Articles tagged "Kidney transplantation"

2018 American Transplant Congress
Urinary C-X-C Motif Chemokines 13 is a Noninvasive Biomarker of Antibody-Mediated Renal Allograft Rejection
D. Chen, J. Chen.
Kidney Disease Center, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Background: Since acute rejection remains one of the major complications which necessitate periodic surveillance, noninvasive diagnostic/prognostic methods are preferred by renal transplant recipients. Here we…
2018 American Transplant Congress
Impact of Pretransplant Donor-Specific Antibodies on Kidney Allograft Recipients with Negative Flow Cytometry Crossmatches
H. Kwon, Y. Kim, J. Choi, S. Shin, J. Jung, M. Cho, J. Kim, D. Han.
Asan Medical Center, Seoul, Korea.
This study evaluated the impact of DSA on clinical outcomes in KT recipients negative on FCXM. Of 575 consecutive patients who underwent living donor KT…
2018 American Transplant Congress
Efficacy of IVIG + Rituximab Desensitization Therapy on HLA Antibodies is Independent of HLA Loci
X. Zhang,¹ S. Jordan.²
¹HLA and Immunogenetics Laboratory, Comprehensive Transplant Center/ Cedars-Sinai Health Systems, Los Angeles, CA; ²Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.
Aim: Desensitization with the intravenous immunoglobulin (IVIG) and Rituximab therapy is commonly used to promote transplant of highly sensitized patients. It is suggested that HLA-DQ…
2018 American Transplant Congress
Fosfomycin vs Other Antibiotics for UTI after Kidney Transplant
O. Mgbako,¹ J-.E. Ha,¹ N. Topilow,² E. Min,¹ D. Taupin,¹ V. Tatapudi,¹ B. Gelb,¹ S. Hochman.¹
¹NYU Langone Health, New York; ²Mt Sinai West, New York.
Urinary tract infection (UTI) is a frequent infectious complication in kidney transplant recipients (KTRs). Antibiotic resistance is common among urine bacterial isolates in this population.…
2018 American Transplant Congress
Early Infectious Outcomes of Older Adults Undergoing Kidney Transplantation (KT). A Case Control Study
M. Hemmersbach-Miller,^1,2 K. Schmader.³
¹Infectious Diseases, Duke University Medical Center, Durham, NC; ²Duke Clinical Research Institute, Durham, NC; ³Geriatrics, Duke University Medical Center, Durham, NC.
Study Purpose: Our aim was to investigate if among older KT recipient, the types of infections, number of rejections, graft and patient survival in the…
2018 American Transplant Congress
The Impact of Immunosuppression on Mineral Metabolism One Year after Kidney Transplantation: Differences between a Mycophenolate-Based Regimen versus an mTOR-Inhibitor-Based One
D. Cucchiari,¹ S. Karam,² P. Ventura-Aguiar,¹ F. Diekmann,¹ J. Torregrosa.¹
¹Renal Transplant Unit, Hospital Clinic, Barcelona, Spain; ²Department of Medicine, Saint George Hospital University Medical Center, Beirut, Lebanon.
INTRODUCTION: after kidney transplantation, a substantial amount of patients still suffer from Mineral Bone Disorder. The role of different immunosuppressive therapies on mineral metabolism in…
2018 American Transplant Congress
The Price of Diabetes Medication Management in Kidney Transplantation: Similar Rates of Readmissions, but More Healthcare Utilization
J. Hardcopf, H. Meadows, N. Pilch, C. Perez, N. Patel, J. Fleming, H. Corbo, T. Harrison, B. O'Brien, D. DuBay, D. Taber.
Medical University of South Carolina, Charleston, SC.
Background: The aim of this study was to determine whether changing diabetes (DM) medications during the index admission for kidney transplant (KT) is significantly associated…
2018 American Transplant Congress
Challenges in Cultural and Linguistic Discordance in Caring for Somali Kidney Transplant Recipients at a Large-Volume Transplant Center
K. Peterson,¹ O. Serrano,¹ M. Odegard,¹ S. Mongin,² D. Berglund,³ D. Vock,⁴ S. Chinnakotla,¹ T. Dunn,¹ E. Finger,¹ R. Kandaswamy,¹ T. Pruett,¹ A. Matas.¹
¹Division of Transplantation, Department of Surgery, University of Minnesota, Minneapolis, MN; ²Biostatistical Design and Analysis Center, Clinical and Translational Science Institute, University of Minnesota, Minneapolis, MN; ³Informatics Services for Research and Reporting, Fairview Health Services, Minneapolis, MN; ⁴Division of Biostatistics, University of Minnesota, Minneapolis, MN.
OBJECTIVE: Kidney Transplantation (KT) demands navigation of a complex healthcare system and adherence to lifelong immunosuppression therapy. Cultural and linguistic discordance between patients and providers…
2018 American Transplant Congress
Improved Mouse Renal Transplantation Model Mimicking Clinical Antibody Mediated Rejection
D. Zhao,¹ T. Liao,¹ S. Li,¹ J. Zhou,² F. Han,¹ Y. Dong,³ Q. Sun.¹
¹Organ Transplantation Institution, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China; ²Department of Pathology, Third Affiliated Hospital of Sun Yat-sen University, Guanghzou, Guangdong, China; ³Department of Pathology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Antibody mediated rejection (AMR) is main barrier to long term renal graft survival and mouse model is important to understand the mechanisms of AMR and…
2018 American Transplant Congress
Non-Immunologic Pairing of Kidney Transplant Donors and Recipients: How Important is HLA Match Status?
A. Miller, B. Kiberd, K. Tennankore.
Division of Nephrology, Department of Medicine, Dalhousie University, Halifax, NS, Canada.
Currently, allocation preference in deceased donor kidney transplantation is given to donors and recipients (D/R) with 0 human leukocyte antigen (HLA) mismatches (MM), with non-immunologic…