Articles tagged "Kidney transplantation"

2017 American Transplant Congress
SIRPα⁺ DCs and the Time-Dependent CD4⁺CD8⁺ Double Positive T Cell Infiltration in Accepted Renal Allografts.
T. Ashry,^1,2 C. Yang,² B. Jiang,² D. Ndishabandi,² P. Russel,^1,2 R. Colvin,^1,2 J. Madsen,^1,2 A. Alessandrini.^1,2
¹HMS, Boston; ²MGH, Boston
IntroductionIn 2015 Overgaard and colleagues proposed that double positive T (DPT) cells, usually unique to the thymus, represent more than a developmental phase as extrathymic…
2017 American Transplant Congress
Biopsies (Bx) of Renal Allografts with Antibody- + Cell-Mediated Rejection (ABMR/CMR) Exhibit Gene Expression Signatures from Both Types of Rejection.
H. Zhang,¹ C. Nast,² J. Doldron,² M. Cheung,² J. Mirocha,³ J. Kahwaji,¹ A. Vo,¹ S. Jordan,¹ M. Toyoda.¹
¹Transplant Immunology Laboratory, Cedars-Sinai Medical Center, Los Angeles; ²Pathology, Cedars-Sinai Medical Center, Los Angeles; ³Biostatistics Center, Cedars-Sinai Medical Center, Los Angeles
Background: In HLA-sensitized kidney transplant patients (Pts) the concomitant presence of ABMR/CMR on Bx is associated with a more severe and (&) usually irreversible injury…
2017 American Transplant Congress
Outcome and Risk Factors of Recurrent Focal Segmental Glomerulosclerosis After Kidney Transplantation.
G. Chen, C. Wang, Z. Wu, J. Zhang, S. Yu, C. Wang, J. Qiu, L. Chen.
Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
Background Recurrent focal segmental glomerulosclerosis(FSGS) is common after kidney transplantation . We conducted a retrospective cohort study with the aim to investigating the long-term outcome…
2017 American Transplant Congress
A Phase Ib, Open Label, Single Arm Study to Assess the Safety, Pharmacokinetics, and Impact on Humoral Sensitization of SANGUINATE Infusion in Patients with End-Stage Renal Disease.
B. Abu Jawdeh,¹ E. Woodle,¹ A. Leino,¹ T. Dorst,¹ M. Abdallah,¹ A. Govil,¹ D. Byczkowski,² H. Misra,² A. Abuchowski,² R. Alloway.¹
¹U.Cincinnati, OH; ²Prolong Pharmaceuticals, NJ
Purpose:The endeavor and resources spent to study desensitization haven't been matched by an effort to investigate strategies to prevent sensitization.The purpose of this study was…
2017 American Transplant Congress
Induction Treatment with Rabbit Antithymocyte Globulin versus Basiliximab in Renal Transplant Recipients with Planned Early Steroid Withdrawal.
S. Gabardi.
Transplant Surgery, Brigham and Women's Hospital, Boston
Introduction: In a previous study by our group, rabbit antithymocyte globulin (r-ATG) induction was associated with lower rates of rejection when compared to basiliximab in…
2017 American Transplant Congress
Impact of Serum EDTA Treatment on Identification of Unacceptable Antigens for Kidney Transplant Candidates.
J. Xin, N. Brown, R. Upchurch, J. Weidner, S. Marino.
Pathology, University of Chicago Medicine, Chicago, IL
BACKGROUND AND AIMS: The prozone effect is one factor causing false negative reactions in HLA antibody testing. EDTA, which is commonly used to remove this…
2017 American Transplant Congress
ABO Incompatible Deceased Donor Renal Transplantation: Exploring the Possibilities.
M. Sypek,^1,2 R. Masterson,^1,2 P. Hughes.^1,2
¹Dept of Nephrology, Royal Melbourne Hospital, Melbourne, Australia; ²University of Melbourne, Melbourne, Australia
Background: There is significant variation in waiting times for deceased donor (DD) renal transplants based on recipient blood group. Furthermore, there is an increased discard…
2017 American Transplant Congress
Telemedicine Utilization After Kidney Transplantation Was Not Associated with Decreased Early Hospital Readmission Rate.
N. Elfadawy, E. Sanchez, K. Woodside, J. Augustine, D. Hricik, N. Sarabu.
Kidney Transplantation, University Hospitals Cleveland Medical Center, Cleveland, OH
Kidney transplant population has marked high 30-day early hospital readmission (EHR) rate. EHR has attracted considerable attention recently as an acceptable metric of poor hospital…
2017 American Transplant Congress
Renal Function, Albuminuria, and the Risk of Death and Graft Loss After Kidney Transplantation.
N. Lam,¹ M. Tonelli,² K. Lentine,³ B. Hemmelgarn,² F. Ye,¹ K. Wen,¹ S. Klarenbach.¹
¹University of Alberta, Edmonton, Canada; ²University of Calgary, Calgary, Canada; ³Saint Louis University, St. Louis
In 2012, the KDIGO guidelines updated the classification system for chronic kidney disease to include albuminuria. Whether this classification system prognosticates adverse clinical outcomes among…
2017 American Transplant Congress
Early Outcomes of Kidney Transplantation When Comparing Waist-to-Hip Ratio vs. Body Mass Index.
R. Patankar,¹ A. Gamilla-Crudo,¹ K. Gugliuzza,² O. Salim,³ S. Shah,¹ F. Ikram,⁴ M. Mujtaba.¹
¹Division of Nephrology and Hypertension, University of Texas Medical Branch, Galveston, TX; ²Department of Surgery, University of Texas Medical Branch, Galveston, TX; ³Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX; ⁴University of Texas Medical Branch, Galveston, TX
Introduction - High body mass index (BMI) is a concern for kidney transplantation due to wound infections and other surgical complications. BMI has been used…