Articles tagged "Kidney transplantation"

2022 American Transplant Congress
Outcome Predictors with Perioperative Kidney Transplant Midodrine Usage
R. Watson¹, S. Mullins², S. Williams³, F. Fakhre⁴, K. Robichaux⁴, S. Mohammed⁴, M. Gosselin³, A. Kumar⁵, J. Buggs¹, V. Bowers¹
¹Transplant Surgery, Tampa General Hospital, Tampa, FL, ²Florida A &M University, Tallahassee, FL, ³University of Tampa, Tampa, FL, ⁴University of South Florida, Tampa, FL, ⁵Morsani College of Medicine, University of South Florida, Tampa, FL
*Purpose: Midodrine is an alpha-1 agonist drug commonly used to aid hypotension in kidney transplant patients. Little is described regarding outcomes with midodrine in kidney…
2022 American Transplant Congress
The Roles of Intrarenal B Cells in Regulating Antibody Mediated Rejection After Kidney Transplantation
H. Zhang¹, C. Cavazzoni¹, E. Bechu¹, B. Hanson¹, M. A. Podestà¹, D. Kreisel², A. Alessandrini³, P. Sage¹
¹Transplantation Research Center, Renal Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, ²Department of Surgery, Washington University in St Louis, St. Louis, MO, ³Center for Transplantation Sciences, Department of Surgery, Massachusetts General Hospital, Harvard, Boston, MA
*Purpose: Alloimmune rejection after kidney transplantation is associated with substantial infiltration of immune cells such as T and B cells in transplanted grafts. However, the…
2022 American Transplant Congress
Impact of Late and Recurrent Acute Graft Pyelonephritis on Long-Term Kidney Graft Outcomes
M. Pacaud¹, L. Colas¹, C. Kerleau², F. Le Borgne³, M. Giral², S. Brouard¹, J. Dantal²
¹CRT2I, Université de Nantes, Nantes, France, ²Service de Néphrologie et immunologie clinique, CHU de Nantes, Nantes, France, ³INSERM UMR 1246-SPHERE, Université de Nantes, Nantes, France
*Purpose: While Urinary tract infections are the most common infections in kidney transplant recipients, the impact of late acute graft pyelonephritis (AGPN) on graft outcomes…
2022 American Transplant Congress
Quality of Life of Brazilian Kidney Transplant Patients: A Sub-Project of ADHERE Brazil Multicenter Study
A. R. Almeida¹, F. R. Grincenkov², F. A. Colugnati¹, J. O. Medina³, S. De Geest⁴, H. Sanders-Pinheiro¹, S. ADHERE BRAZIL¹
¹Nephrology, Federal University of Juiz de Fora, Juiz de Fora, Brazil, ²Psychology, Federal University of Juiz de Fora, Juiz de Fora, Brazil, ³Nephrology, Hospital do Rim. Federal University of São Paulo, São Paulo, Brazil, ⁴Department of Public Health, Institute of Nursing Science, Basel, Switzerland
*Purpose: While the quality of life (QoL) is known to improve after kidney transplant (KT), epidemiologic data are limited in Brazil. We aimed to describe…
2022 American Transplant Congress
Use of Everolimus and Reduced Calcineurin Inhibitors in Bk Nephropathy: Insights from Follow-Up and Surveillance Biopsies
Z. S. Zaky, M. Spinner, B. Stephany
Cleveland Clinic, Cleveland, OH
*Purpose: BK virus-associated nephropathy (BKVAN) is a clinically important entity that results in an allograft loss in kidney transplant recipients (KTRs). Mammalian target of rapamycin…
2022 American Transplant Congress
Assessment of Circulating B Cell Developmental Stages Early After Kidney Transplantation. Preliminary Data from a Single Center
A. Fouza¹, A. Fylaktou², A. Xohelli², E. Sampani³, B. Nikolaidou², D. Asouhidou², N. Antoniadis¹, E. Kasimatis³, M. Stangou³, G. Tsoulfas¹, A. Papagianni³
¹Division of Transplantation, Department of Surgery, Aristotle University of Thessaloniki, Thessaloniki, Greece, ²National Peripheral Histocompatibility Center, Immunology Department, Hippokration General Hospital of Thessaloniki, Thessaloniki, Greece, ³Department of Nephrology, Aristotle University of Thessaloniki, Thessaloniki, Greece
*Purpose: B lymphocytes (BL) is an important immune component in the function of kidney transplants, through antibody production, antigen-presentation to T cells, secretion of cytokines,…
2022 American Transplant Congress
BK Polyomavirus Infection is Not Associated with a Meaningful Increase in Donor-Derived Cell-Free DNA
J. Fisher¹, K. Vieira¹, R. Burke², R. Gohh¹, R. Rogers¹
¹Warren Alpert Medical School of Brown University, Providence, RI, ²CareDx, Brisbane, CA
*Purpose: Donor-derived cell-free DNA (dd-cfDNA) is a non-invasive measure of early allograft injury that has been clinically validated as a surveillance tool to detect antibody…
2022 American Transplant Congress
Factors Linked with Evaluation to Wait Listing for Referred Patients at the University of Texas Medical Branch’s Main Center and Outreach Clinic – A Step Towards Kidney Transplantation
A. Rizvi¹, M. Mujtaba², S. Hussain³, J. Fair⁴, M. Kueht⁴, A. Gamilla-Crudo⁵
¹Internal Medicine, Nephrology, University of Texas Medical Branch, Galveston, TX, ²University of Texas Medical Branch, Galveston, TX, ³University of Texas Medical Branch, Houston, TX, ⁴Surgery, University of Texas Medical Branch, Galveston, TX, ⁵University of Texas Medical Branch, League City, TX
*Purpose: Numerous factors can be associated with transplant candidates’ placement on the wait list. We herein set forth to assess patient characteristics and factors associated…
2022 American Transplant Congress
Evaluation of Genotype Based Clustering Method of Single-Cell RNA-Sequencing Data from Human Kidney Allograft Biopsies
G. Thareja¹, A. Belkadi¹, S. Rahim², H. Yang², F. B. Mueller², K. Suhre¹, M. Suthanthiran², T. Muthukumar²
¹Weill Cornell Medicine, Doha, Qatar, ²Weill Cornell Medicine, New York, NY
*Purpose: Single-cell RNA sequencing (scRNA-seq) characterizes expression profiles of individual cells, providing novel insights into new cell types or new cell states that were not…
2022 American Transplant Congress
Resistance Isn’t Futile: The Independent Effect of Pumping Resistance on Long-Term Kidney Graft Survival
D. Stewart¹, J. Foutz¹, L. Kamal², G. Gupta²
¹United Network for Organ Sharing, Richmond, VA, ²Virginia Commonwealth University Health, Richmond, VA
*Purpose: Kidneys are pumped for therapeutic (to mitigate deleterious effects of ischemia), practical (to facilitate transplant scheduling), and prognostic (to assess organ quality) purposes. Yet…