2017 American Transplant Congress
The Search for a Polyomavirus BK Nephropathy (BKPyVN)-Specific Transcriptomic Signature.
Recent work suggests that genes related to DNA replication signaling, RNA polymerase assembly, & pathogen recognition receptors are biomarkers for BKPyVN (Sigdel et al. Transplant…2017 American Transplant Congress
Evaluation of Immunological States of Patients with Cytomegalovirus Infection After Kidney Transplantation.
Department of Gastroenterological and Transplant Surgery, Hiroshima University, Hiroshima, Japan
Background: Generally, it is thought that strong immunosuppression causes cytomegalovirus (CMV) infection after kidney transplantation (KT); thus, physicians often reduce the dose of the immunosuppressant…2017 American Transplant Congress
Generation of Autologous CMV and EBV-Specific T-Cell Lines from Seronegative Patients for Cell Therapy of Opportunistic Infections Following Kidney Transplantation.
Cytomegalovirus (CMV) and Epstein-Barr virus (EBV) reactivations after kidney transplant are associated with substantial morbidity, especially in seronegative patients. Adoptive immunotherapy using virus-specific T cells…2017 American Transplant Congress
Integrative Analysis of ExomeSeq and Gene Expression Data for Identification of Novel Variants Associated with Antibody-Mediated Rejection in Kidney Transplant.
Background: The objective of this work is to characterize the impact of the donor-recipient (D/R) HLA and non-HLA mismatches on the risk of antibody-mediated rejection…2017 American Transplant Congress
Incidence of Fungal and Viral Infections Following Rituximab Use in Kidney Transplant Recipients.
Northwestern Memorial Hospital, Chicago, IL
Rituximab is used off-label in solid organ transplant for desensitization and treatment of antibody-mediated rejection (AMR). It targets CD20 and results in B cell depletion.…2017 American Transplant Congress
Healthcare Resource Utilization for Patients with Donor-Specific Antibodies Post-Kidney Transplantation.
Formation of de novo donor-specific antibodies (dnDSA) against human leukocyte antigens (HLA) contributes to inferior kidney transplant (KT) outcomes. No data exist on healthcare resource…2017 American Transplant Congress
Understanding the Role of Induction Agents in Older versus Younger Kidney Transplant Recipients.
Johns Hopkins University, Baltimore, MD
Background: There has been an increase in the number of older (over 65) KT recipients. Aging-related changes such as differences in immune senescence may influence…2017 American Transplant Congress
Triptolide Alleviating Acute Antibody Mediated Rejection by Inhibition of B Cell Activation in Presensitized Recipients.
Backgroud: Acute antibody mediated rejection (AMR), resistant to most anti-rejection therapy, is main cause for renal graft loss. Triptolide(TPL) had been reported as a promising…2017 American Transplant Congress
Kidney Transplantation Outcomes from Donors with Acute Kidney Injury.
Abdominal Transplant Surgery, Montefiore Medical Center, Bronx, NY
Background- Organ scarcity and increased waiting times for kidney transplantation has led the transplant community to utilize more sub-optimal organs while continuing providing survival benefit…2017 American Transplant Congress
Increasing Living Donation by Implementing the Kidney Coach Program.
Recanati Miller Transplantation Institute, Mount Sinai Hospital, New York, NY
Introduction: It is firmly established that for patients requiring transplant, living donor kidney transplantation (LDKT) is better than deceased donor transplantation. However, recipients find it…
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