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Articles tagged "Kidney transplantation"

  • 2017 American Transplant Congress

    Global Kidney Exchange.

    M. Rees,1 T. Dunn,2 S. Rees,3 J. Rogers,4 A. Roth,5 C. Kuhr,6 O. Ekwenna,1 K. Krawiec,7 S. Jain,1 C. Marsh,8 P. Sindhwani,1 M. Zimmerman,9 R. Forbes,10 M. Tan,11 I. Ashlagi,5 R. Correa-Rotter,12 S. Paloyo.13

    1U Toledo, Toledo, OH; 2U Minn, Minneapolis, MN; 3APD, Perrysburg, OH; 4Wake Forrest U, Winston Salem, NC; 5Stanford U, Palo Alto, CA; 6Virginia Mason, Seattle, WA; 7Duke U, Durham, NC; 8Scripps Green Hosp, La Jolla, CA; 9Froedtert Hosp, Milwaukee, WI; 10Vanderbilt U, Nashville, TN; 11Piedmont Hosp, Atlanta, GA; 12INCMNSZ, Mexico City, Mexico; 13St Luke's Hosp, Manila, Philippines

    Introduction: Innovative solutions are required to overcome the organ shortage.Methods: The cost differential between dialysis and transplantation in some countries allows the exchange of kidneys…
  • 2017 American Transplant Congress

    BK Virus, Cytomegalovirus and Epstein-Barr Virus Reactivation in Renal Transplant Patients: Results from a Large Multicenter Study.

    A. Blázquez-Navarro,1 C. Dang-Heine,1 M. Or-Guil,2 C. Bauer,3 T. Westoff,4 C. Hugo,5 P. Reinke,1 B. Sawitzki,1 N. Babel.1,4

    1Berlin-Brandenburg Center for Regenerative Therapies, Berlin, Germany; 2Humboldt-Universität zu Berlin, Berlin, Germany; 3MicroDiscovery GmbH, Berlin, Germany; 4Medizinische Klinik I, Universitätsklinikum der Ruhr-Universität Bochum, Herne, Germany; 5Medizinische Klinik III, Universitätsklinikum Carl Gustav Carus, Dresden, Germany

    The purpose of this study was to ascertain the prevalence and clinical implications of three of the most relevant opportunistic infections in kidney transplantation, namely…
  • 2017 American Transplant Congress

    Longitudinal Study of Donor Specific Antibodies in a Pediatric Kidney Transplant Population; Response to Optimization of Anti-Proliferative Therapy.

    A. Rounds, M. Moss, M. Bock, J. Goebel.

    Children's Hospital Colorado, Aurora, CO

    In 2015 we implemented surveillance donor-specific antibody (DSA) monitoring in our pediatric kidney transplant recipients (pKTR); we found that in stable pKTRs (i.e. no changes…
  • 2017 American Transplant Congress

    Even with National Sharing, the Prospects of a 100% Sensitized Patient Receiving a Transplant Vary Dramatically Depending on the Precise CPRA Value.

    D. Stewart,1 A. Kucheryavaya,1 D. Tyan,2 H. Gebel,3 R. Bray,3 N. Turgeon.3

    1UNOS, Richmond, VA; 2Stanford Univ, Palo Alto, CA; 3Emory Univ Hosp, Atlanta, GA

    Background: In the Kidney Allocation System (KAS), CPRA of 99% & 100% candidates receive regional and national priority. This broader sharing, along with adoption of…
  • 2017 American Transplant Congress

    Multiple Dosing of Anti-C1s Antibody TNT009 – Effect on HLA Antibody-Triggered Complement Activation in Healthy Volunteers and Kidney Transplant Recipients with Antibody-Mediated Rejection.

    J. Muhlbacher,1 B. Jilma,2 M. Wahrmann,3 F. Eskandary,3 J. Gilbert,4 S. Panicker,4 G. Böhmig.3

    1Department of Surgery, Medical University Vienna, Vienna, Austria; 2Department of Clinical Pharmacology, Medical University Vienna, Vienna, Austria; 3Department of Medicine III, Medical University Vienna, Vienna, Austria; 4True North Therapeutics, Inc., San Francisco, CA

    Study purpose. Complement inhibition may be an attractive strategy to prevent antibody-mediated allograft injury. One promising therapeutic target may be the enzymatic activity of key…
  • 2017 American Transplant Congress

    Emergency Department Utilization Among Kidney Transplant Recipients in the United States.

    B. Lovasik, R. Zhang, J. Schrager, S. Pastan, A. Adams, R. Patzer.

    Emory University, Atlanta, GA

    Background:Single center studies suggest that kidney transplant (KTx) recipients have a high rate of emergency department (ED) utilization, and ED visits are associated with graft…
  • 2017 American Transplant Congress

    Is “Death with a Functioning Graft (DWF)” Really Death with Function? Data from the Long-Term Deterioration of Kidney Allograft Function (DeKAF) Study.

    R. Gaston,1 A. Fieberg,2 L. Hunsicker,3 D. Rush,4 R. Leduc,2 J. Connett,2 A. Matas,2 DeKaf Investigators.

    1UAB, Birmingham, AL; 2U Minnesota, Minneapolis, MN; 3U Iowa, Iowa City, IA; 4U Manitoba, Winnipeg, Canada

    To understand causes of kidney transplant (KT) failure, outcomes are often segregated into death-censored graft failure (DCGF, a proxy for immunologic injury) and DWF. To…
  • 2017 American Transplant Congress

    Generation of Natural Antibodies Post Transplant and Association with Kidney Allograft Loss.

    S. See,1 A. Loupy,2 O. Aubert,2 Y. Veras,1 X. Lebreton,2 B. Gao,3 C. Legendre,2 D. Anglicheau,2 E. Zorn.1

    1Columbia Center for Translational Immunology, Columbia University Medical Center, New York, NY; 2Department of Kidney Transplantation, Hopital Necker, Université Paris, René Descartes and APHP, Paris, France; 3The First Hospital of Jilin University, Changchun, China

    The development of donor specific antibodies (DSA) reacting to mismatched donor class I and class II HLA is a prominent risk factor for kidney graft…
  • 2017 American Transplant Congress

    HOPE Act – The First Year.

    A. Wilk, S. Taranto, R. Urban, D. Klassen.

    United Network for Organ Sharing, Richmond, VA

    Background: The HIV Organ Policy Equity (HOPE) Act, enacted on 11/21/13, allows for research on transplants of kidneys (KI) or livers (LI) from HIV+ donors…
  • 2017 American Transplant Congress

    A Dedicated Young Adult Service with a Youth Worker Increases Engagement of Teenagers and Young Adults with Kidney Transplantation and Impacts Favourably on Clinical Outcomes.

    D. Cross, P. Harden.

    Oxford Transplant Centre, Oxford University Hospital NHS Foundation Trust, Oxford, United Kingdom

    Transition from pediatric to adult care is associated with a high risk of transplant loss, increased morbidity and mortality. Frequently there is poor engagement by…
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