Articles tagged "Kidney transplantation"

2022 American Transplant Congress
Area Deprivation Index is Associated with Worse Patient Survival Following Adult Kidney Transplantation
J. Hendele¹, J. Perkins², J. Nichols³, A. Dick⁴
¹Division of Transplant Surgery, Department of Surgery, University of Washington, Seattle, WA, ²Clinical and Bio-Analytics Transplant Laboratory (CBATL), University of Washington, Seattle, WA, ³University of Washington School of Medicine, Seattle, WA, ⁴University of Washington School of Medicine Seattle, Seattle, WA
*Purpose: Area Deprivation Index (ADI) has been utilized as a granular measure of local socioeconomic status for nearly two decades. This study is the first…
2022 American Transplant Congress
Study Of Matrix Metalloproteinase (mmp) And Tissue Inhibitors Of Metalloproteinase (timp) Gene Polymorphisms In Renal Allograft Outcome
J. P. Tom¹, J. Singh¹, A. Sharma², R. Aggarwal¹, R. Nada³, R. Ramachandran⁴, S. Anand¹, R. Minz¹
¹Department of Immunopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India, ²Department of Renal Transplant Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, India, ³Department of Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India, ⁴Department of Nephrology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
*Purpose: Our study aimed to find a role, if any, of functional gene polymorphisms of MMP and their inhibitors- TIMP in renal allograft outcome.*Methods: The…
2022 American Transplant Congress
Outcome of Kidney Transplantation in the Elderly Compared with Dialysis
B. Shi¹, T. Ying², S. Chadban²
¹University of Sydney, Camperdown, Australia, ²Royal Prince Alfred Hospital, Camperdown, Australia
*Purpose: Although kidney transplantation offers improved survival and quality of life compared to remaining on dialysis for most recipients, outcomes for elderly patients (older than…
2022 American Transplant Congress
Beyond CPRA: Identifying Sensitized Kidney Candidates with Markedly Low Access to Transplant
K. Bradbrook¹, A. Maldonado², K. Sjöholm², C. Kjellman², J. Lee³, D. Stewart¹
¹UNOS, Richmond, VA, ²Hansa Biopharma AB, Lund, Sweden, ³Immucor, Norcross, GA
*Purpose: The Kidney Allocation System (KAS) improved the rates of transplantation in highly sensitized (HS) patients. However, a subset of HS patients remain at a…
2022 American Transplant Congress
Computer vs Human-Based Prediction and Stratification of the Risk of Long-Term Kidney Allograft Failure
G. Divard¹, M. Raynaud¹, V. Tataputii², B. Abdalla³, C. Legendre¹, C. Lefaucheur¹, O. Aubert¹, A. Loupy¹
¹Paris Transplant Group, Paris, France, ²NYU Langone Health, New York, NY, ³UCLA, Los Angeles, CA
*Purpose: Clinical decision-making process after transplantation is mainly driven by patient individual risk of allograft failure prediction assessed by physicians. However, this task remains difficult…
2022 American Transplant Congress
Impact of Cytomegalovirus and BK Virus Infection on Clinical Outcomes in Kidney Transplant Recipients
W. Park, J. Yang, J. Kwon, J. Lim, Y. Kim, J. Paek, K. Jin, S. Han
Division of Nephrology, Department of Internal Medicine, Keimyung University School of Medicine, Keimyung University Dongsan Hospital, Daegu, Korea, Republic of
*Purpose: Cytomegalovirus (CMV) or BK virus (BKV) infection is one of the important opportunistic infections in kidney transplant recipients (KTRs). CMV or BKV infection can…
2022 American Transplant Congress
Laparoscopic Kidney Transplantation : A Lost Art ?
F. J. Osella¹, I. Cabrera¹, J. Walther², L. Leon², O. Guardia², M. Rial²
¹Surgery - Kidney and Pancreas Trasplant, ITAC by Diaverum, Buenos Aires, Argentina, ²Nephrology, ITAC by Diaverum, Buenos Aires, Argentina
*Purpose: Laparoscopic surgery and currently robot-assisted surgery have transformed the current surgery paradigm, showing a lower systemic inflammatory response, less post-operative pain, smaller incisions, shorter…
2022 American Transplant Congress
Outcomes of Transplants in Kidneys with Multiple Arteries
C. Seet, L. Clementoni, I. H. Mohamed, M. A. Khurram
The Royal London Hospital, London, United Kingdom
*Purpose: Variations in kidney anatomy, such as the presence of multiple arteries, may affect decisions regarding implantation. A significant proportion of living donor and some…
2022 American Transplant Congress
Defining New Arterial and Arteriolar Lesions Accompanying Transplant Glomerulopathy: Potential Additions to the Histologic Assessment of ABMR
A. Perkowska-Ptasinska¹, D. Deborska-Materkowska², M. Ciszek³, M. Myslak⁴, J. Chang⁵, J. Reeve⁶, P. Halloran⁷
¹Pathology, Medical University of Warsaw, Warsaw, Poland, ²Transplantation Medicine, Nephrology and Internal Diseases, Medical University of Warsaw, Warsaw, Poland, ³Immunology, Transplantation Medicine and Internal Diseases, Medical University of Warsaw, Warsaw, Poland, ⁴Infectious Diseases, Hepatology and Liver Transplantation, Pomeranian Medical University, Szczecin, Poland, ⁵Alberta Transplant Applied Genomics Center, Edmonton, AB, Canada, ⁶Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, ⁷Pathology, Alberta Transplant Applied Genomics Centre, University of Alberta, Edmonton, AB, Canada
*Purpose: Transplant glomerulopathy (TG) results from chronic endothelial injury most commonly related to ABMR. Surprisingly, except for PTC, the relation between TG and other vascular…
2022 American Transplant Congress
Evs from Patients with Amr Induce Tubular Senescence and Endmt Through Horizontal Transfer of Mirnas
R. Franzin¹, A. Stasi¹, F. Sallustio¹, S. Bruno², G. Merlotti³, M. Quaglia³, G. Grandaliano⁴, P. Pontrelli¹, J. Thurman⁵, G. Camussi², G. Stallone⁶, V. Cantaluppi³, L. Gesualdo¹, G. Castellano⁷
¹DETO, University of Bari, Bari, Italy, ²University of Turin, Turin, Italy, ³University of Piemonte Orientale, Novara, Italy, ⁴Università Cattolica Sacro Cuore, Rome, Italy, ⁵University of Colorado School of Medicine, Aurora, CO, ⁶University of Foggia, Foggia, Italy, ⁷University of Milan, Milan, Italy
*Purpose: Extracellular vesicles (EV) are emerging mediators in several diseases; however, their role in antibody-mediated allograft rejection (AMR) has been poorly investigated.*Methods: Plasma EVs from…