2018 American Transplant Congress
Targeting Plasma Cells with Anti-CD38mAb (Daratumumab) and CXCR4 Antagonist (Plerixafor) for Desensitization
1Surgery, Duke University, Durham, NC; 2Surgery, Mayo Clinic, Rochester, MN.
[Introduction] Sensitized patients comprise a significant portion (30%) of candidates on the transplant waiting list. Unfortunately for sensitized patients, the presence of donor-specific antibodies (DSA)…2018 American Transplant Congress
Evaluation of a Marine OXYgen Carrier (Hemo2Life®) for Organ Preservation: First Use in Kidney Transplantation in Humans
Preventing ischemia/reperfusion injuries (IRIs) is a major issue in organ transplantation. At present, grafts are preserved at 4[deg]C in preservation solution in order to reduce…2018 American Transplant Congress
Does DGF Result in Worse Outcomes in a Second Transplant?
Delayed graft function (DGF) is a risk factor for patient death, kidney allograft loss, reduced allograft function and acute rejection after kidney transplantation. Prior transplant…2018 American Transplant Congress
Pilot Study of Health IT Feasibility and Impact on Quality of Life for Young Adult Kidney Transplant Recipients
Nephrology, University of Washington, Seattle, WA.
Background: Young adult kidney transplant recipients (KTRs) are an at-risk population and long-term survival rates are significantly lower than expected. A large majority of young…2018 American Transplant Congress
Furosemide Stress Test as a Predicting Biomarker for Delayed Graft Function in Kidney Transplantation
Delayed graft function (DGF) is considered as a risk factor for long-term allograft failure and rejection episodes.There is currently no biomarker in the immediate post-kidney…2018 American Transplant Congress
Treatment of HCV Infection in Renal Transplant Recipients
Renal Transplant Unit, Instituto de Nefrologia Nephrology, Buenos Aires, Argentina.
HCV infection is associated to chronic hepatitis, cirrhosis, hepatic carcinoma and increased incidence of diabetes. Combination of new antiviral drugs have demonstrated utility in liver…2018 American Transplant Congress
Diagnostic Performance of Blood Pressure Measurement Modality in Prospective Living Kidney Donors
Nephrology, Cleveland Clinic, Cleveland, OH.
Background: Precise blood pressure (BP) measurement to exclude hypertension (HTN) is critical in evaluating living kidney donors (LKDs). 24-hour ambulatory blood pressure monitoring (ABPM) is…2018 American Transplant Congress
The Technique of Ileobladder and Kidney Transplantation in Rats and Pigs
Introduction: Small, poor compliant or unstable bladders are a major problem in patients waiting for renal transplantation (RT). The experimental technique aims to develop and…2018 American Transplant Congress
Polyclonal Cellular Immune Function is Dose-Dependently Inhibited by Immunosuppressive Drugs but Has Limited Value in Predicting Infection or Rejection Episodes
1Saarland University, Homburg/Saar, Germany; 2Saarland University, Homburg/Saar, Germany.
Background: Dosage of immunosuppressive drugs in transplant patients must be balanced to prevent graft rejection and infectious complications. Knowledge on general immune function may therefore…2018 American Transplant Congress
Inflammatory Frailty Index and Mortality after Kidney Transplantation
Frailty is a phenotype of decreased physiologic reserve and is associated with a pro-inflammatory state. Fried frailty (slow walk speed, weight loss, decreased grip, low…
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