2017 American Transplant Congress
C3d-Binding Anti-DQ DSA Is Associated with a High Risk for Late ABMR and Graft Failure in Stable Kidney Transplant Recipients.
Introduction:Donor specific anti-HLA antibodies (DSA) are a major cause of antibody-mediated rejection (ABMR) and poor graft outcome in kidney transplant recipients (KTR). Critical issue is…2017 American Transplant Congress
The American Transplant Congress Effect on Kidney Discard Rates in the United States.
1Mayo Clinic, Scottsdale, AZ; 2University of Utah, Salt Lake City, UT
Background: Deceased-donor kidneys with high kidney donor risk index (KDRI) are often discarded despite evidence that certain candidates would have better survival accepting these kidneys…2017 American Transplant Congress
Intended and Unexpected Impact of the New Kidney Allocation System on a Large Volume Transplant Program.
University of California Davis, Sacramento, CA
On December 4, 2014 the new Kidney Allocation System (KAS) went into effect in the United States. The intentions of KAS were to increase the…2017 American Transplant Congress
Clinically Relevant Immunosuppression Promotes MCMV Reactivation and Dissemination Following Transplantation of Latently Infected Kidneys.
Reactivation of latent Cytomegalovirus (CMV) is an important problem facing clinical transplantation. We have previously described a model for murine CMV (MCMV) reactivation following kidney…2017 American Transplant Congress
Donor Derived and BK Virus Positive Urologic Cancers After Renal Transplantation.
Background. Donor-derived tumours in organ recipients develop from donor tissue with no known pre-existing malignancy in the donor. In addition, polyoma BK virus (BKV) might…2017 American Transplant Congress
Neutropenia in Kidney and Liver Transplant Recipients: Risk Factors and Consequences.
Aim: This study aimed to: 1) Define the risk factors associated with neutropenia within the first year post kidney or liver transplantation; 2) Describe the…2017 American Transplant Congress
Retroactive Application of a New Risk Index for Living Donor Kidney Transplantation (LKDPI) to Renal Transplants in Veracruz, Mexico.
Kidney Donor Profile Index (KDPI) was designed to estimate the graft loss risk in deceased donor transplants. Recently, the Epidemiology Research Group for Organ Transplantation…2017 American Transplant Congress
Kidney Transplantation in HCV+ Recipients in a New Era of Diagnostics and Therapeutics.
Duke University Medical Center, Durham, NC
BackgroundHepatitis-C infected persons (HCV+) evaluated for kidney transplantation receive rigorous staging of their liver disease, often including liver biopsy. Meanwhile, studies have shown that despite…2017 American Transplant Congress
Vimentin Regulates ß-Catenin Translocation During Epithelial to Mesenchymal Transition in Renal Fibrosis.
Sugery, Section of Transplantation, Albany Medical Center, Albany, NY
Introduction: Most renal transplants ultimately fail secondary to chronic allograft nephropathy (CAN). The development of Epithelial to Mesenchymal Transition (EMT) in renal tubular epithelial cells…2017 American Transplant Congress
C-C Chemokine Receptor 5 Polymorphisms and Risk of Antibody-Mediated Rejection in Renal Transplantation.
Antibody-mediated rejection (AMR) is the leading cause of graft failure after kidney transplantation. C-C Chemokine receptor 5 (CCR5) plays an important role in immune cell…
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