Articles tagged "Kidney transplantation"

2018 American Transplant Congress
Inflammatory Frailty Index and Mortality after Kidney Transplantation
C. Haugen, H. Ying, M. McAdams-DeMarco, D. Segev.
Surgery, JHU, Baltimore.
Frailty is a phenotype of decreased physiologic reserve and is associated with a pro-inflammatory state. Fried frailty (slow walk speed, weight loss, decreased grip, low…
2018 American Transplant Congress
The THINKER Trial: Quality of Life Results at 6- and 12-Month Follow-Up among Hepatitis C-Negative Patients Who Received Kidney Transplants from Deceased Donors with Hepatitis C Infection
V. Potluri, D. Goldberg, A. Peter, B. Emily, B. Roy, S. Deirdre, M. Levine, J. Trofe-Clark, M. Bleicher, S. Goral, A. Sicilia, S. Nazarian, R. Reddy, P. Porrett, P. Reese.
Univ of Pennsylvania, Philadelphia, PA.
Background: Short-term (6-month) data from the first 10 subjects in the pilot THINKER-1 trial (NCT02743897; funder: Merck) suggested that kidneys from HCV-infected donors could be…
2018 American Transplant Congress
Treatment Outcomes of Recurrent Primary Focal Segmental Glomerulosclerosis (FSGS) after Kidney Transplantation
R. Aguiar,¹ F. Pereira,² A. Gasparini,³ P. Chowdhury,¹ D. Game,¹ D. Moutzouris.¹
¹Department of Nephrology and Transplantation, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom; ²Department of Renal Medicine, Hospital Dr. Fernando Fonseca, Lisbon, Portugal; ³Department of Health Sciences, University of Leicester, Leicester, United Kingdom.
Introduction: Primary FSGS can recur in the renal allograft and is associated with poor graft outcomes. There is no established therapeutic intervention to prevent or…
2018 American Transplant Congress
Assessment and Validation of Potential Predictors of Non-Adherence in Contemporary Kidney Transplant Recipients
T. Harrison, C. Perez, N. Patel, H. Meadows, J. Fleming, N. Pilch, B. O'Brien, H. Corbo, J. Hardcopf, P. Baliga, D. DuBay, D. Taber.
Medical University of South Carolina, Charleston, SC.
The aim of this study is to assess the associations between traditional proxies of medication non-adherence and graft outcomes in contemporary kidney transplant recipients (KTRs).Methods:…
2018 American Transplant Congress
The Impact of Early versus Late Clinical Outcomes on Disparities in African-American Kidney Transplant Recipients
D. Taber, J. Fleming, Z. Su, P. Mauldin, J. McGillicuddy, S. Nadig, V. Rohan, P. Baliga, D. Dubay.
MUSC, Charleston, SC.
Background: It is important to better understand the impact of early and late clinical events on disparities in African-American (AA) kidney transplant (KTX), which will…
2018 American Transplant Congress
Bortezomib in Late Antibody-Mediated Kidney Transplant Rejection – A Double-Blind Randomized Placebo-Controlled Trial (BORTEJECT Study)
F. Eskandary,¹ H. Regele,² G. Bond,¹ N. Kozakowski,² M. Wahrmann,¹ L. Hidalgo,³ H. Haslacher,⁴ C. Kaltenecker,¹ M-.B. Aretin,⁵ R. Oberbauer,¹ J. Reeve,⁶ P. Halloran,⁶ G. Böhmig.¹
¹Nephrology and Dialysis, Medical University Vienna, Viena, Austria; ²Institute of Clinical Pathology, Medical University Vienna, Vienna, Austria; ³Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB, Canada; ⁴Department of Laboratory Medicine, Medical University Vienna, Vienna, Austria; ⁵Pharmacy Department, General Hospital Vienna, AKH, Vienna, Austria; ⁶Alberta Transplant Applied Genomics Centre, University of Alberta, Edmonton, AB, Canada.
Background. Antibody-mediated rejection (ABMR) is a leading cause of long-term kidney transplant loss. Optimal treatment of late ABMR is unclear, and our current knowledge is…
2018 American Transplant Congress
Validation of a Transplant Knowledge Quiz and Its Impact on Outcomes in Kidney Transplant Recipients
H. Corbo, N. Patel, N. Pilch, V. Rohan, J. Fleming, T. Harrison, J. Hardcopf, B. O'Brien, C. Perez, P. Baliga, H. Meadows, D. Taber.
Medical University of South Carolina, Charleston.
The aim of this study is to determine if transplant quiz scores given prior to discharge were predictive of known patient risk factors and if…
2018 American Transplant Congress
Impact of Antecedent Malignancy on Kidney Transplant Outcomes: Patient, Graft, and Cancer-Free Survival
O. Serrano,¹ S. Mongin,² D. Berglund,¹ D. Vock,³ S. Chinnakotla,¹ T. Dunn,¹ E. Finger,¹ R. Kandaswamy,¹ T. Pruett,¹ A. Matas.¹
¹Surgery, University of Minnesota, Minneapolis, MN; ²Biostatistical Design and Analysis Center, Clinical and Translational Science Institute, Minneapolis, MN; ³Biostatistics, University of Minnesota, Minneapolis, MN.
OBJECTIVE: Non-skin pretransplant malignancy (NSPTM) has historically been considered a relative contraindication to kidney transplantation (KT). In addition to the conventional risk factors for cancer,…
2018 American Transplant Congress
Factor Analysis (FA) Identifies 5 Major Axes of Kidney Transplant Biopsy (KTxBx) Pathology
L. Hunsicker,¹ J. Grande,² J. Cecka,³ A. Matas,⁴ The DeKaf Consortium.
¹Int. Med., U. Iowa, Iowa City, IA; ²Pathology, Mayo Clinic, Rochester, MN; ³Immunogenetics, UCLA, Los Angeles, CA; ⁴Surgery, U. Minnesota, Minneapolis, MN.
Definitions for acute rejection (ACR) and antibody mediated rejection (AMR) in KTxBx exist, but no data driven methods exist for quantitative analysis of all Banff,…
2018 American Transplant Congress
Long Term Renal and Patient Risks for Living Kidney Donors
Y. Kim, M. Yu, Y. Kim, H. Lee.
Division of Nephrology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.
Purpose:Recent studies have issued that living kidney donor (LKD) might be exposed to higher risk for end-stage renal disease (ESRD) and death, compared with healthy…