipients (HIV+ Tx) Vs. HIV (-) Kidney Transplant Recipients (HIV- Tx) Receiving Similar Immunosuppression Protocols

Hahnemann University Hospital has performed 113 kidney transplants, including 7 ReTx. Herein we describe characteristics and allograft outcomes of HIV(+) kidney transplant recipients based on ReTx status.

Methods: We compared recipient, donor, allograft characteristics between ReTx(n=7) and PrimTx(n=106) HIV(+) kidney recipients at a single center. Immunosuppression consisted of antibody induction (basiliximab (n=112), antithymocyte globulin (n=1,ReTx), and concomitant IVIG (n=19, 2 ReTx/17 CRD)), calcineurin-inhibitor, antiproliferatives, and prednisone. Rejections and allograft outcomes were analyzed between the two cohorts.

Results: Patient characteristics were similar, except more female ReTx (Table 1).Rejection rates were increased in the ReTx cohort (figure 1), which likely impacted survival. Kaplan-Meier curve for allograft survival is shown in figure 2.

Conclusion: Both PrimTx and ReTx HIV(+) kidney recipients are at high risk for rejection and allograft failure. Future studies may focus on the ideal immunosuppression required to improve outcomes for HIV(+) ReTx recipients.

ReTx(n=7) PrimTx(n=106) p-value
Recipient Age (years) 47±7 48±0 0.81
Male 57% 88% 0.03
African American 100% 80% 0.72
Protease Inhibitor based ART 71% 51% 0.29
HCV(+) 71% 38% 0.08
Pre-transplant PRA 30±43% 3±10% 0.44
Deceased Donor 100% 89% 0.40
Donation after Cardiac Death 14% 10% 0.75
KDRI 1.412±0.69 1.318±0.48 0.83
HLA mismatch 4.1±1.1 4.2±1.6 0.57
Delayed Graft Function 57% 57% 0.98

CITATION INFORMATION: Malat G, Guy S, Ranganna K, Reich D, Xiao G, Talluri S, Harhay M, Levin Mizrahi L, Culkin C. Long-Term Outcomes in HIV(+) Kidney Re-Tranpslant (ReTx) Recipients vs. Primary Transplant (PrimTx) Recipients. Am J Transplant. 2017;17 (suppl 3).

  • Tweet
  • Email
  • Print

To cite this abstract in AMA style:

Malat G, Guy S, Ranganna K, Reich D, Xiao G, Talluri S, Harhay M, Mizrahi LLevin, Culkin C. Long-Term Outcomes in HIV(+) Kidney Re-Tranpslant (ReTx) Recipients vs. Primary Transplant (PrimTx) Recipients. [abstract]. Am J Transplant. 2017; 17 (suppl 3). https://atcmeetingabstracts.com/abstract/long-term-outcomes-in-hiv-kidney-re-tranpslant-retx-recipients-vs-primary-transplant-primtx-recipients/. Accessed April 23, 2021.

« Back to 2017 American Transplant Congress

Most Viewed Abstracts

  • This Week
  • This Month
  • All Time
  • Subtherapeutic Low Tacrolimus Trough Levels (≤3.5 Ng /ml) Are A Risk Factor For Acute Rejection And Creatinine Doubling.
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Deceased Non-A2 Donor ABO-Incompatible Liver Transplantation – Promising Results with Anti-A/B Antibody Reduction Both Pre- and Post-Transplant.
  • Penis Transplantation: First U.S. Experience.
  • Subtherapeutic Low Tacrolimus Trough Levels (≤3.5 Ng /ml) Are A Risk Factor For Acute Rejection And Creatinine Doubling.
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Penis Transplantation: First U.S. Experience.
  • Live Related Kidney Transplant Experience in Abuja, Nigeria – First Eight Cases Ever.
  • Penis Transplantation: First U.S. Experience.
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Evidence of a Clinically Significant Drug-Drug Interaction between Cannabidiol and Tacrolimus: A Case Report
  • Kidney Dialysis after Heart Transplantation: The Short and Long Term Outcomes

Visit Our Partner Sites

American Transplant Congress (ATC)

Visit the official site for the American Transplant Congress »

American Journal of Transplantation

The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

American Society of Transplantation (AST)

An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

American Society of Transplant Surgeons (ASTS)

The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

Copyright © 2013-2021 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

Privacy Policy | Terms of Use

loading Cancel
Post was not sent - check your email addresses!
Email check failed, please try again
Sorry, your blog cannot share posts by email.
This site uses cookies: Find out more.