Articles tagged "Kidney transplantation"

2018 American Transplant Congress
A Theoretical Framework to Explain Factors That Impact Completion of the Medical Evaluation Process for African American (AA) End-Stage Renal Disease (ESRD) Patient
C. Nonterah,¹ H. Gardiner,² D. Vavra.¹
¹Psychology, University of Richmond, Richmond, VA; ²Department of Social and Behavioral Sciences, Temple University, Philadelphia, PA.
Black/African Americans (B/AA) are less likely to seek kidney transplantation or complete the pre-transplant medical evaluation despite higher prevalence rates of end-stage renal disease (ESRD).…
2018 American Transplant Congress
Creatinine Monitoring by Remote Blood Spot Testing in Pediatric Kidney Transplant Recipients
J. Dickerson,¹ K. Jacot,² M. Sinkey,² J. Smith.³
¹Laboratory Medicine, Seattle Children's, Seattle; ²Transplant, Seattle Children's, Seattle; ³Pediatrics, University of Washington, Seattle.
Introduction: Pediatric kidney transplant patients are monitored frequently with laboratory testing to assess kidney transplant function and to optimize therapeutic drug levels. Challenges to timely…
2018 American Transplant Congress
Pediatric Kidney Transplant in Norway – Results after Switching from Midline to Retroperitoneal Approach in Recipients below 25 kg
R. Horneland, A. Khan, G. Steinar, T. Thorsen, M. Hagness.
Section for Transplant Surgery, Oslo University Hospital, Rikshospitalet, Oslo, Norway.
Introduction: Pediatric kidney transplants demand a high level of surgical and medical involvement and skill. In Norway, all organ transplants are centralized and performed at…
2018 American Transplant Congress
The Novel Polymer Pro-Drug APP-103 Reduces I/R Injury and Improves Graft Function in a Pre-Clinical Renal Transplant Model
K. Minami,^1,3 H. Uehara,^1,3 A. Elkhal,^1,3 A. Weins,³ S. Bae,^2,3 J. Reder,⁴ B. Houser,⁴ P. Kang,^2,3 S. Tullius.^1,3
¹Transplant Surgery Division, Department of Surgery, Brigham and Women's Hospital, Boston, MA; ²Beth Israel Deaconess Medical Center, Boston, MA; ³Harvard Medical School, Boston, MA; ⁴Celdara Medical, LLC, Lebanon, NH.
Purpose: Ischemia-reperfusion injury (IRI) is the strongest non-HLA factor that augments allogenicity of transplanted organs. Damage subsequent to IRI is critically linked to an abundance…
2018 American Transplant Congress
Patients with C-aABMR and V-Lesions in Their Renal Transplant Biopsy Have a Superior Response to Treatment
K. Sablik, M. Clahsen-van Groningen, C. Looman, M. Betjes.
Erasmus Medical Center, Rotterdam, Netherlands.
Introduction Chronic active antibody mediated rejection (c-aABMR) in the renal allograft may occur with isolated arteritis. Isolated v-lesions have been associated with an inferior graft…
2018 American Transplant Congress
Excellent Long-Term Outcomes with Kidney Transplants from Deceased Donors with Acute Kidney Injury
G. Dube, S. Husain, D. Cohen, S. Mohan.
Medicine, Columbia University Medical Center, New York, NY.
Kidney transplants (KT) from donors with acute kidney injury (AKI; terminal creatinine ≥ 2.0) are increasingly performed and have similar short-term outcomes compared with KT…
2018 American Transplant Congress
Validation of Genetic Variants Identified in GWAS for Tacrolimus Troughs
P. Jacobson,¹ D. Schladt,² W. Guan,³ J. van Setten,⁶ R. Remmel,⁴ B. Wu,³ C. Dorr,⁵ B. Keating,⁷ D. Ikle,⁹ R. Mannon,¹⁰ A. Matas,⁸ A. Israni,⁵ W. Oetting.¹
¹Experimental and Clinical Pharmacology, Univ of MN, Minneapolis, MN; ²Chronic Disease Research Group, Minneapolis Medical Research Foundation, Hennepin County Medical Center, Minneapolis, MN; ³Division of Biostatistics, Univ of MN, Minneapolis, MN; ⁴Medicinal Chemistry, Univ of MN, Minneapolis, MN; ⁵Medicine, Hennepin County Medical Center, Minneapolis, MN; ⁶Cardiology, University Medical Center Utrecht, Utrecht, Netherlands; ⁷Surgery, Univ of Pennsylvania, Philadelphia, PA; ⁸Surgery, Univ of MN, Minneapolis, MN; ⁹Rho Inc, Chapel Hill, NC; ¹⁰Department of Medicine and Surgery, Univ of Alabama, Birmingham, AL.
Purpose: Tacrolimus (TAC) is a substrate for CYP3A4/5 enzymes. It is well-known that variants in these genes are associated with variability in TAC trough concentrations.…
2018 American Transplant Congress
Transplant Cost Reduction in a Developing Country: “The Case of Guatemala”
S. Méndez,¹ B. Remey,² E. Reyes,¹ A. Aguilar-González,¹ R. Lou-Meda.¹
¹Servicio de Nefrología, Hipertensión, Diálisis y Trasplante Hospital Roosevelt/FUNDANIER, Guatemala, Guatemala; ²Department of Pharmaceutical Chemistry, Universidad del Valle de Guatemala, Guatemala, Guatemala.
Background: Guatemala, south-west of Mexico has a population of approximately 16 million people of which 60% are younger than 20 years. As any other developing…
2018 American Transplant Congress
Estimated GFR for Living Kidney Donor Evaluation before and after Donor Nephrectomy
Y. Kakuta,¹ M. Okumi,¹ R. Imamura,² N. Ichimaru,² S. Takahara,² H. Ishida,¹ K. Tanabe.¹
¹Urology, Tokyo Women's Medical University, Tokyo, Japan; ²Urology, Osaka Graduate School of Medicine, Suita, Osaka, Japan.
BackgroundKidney transplantation from living donors is an important treatment for patients with kidney failure. An accurate evaluation of renal function must be conducted before and…
2018 American Transplant Congress
The Efficacy of Laser Speckle Flowgraphy Device for Intraoperative Evaluation of Renal Blood Flow after Reperfusion
M. Muramatsu,¹ Y. Itabashi,¹ Y. Takahashi,² K. Sakurabayashi,¹ T. Mizutani,¹ Y. Hyodo,¹ Y. Hamasaki,² T. Kawamura,¹ K. Sakai,¹ S. Shishido.^1,2
¹Nephrology, Toho University Faculty of Medicine, Tokyo, Japan; ²Pediatric Nephrology, Toho University Faculty of Medicine, Tokyo, Japan.
Purpose:Laser speckle flowgraphy (LSFG) is a device to monitor cutaneous and ocular fundus blood flow. However, there is no report that the device was used…